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NBIX vs. GMED
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

NBIX vs. GMED - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Neurocrine Biosciences, Inc. (NBIX) and Globus Medical, Inc. (GMED). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, NBIX achieves a 24.87% return, which is significantly higher than GMED's -10.54% return. Over the past 10 years, NBIX has outperformed GMED with an annualized return of 13.85%, while GMED has yielded a comparatively lower 12.07% annualized return.


NBIX

1D
-1.91%
1M
8.85%
6M
30.43%
YTD
24.87%
1Y
32.71%
3Y*
21.73%
5Y*
12.33%
10Y*
13.85%

GMED

1D
1.92%
1M
-2.99%
6M
-17.32%
YTD
-10.54%
1Y
36.75%
3Y*
8.91%
5Y*
-0.63%
10Y*
12.07%
*Multi-year figures are annualized to reflect compound growth (CAGR)

NBIX vs. GMED - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
NBIX
Neurocrine Biosciences, Inc.
24.87%3.90%3.60%10.31%40.24%-11.14%-10.83%50.53%-7.96%100.49%
GMED
Globus Medical, Inc.
-10.54%5.56%55.21%-28.25%2.87%10.70%10.77%36.04%5.30%65.66%

Correlation

The correlation between NBIX and GMED is 0.19, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.19

Correlation (3Y)
Calculated over the trailing 3-year period

0.22

Correlation (5Y)
Calculated over the trailing 5-year period

0.28

Correlation (10Y)
Calculated over the trailing 10-year period

0.29

Correlation (All Time)
Calculated using the full available price history since Aug 3, 2012

0.29

The correlation between NBIX and GMED shifts across timeframes, from 0.19 (1 year) to 0.29 (10 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

NBIX:

$17.81B

GMED:

$10.53B

EPS

NBIX:

$6.50

GMED:

$4.28

PE Ratio

NBIX:

27.23

GMED:

18.23

PEG Ratio

NBIX:

0.54

GMED:

0.19

PS Ratio

NBIX:

5.87

GMED:

3.45

PB Ratio

NBIX:

5.37

GMED:

2.28

Total Revenue (TTM)

NBIX:

$3.10B

GMED:

$3.10B

Gross Profit (TTM)

NBIX:

$3.05B

GMED:

$1.58B

EBITDA (TTM)

NBIX:

$881.20M

GMED:

$803.34M

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Return for Risk

NBIX vs. GMED — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

NBIX
NBIX Risk / Return Rank: 7373
Overall Rank
NBIX Sharpe Ratio Rank: 7676
Sharpe Ratio Rank
NBIX Sortino Ratio Rank: 7171
Sortino Ratio Rank
NBIX Omega Ratio Rank: 7171
Omega Ratio Rank
NBIX Calmar Ratio Rank: 7373
Calmar Ratio Rank
NBIX Martin Ratio Rank: 7272
Martin Ratio Rank

GMED
GMED Risk / Return Rank: 7373
Overall Rank
GMED Sharpe Ratio Rank: 6969
Sharpe Ratio Rank
GMED Sortino Ratio Rank: 7575
Sortino Ratio Rank
GMED Omega Ratio Rank: 7272
Omega Ratio Rank
GMED Calmar Ratio Rank: 7575
Calmar Ratio Rank
GMED Martin Ratio Rank: 7575
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

NBIX vs. GMED - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Neurocrine Biosciences, Inc. (NBIX) and Globus Medical, Inc. (GMED). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


NBIXGMEDDifference
Sharpe ratioReturn per unit of total volatility

+0.28

Sortino ratioReturn per unit of downside risk

-0.26

Omega ratioGain probability vs. loss probability

1.20

1.21

0.00

Calmar ratioReturn relative to maximum drawdown

1.50

1.60

-0.09

Martin ratioReturn relative to average drawdown

3.29

3.87

-0.57

NBIX vs. GMED - Sharpe Ratio Comparison

The current NBIX Sharpe Ratio is 0.99, which is higher than the GMED Sharpe Ratio of 0.71. The chart below compares the historical Sharpe Ratios of NBIX and GMED, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

NBIX vs. GMED - Drawdown Comparison

The maximum NBIX drawdown since its inception was -97.21%, which is greater than GMED's maximum drawdown of -47.91%. Use the drawdown chart below to compare losses from any high point for NBIX and GMED.


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Drawdown Indicators


NBIXGMEDDifference

Max Drawdown

Largest peak-to-trough decline

-97.21%

-47.91%

-49.30%

Max Drawdown (1Y)

Largest decline over 1 year

-20.90%

-22.10%

+1.20%

Max Drawdown (3Y)

Largest decline over 3 years

-42.89%

-44.40%

+1.51%

Max Drawdown (5Y)

Largest decline over 5 years

-42.89%

-47.91%

+5.02%

Max Drawdown (10Y)

Largest decline over 10 years

-46.39%

-47.91%

+1.52%

Current Drawdown

Current decline from peak

-1.91%

-19.32%

+17.41%

Average Drawdown

Average peak-to-trough decline

-43.74%

-15.33%

-28.41%

Ulcer Index

Depth and duration of drawdowns from previous peaks

9.52%

9.13%

+0.39%

Volatility

NBIX vs. GMED - Volatility Comparison

The current volatility for Neurocrine Biosciences, Inc. (NBIX) is 8.08%, while Globus Medical, Inc. (GMED) has a volatility of 13.69%. This indicates that NBIX experiences smaller price fluctuations and is considered to be less risky than GMED based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


NBIXGMEDDifference

Volatility (1M)

Calculated over the trailing 1-month period

8.08%

13.69%

-5.61%

Volatility (6M)

Calculated over the trailing 6-month period

23.42%

25.33%

-1.91%

Volatility (1Y)

Calculated over the trailing 1-year period

31.73%

49.46%

-17.73%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

32.83%

38.27%

-5.44%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

39.03%

35.68%

+3.35%

Dividends

NBIX vs. GMED - Dividend Comparison

Neither NBIX nor GMED has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

NBIX vs. GMED - Financials Comparison

This section allows you to compare key financial metrics between Neurocrine Biosciences, Inc. and Globus Medical, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


200.00M300.00M400.00M500.00M600.00M700.00M800.00MJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025AprilJulyOctober2026
814.50M
759.85M
(NBIX) Total Revenue
(GMED) Total Revenue
Values in USD except per share items

NBIX vs. GMED - Profitability Comparison

The chart below illustrates the profitability comparison between Neurocrine Biosciences, Inc. and Globus Medical, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

0.0%20.0%40.0%60.0%80.0%100.0%JulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025AprilJulyOctober2026
98.3%
0
Portfolio components
NBIX - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported a gross profit of 800.70M and revenue of 814.50M. Therefore, the gross margin over that period was 98.3%.

GMED - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jul 2026, Globus Medical, Inc. reported a gross profit of 0.00 and revenue of 759.85M. Therefore, the gross margin over that period was 0.0%.

NBIX - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported an operating income of 193.40M and revenue of 814.50M, resulting in an operating margin of 23.7%.

GMED - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jul 2026, Globus Medical, Inc. reported an operating income of 150.39M and revenue of 759.85M, resulting in an operating margin of 19.8%.

NBIX - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported a net income of 197.90M and revenue of 814.50M, resulting in a net margin of 24.3%.

GMED - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jul 2026, Globus Medical, Inc. reported a net income of 124.30M and revenue of 759.85M, resulting in a net margin of 16.4%.


Frequently Asked Questions


NBIX and GMED have a correlation of 0.19, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

GMED has higher volatility (13.69%) compared to NBIX (8.08%). In terms of maximum drawdown, NBIX dropped -97.21% vs GMED's -47.91%.

NBIX currently has the higher Sharpe Ratio (0.99 vs 0.71), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

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