NBIX vs. UTHR
NBIX (Neurocrine Biosciences, Inc.) and UTHR (United Therapeutics Corporation) are both stocks. Both are in the Healthcare sector — NBIX in Drug Manufacturers - Specialty & Generic, UTHR in Biotechnology. Over the past 10 years, NBIX returned 12.80%/yr vs 16.80%/yr for UTHR. At a 0.34 correlation, their price movements are largely independent.
Performance
NBIX vs. UTHR - Performance Comparison
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Returns By Period
In the year-to-date period, NBIX achieves a 16.41% return, which is significantly higher than UTHR's 12.77% return. Over the past 10 years, NBIX has underperformed UTHR with an annualized return of 12.80%, while UTHR has yielded a comparatively higher 16.80% annualized return.
NBIX
- 1D
- 6.63%
- 1M
- 23.15%
- YTD
- 16.41%
- 6M
- 8.65%
- 1Y
- 32.09%
- 3Y*
- 21.38%
- 5Y*
- 11.83%
- 10Y*
- 12.80%
UTHR
- 1D
- 1.74%
- 1M
- -5.46%
- YTD
- 12.77%
- 6M
- 14.24%
- 1Y
- 69.48%
- 3Y*
- 36.25%
- 5Y*
- 25.58%
- 10Y*
- 16.80%
NBIX vs. UTHR - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
NBIX Neurocrine Biosciences, Inc. | 16.41% | 3.90% | 3.60% | 10.31% | 40.24% | -11.14% | -10.83% | 50.53% | -7.96% | 100.49% |
UTHR United Therapeutics Corporation | 12.77% | 38.09% | 60.46% | -20.93% | 28.70% | 42.35% | 72.33% | -19.12% | -26.39% | 3.15% |
Correlation
The correlation between NBIX and UTHR is 0.32, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.32 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.32 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.30 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.33 |
Correlation (All Time) Calculated using the full available price history since Jun 18, 1999 | 0.34 |
Fundamentals
NBIX:
$17.07B
UTHR:
$25.93B
NBIX:
$6.53
UTHR:
$27.00
NBIX:
25.28
UTHR:
20.35
NBIX:
0.50
UTHR:
0.67
NBIX:
5.45
UTHR:
8.26
NBIX:
5.01
UTHR:
4.39
NBIX:
$3.10B
UTHR:
$3.17B
NBIX:
$3.05B
UTHR:
$2.74B
NBIX:
$881.20M
UTHR:
$1.75B
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Return for Risk
NBIX vs. UTHR — Risk / Return Rank
NBIX
UTHR
NBIX vs. UTHR - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Neurocrine Biosciences, Inc. (NBIX) and United Therapeutics Corporation (UTHR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| NBIX | UTHR | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.37 | ||
| Sortino ratioReturn per unit of downside risk | -1.28 | ||
| Omega ratioGain probability vs. loss probability | 1.21 | 1.38 | -0.17 |
| Calmar ratioReturn relative to maximum drawdown | 1.54 | 4.27 | -2.73 |
| Martin ratioReturn relative to average drawdown | 3.39 | 11.01 | -7.62 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| NBIX | UTHR | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.04 | 1.40 | -0.37 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.36 | 0.73 | -0.37 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.33 | 0.48 | -0.15 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.15 | 0.38 | -0.24 |
Drawdowns
NBIX vs. UTHR - Drawdown Comparison
The maximum NBIX drawdown since its inception was -97.21%, roughly equal to the maximum UTHR drawdown of -93.18%. Use the drawdown chart below to compare losses from any high point for NBIX and UTHR.
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Drawdown Indicators
| NBIX | UTHR | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -97.21% | -93.18% | -4.03% |
Max Drawdown (1Y)Largest decline over 1 year | -20.90% | -16.35% | -4.55% |
Max Drawdown (3Y)Largest decline over 3 years | -42.89% | -33.00% | -9.89% |
Max Drawdown (5Y)Largest decline over 5 years | -42.89% | -33.00% | -9.89% |
Max Drawdown (10Y)Largest decline over 10 years | -46.39% | -55.56% | +9.17% |
Current DrawdownCurrent decline from peak | 0.00% | -7.92% | +7.92% |
Average DrawdownAverage peak-to-trough decline | -43.85% | -35.32% | -8.53% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 9.48% | 6.33% | +3.15% |
Volatility
NBIX vs. UTHR - Volatility Comparison
Neurocrine Biosciences, Inc. (NBIX) has a higher volatility of 12.60% compared to United Therapeutics Corporation (UTHR) at 8.33%. This indicates that NBIX's price experiences larger fluctuations and is considered to be riskier than UTHR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| NBIX | UTHR | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 12.60% | 8.33% | +4.27% |
Volatility (6M)Calculated over the trailing 6-month period | 23.57% | 26.06% | -2.49% |
Volatility (1Y)Calculated over the trailing 1-year period | 31.08% | 49.78% | -18.70% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 32.72% | 35.15% | -2.43% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 39.19% | 35.10% | +4.09% |
Dividends
NBIX vs. UTHR - Dividend Comparison
Neither NBIX nor UTHR has paid dividends to shareholders.
Financials
NBIX vs. UTHR - Financials Comparison
This section allows you to compare key financial metrics between Neurocrine Biosciences, Inc. and United Therapeutics Corporation. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
NBIX vs. UTHR - Profitability Comparison
NBIX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Neurocrine Biosciences, Inc. reported a gross profit of 800.70M and revenue of 814.50M. Therefore, the gross margin over that period was 98.3%.
UTHR - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, United Therapeutics Corporation reported a gross profit of 648.10M and revenue of 781.50M. Therefore, the gross margin over that period was 82.9%.
NBIX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Neurocrine Biosciences, Inc. reported an operating income of 193.40M and revenue of 814.50M, resulting in an operating margin of 23.7%.
UTHR - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, United Therapeutics Corporation reported an operating income of 325.80M and revenue of 781.50M, resulting in an operating margin of 41.7%.
NBIX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Neurocrine Biosciences, Inc. reported a net income of 197.90M and revenue of 814.50M, resulting in a net margin of 24.3%.
UTHR - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, United Therapeutics Corporation reported a net income of 274.90M and revenue of 781.50M, resulting in a net margin of 35.2%.
Frequently Asked Questions
NBIX and UTHR have a correlation of 0.32, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
NBIX has higher volatility (12.60%) compared to UTHR (8.33%). In terms of maximum drawdown, NBIX dropped -97.21% vs UTHR's -93.18%.
UTHR currently has the higher Sharpe Ratio (1.40 vs 1.04), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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