GMED vs. ISRG

Last updated Apr 2, 2026

Compare and contrast key facts about Globus Medical, Inc. (GMED) and Intuitive Surgical, Inc. (ISRG).

Performance

GMED vs. ISRG - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Globus Medical, Inc. (GMED) and Intuitive Surgical, Inc. (ISRG). The values are adjusted to include any dividend payments, if applicable.

GMED vs. ISRG - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
GMED Globus Medical, Inc.	0.49%	5.56%	55.21%	-28.25%	2.87%	10.70%	10.77%	36.04%	5.30%	65.66%
ISRG Intuitive Surgical, Inc.	-17.99%	8.51%	54.72%	27.14%	-26.15%	31.76%	38.39%	23.43%	31.23%	72.64%

Fundamentals

Market Cap GMED : $11.98B ISRG : $167.39B
EPS GMED : $3.95 ISRG : $7.89
PE Ratio GMED : 22.21 ISRG : 58.89
PEG Ratio GMED : 0.23 ISRG : 3.60
PS Ratio GMED : 4.06 ISRG : 16.71
PB Ratio GMED : 2.62 ISRG : 9.39
Total Revenue (TTM) GMED : $2.94B ISRG : $10.06B
Gross Profit (TTM) GMED : $1.39B ISRG : $6.64B
EBITDA (TTM) GMED : $742.04M ISRG : $3.62B

Returns By Period

In the year-to-date period, GMED achieves a 0.49% return, which is significantly higher than ISRG's -17.99% return. Over the past 10 years, GMED has underperformed ISRG with an annualized return of 13.94%, while ISRG has yielded a comparatively higher 21.29% annualized return.

GMED

• 1D: 1.83%
• 1M: -6.46%
• YTD: 0.49%
• 6M: 49.57%
• 1Y: 19.55%
• 3Y*: 15.71%
• 5Y*: 7.24%
• 10Y*: 13.94%

ISRG

• 1D: 0.75%
• 1M: -6.41%
• YTD: -17.99%
• 6M: 6.03%
• 1Y: -6.43%
• 3Y*: 22.05%
• 5Y*: 13.26%
• 10Y*: 21.29%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

GMED vs. ISRG — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

GMED

GMED Risk / Return Rank: 55
GMED Sharpe Ratio Rank: 54
GMED Sortino Ratio Rank: 54
GMED Omega Ratio Rank: 59
GMED Calmar Ratio Rank: 56
GMED Martin Ratio Rank: 54

ISRG

ISRG Risk / Return Rank: 31
ISRG Sharpe Ratio Rank: 32
ISRG Sortino Ratio Rank: 28
ISRG Omega Ratio Rank: 28
ISRG Calmar Ratio Rank: 33
ISRG Martin Ratio Rank: 33

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

GMED vs. ISRG - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Globus Medical, Inc. (GMED) and Intuitive Surgical, Inc. (ISRG). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	GMED	ISRG	Difference
Sharpe ratio Return per unit of total volatility	0.37	-0.19	+0.56
Sortino ratio Return per unit of downside risk	1.01	-0.05	+1.06
Omega ratio Gain probability vs. loss probability	1.16	0.99	+0.16
Calmar ratio Return relative to maximum drawdown	0.64	-0.26	+0.89
Martin ratio Return relative to average drawdown	1.20	-0.48	+1.69
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

GMED vs. ISRG - Sharpe Ratio Comparison

The current GMED Sharpe Ratio is 0.37, which is higher than the ISRG Sharpe Ratio of -0.19. The chart below compares the historical Sharpe Ratios of GMED and ISRG, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	GMED	ISRG	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.37	-0.19	+0.56
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.19	0.40	-0.21
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.40	0.67	-0.27
Sharpe Ratio (All Time) Calculated using the full available price history	0.42	0.49	-0.07

Correlation

The correlation between GMED and ISRG is 0.43, which is considered to be moderate. This suggests that the two assets have some degree of positive relationship in their price movements. Moderate correlation can be acceptable for portfolio diversification, offering a balance between risk and potential returns.

Dividends

GMED vs. ISRG - Dividend Comparison

Neither GMED nor ISRG has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

GMED vs. ISRG - Drawdown Comparison

The maximum GMED drawdown since its inception was -47.91%, smaller than the maximum ISRG drawdown of -82.26%. Use the drawdown chart below to compare losses from any high point for GMED and ISRG.

Drawdown Indicators

	GMED	ISRG	Difference
Max Drawdown Largest peak-to-trough decline	-47.91%	-82.26%	+34.35%
Max Drawdown (1Y) Largest decline over 1 year	-31.27%	-24.09%	-7.18%
Max Drawdown (5Y) Largest decline over 5 years	-47.91%	-49.90%	+1.99%
Max Drawdown (10Y) Largest decline over 10 years	-47.91%	-49.90%	+1.99%
Current Drawdown Current decline from peak	-9.28%	-23.92%	+14.64%
Average Drawdown Average peak-to-trough decline	-15.38%	-21.24%	+5.86%
Ulcer Index Depth and duration of drawdowns from previous peaks	16.51%	12.86%	+3.65%

Volatility

GMED vs. ISRG - Volatility Comparison

Globus Medical, Inc. (GMED) has a higher volatility of 8.07% compared to Intuitive Surgical, Inc. (ISRG) at 6.54%. This indicates that GMED's price experiences larger fluctuations and is considered to be riskier than ISRG based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	GMED	ISRG	Difference
Volatility (1M) Calculated over the trailing 1-month period	8.07%	6.54%	+1.53%
Volatility (6M) Calculated over the trailing 6-month period	36.51%	22.05%	+14.46%
Volatility (1Y) Calculated over the trailing 1-year period	53.49%	33.82%	+19.67%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	37.45%	33.01%	+4.44%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	35.32%	32.09%	+3.23%

Financials

GMED vs. ISRG - Profitability Comparison

The chart below illustrates the profitability comparison between Globus Medical, Inc. and Intuitive Surgical, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

GMED - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Globus Medical, Inc. reported a gross profit of 0.00 and revenue of 826.42M. Therefore, the gross margin over that period was 0.0%.

ISRG - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Intuitive Surgical, Inc. reported a gross profit of 1.90B and revenue of 2.87B. Therefore, the gross margin over that period was 66.4%.

GMED - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Globus Medical, Inc. reported an operating income of 171.70M and revenue of 826.42M, resulting in an operating margin of 20.8%.

ISRG - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Intuitive Surgical, Inc. reported an operating income of 864.30M and revenue of 2.87B, resulting in an operating margin of 30.2%.

GMED - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Globus Medical, Inc. reported a net income of 140.59M and revenue of 826.42M, resulting in a net margin of 17.0%.

ISRG - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Intuitive Surgical, Inc. reported a net income of 794.80M and revenue of 2.87B, resulting in a net margin of 27.7%.