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Neurocrine Biosciences, Inc. (NBIX)
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN
US64125C1099
CUSIP
64125C109
IPO Date
May 23, 1996

Highlights

Market Cap
$13.50B
Enterprise Value
$13.21B
EPS (TTM)
$4.69
PE Ratio
28.08
PEG Ratio
0.55
Total Revenue (TTM)
$2.86B
Gross Profit (TTM)
$2.81B
EBITDA (TTM)
$719.10M
Year Range
$84.23 - $160.18
Target Price
$169.17
ROA (TTM)
10.33%
ROE (TTM)
14.71%

Share Price Chart


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Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in Neurocrine Biosciences, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


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S&P 500 Index

Returns By Period

Neurocrine Biosciences, Inc. (NBIX) has returned -7.11% so far this year and 19.11% over the past 12 months. Over the last decade, NBIX has posted an annualized return of 12.23%, slightly higher than the S&P 500 Index benchmark’s 12.16%.


Neurocrine Biosciences, Inc.

1D
2.35%
1M
-0.39%
YTD
-7.11%
6M
-6.15%
1Y
19.11%
3Y*
9.18%
5Y*
6.06%
10Y*
12.23%

Benchmark (S&P 500 Index)

1D
2.91%
1M
-5.09%
YTD
-4.63%
6M
-2.39%
1Y
16.33%
3Y*
16.69%
5Y*
10.18%
10Y*
12.16%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since May 23, 1996, NBIX's average daily return is +0.11%, while the average monthly return is +2.07%. At this rate, your investment would double in approximately 2.8 years.

Historically, 51% of months were positive and 49% were negative. The best month was Nov 1999 with a return of +91.0%, while the worst month was May 2006 at -65.6%. The longest winning streak lasted 8 consecutive months, and the longest losing streak was 6 months.

On a daily basis, NBIX closed higher 49% of trading days. The best single day was Jan 7, 2014 with a return of +89.7%, while the worst single day was May 16, 2006 at -62.0%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-4.07%-2.80%-0.39%-7.11%
202511.22%-21.80%-6.84%-2.63%14.24%2.17%2.02%8.87%0.56%2.02%6.25%-6.79%3.90%
20246.08%-6.70%5.77%-0.28%-1.55%1.67%2.83%-10.25%-9.32%4.38%5.39%7.69%3.60%
2023-7.12%-7.06%-1.82%-0.18%-11.39%5.33%8.05%6.87%3.32%-1.39%5.09%13.01%10.31%
2022-7.22%13.73%4.32%-3.97%3.84%4.27%-3.44%11.15%1.51%8.39%10.37%-6.00%40.24%
202114.50%-0.22%-11.20%-2.84%1.83%1.14%-4.22%2.13%0.75%9.91%-21.02%2.31%-11.14%

Benchmark Metrics

Neurocrine Biosciences, Inc. has an annualized alpha of 17.52%, beta of 1.17, and R² of 0.13 versus S&P 500 Index. Calculated based on daily prices since May 24, 1996.

  • This stock captured 110.81% of S&P 500 Index gains and 108.38% of its losses — amplifying both gains and losses, but participating more in upside than downside.
  • R² of 0.13 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
17.52%
Beta
1.17
0.13
Upside Capture
110.81%
Downside Capture
108.38%

Return for Risk

Risk / Return Rank

NBIX ranks 58 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.


NBIX Risk / Return Rank: 5858
Overall Rank
NBIX Sharpe Ratio Rank: 6161
Sharpe Ratio Rank
NBIX Sortino Ratio Rank: 5454
Sortino Ratio Rank
NBIX Omega Ratio Rank: 5555
Omega Ratio Rank
NBIX Calmar Ratio Rank: 5858
Calmar Ratio Rank
NBIX Martin Ratio Rank: 6060
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Neurocrine Biosciences, Inc. (NBIX) and compare them to a chosen benchmark (S&P 500 Index).


NBIXBenchmarkDifference

Sharpe ratio

Return per unit of total volatility

0.57

0.90

-0.33

Sortino ratio

Return per unit of downside risk

0.96

1.39

-0.42

Omega ratio

Gain probability vs. loss probability

1.14

1.21

-0.07

Calmar ratio

Return relative to maximum drawdown

0.79

1.40

-0.61

Martin ratio

Return relative to average drawdown

1.89

6.61

-4.72

Explore NBIX risk-adjusted metrics in detail

Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.

Dividends

Dividend History


Neurocrine Biosciences, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Neurocrine Biosciences, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Neurocrine Biosciences, Inc. was 97.21%, occurring on Nov 12, 2009. Recovery took 2007 trading sessions.

The current Neurocrine Biosciences, Inc. drawdown is 15.35%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-97.21%Mar 16, 2006924Nov 12, 20092007Nov 2, 20172931
-70.28%Feb 27, 1997605Jul 22, 199986Nov 22, 1999691
-66.15%Mar 6, 2000257Mar 12, 2001173Nov 20, 2001430
-54.12%Dec 26, 2001135Jul 10, 2002228Jun 5, 2003363
-50.71%Apr 28, 2004255May 2, 2005207Feb 27, 2006462

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Neurocrine Biosciences, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Neurocrine Biosciences, Inc. is priced in the market compared to other companies in the Drug Manufacturers - Specialty & Generic industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PE Ratio

The chart displays the Price-to-Earnings (P/E) ratio for NBIX, comparing it with other companies in the Drug Manufacturers - Specialty & Generic industry. Currently, NBIX has a P/E ratio of 28.1. This P/E ratio is significantly higher than those of industry peers. This could indicate that the stock is overvalued or that investors expect strong future growth.

PEG Ratio

The chart shows the Price/Earnings to Growth (PEG) ratio for NBIX compared to other companies in the Drug Manufacturers - Specialty & Generic industry. NBIX currently has a PEG ratio of 0.6. This PEG ratio is higher than the industry average, which may suggest the stock is overvalued relative to its expected earnings growth.

PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for NBIX relative to other companies in the Drug Manufacturers - Specialty & Generic industry. Currently, NBIX has a P/S ratio of 4.7. This P/S ratio is high relative to other companies in the industry. It could mean the stock is overvalued, or that investors expect strong future growth and profitability.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for NBIX in comparison with other companies in the Drug Manufacturers - Specialty & Generic industry. Currently, NBIX has a P/B value of 4.2. This P/B ratio is higher than most companies in the industry. It may suggest the stock is overvalued or that investors expect the company to generate high returns on its assets.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items