PortfoliosLab logoPortfoliosLab logo
GMED vs. NBIX
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

GMED vs. NBIX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Globus Medical, Inc. (GMED) and Neurocrine Biosciences, Inc. (NBIX). The values are adjusted to include any dividend payments, if applicable.

Loading charts...

Returns By Period

In the year-to-date period, GMED achieves a -10.54% return, which is significantly lower than NBIX's 24.87% return. Over the past 10 years, GMED has underperformed NBIX with an annualized return of 12.07%, while NBIX has yielded a comparatively higher 13.85% annualized return.


GMED

1D
1.92%
1M
-2.99%
6M
-17.32%
YTD
-10.54%
1Y
36.75%
3Y*
8.91%
5Y*
-0.63%
10Y*
12.07%

NBIX

1D
-1.91%
1M
8.85%
6M
30.43%
YTD
24.87%
1Y
32.71%
3Y*
21.73%
5Y*
12.33%
10Y*
13.85%
*Multi-year figures are annualized to reflect compound growth (CAGR)

GMED vs. NBIX - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
GMED
Globus Medical, Inc.
-10.54%5.56%55.21%-28.25%2.87%10.70%10.77%36.04%5.30%65.66%
NBIX
Neurocrine Biosciences, Inc.
24.87%3.90%3.60%10.31%40.24%-11.14%-10.83%50.53%-7.96%100.49%

Correlation

The correlation between GMED and NBIX is 0.19, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.19

Correlation (3Y)
Calculated over the trailing 3-year period

0.22

Correlation (5Y)
Calculated over the trailing 5-year period

0.28

Correlation (10Y)
Calculated over the trailing 10-year period

0.29

Correlation (All Time)
Calculated using the full available price history since Aug 3, 2012

0.29

The correlation between GMED and NBIX shifts across timeframes, from 0.19 (1 year) to 0.29 (10 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

GMED:

$10.53B

NBIX:

$17.81B

EPS

GMED:

$4.28

NBIX:

$6.50

PE Ratio

GMED:

18.23

NBIX:

27.23

PEG Ratio

GMED:

0.19

NBIX:

0.54

PS Ratio

GMED:

3.45

NBIX:

5.87

PB Ratio

GMED:

2.28

NBIX:

5.37

Total Revenue (TTM)

GMED:

$3.10B

NBIX:

$3.10B

Gross Profit (TTM)

GMED:

$1.58B

NBIX:

$3.05B

EBITDA (TTM)

GMED:

$803.34M

NBIX:

$881.20M

Compare stocks, funds, or ETFs

Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.


Return for Risk

GMED vs. NBIX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

GMED
GMED Risk / Return Rank: 7373
Overall Rank
GMED Sharpe Ratio Rank: 6969
Sharpe Ratio Rank
GMED Sortino Ratio Rank: 7575
Sortino Ratio Rank
GMED Omega Ratio Rank: 7272
Omega Ratio Rank
GMED Calmar Ratio Rank: 7575
Calmar Ratio Rank
GMED Martin Ratio Rank: 7575
Martin Ratio Rank

NBIX
NBIX Risk / Return Rank: 7373
Overall Rank
NBIX Sharpe Ratio Rank: 7676
Sharpe Ratio Rank
NBIX Sortino Ratio Rank: 7171
Sortino Ratio Rank
NBIX Omega Ratio Rank: 7171
Omega Ratio Rank
NBIX Calmar Ratio Rank: 7373
Calmar Ratio Rank
NBIX Martin Ratio Rank: 7272
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

GMED vs. NBIX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Globus Medical, Inc. (GMED) and Neurocrine Biosciences, Inc. (NBIX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


GMEDNBIXDifference
Sharpe ratioReturn per unit of total volatility

-0.28

Sortino ratioReturn per unit of downside risk

+0.26

Omega ratioGain probability vs. loss probability

1.21

1.20

0.00

Calmar ratioReturn relative to maximum drawdown

1.60

1.50

+0.09

Martin ratioReturn relative to average drawdown

3.87

3.29

+0.57

GMED vs. NBIX - Sharpe Ratio Comparison

The current GMED Sharpe Ratio is 0.71, which is comparable to the NBIX Sharpe Ratio of 0.99. The chart below compares the historical Sharpe Ratios of GMED and NBIX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


Loading charts...

Drawdowns

GMED vs. NBIX - Drawdown Comparison

The maximum GMED drawdown since its inception was -47.91%, smaller than the maximum NBIX drawdown of -97.21%. Use the drawdown chart below to compare losses from any high point for GMED and NBIX.


Loading charts...

Drawdown Indicators


GMEDNBIXDifference

Max Drawdown

Largest peak-to-trough decline

-47.91%

-97.21%

+49.30%

Max Drawdown (1Y)

Largest decline over 1 year

-22.10%

-20.90%

-1.20%

Max Drawdown (3Y)

Largest decline over 3 years

-44.40%

-42.89%

-1.51%

Max Drawdown (5Y)

Largest decline over 5 years

-47.91%

-42.89%

-5.02%

Max Drawdown (10Y)

Largest decline over 10 years

-47.91%

-46.39%

-1.52%

Current Drawdown

Current decline from peak

-19.32%

-1.91%

-17.41%

Average Drawdown

Average peak-to-trough decline

-15.33%

-43.74%

+28.41%

Ulcer Index

Depth and duration of drawdowns from previous peaks

9.13%

9.52%

-0.39%

Volatility

GMED vs. NBIX - Volatility Comparison

Globus Medical, Inc. (GMED) has a higher volatility of 13.69% compared to Neurocrine Biosciences, Inc. (NBIX) at 8.08%. This indicates that GMED's price experiences larger fluctuations and is considered to be riskier than NBIX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


Loading charts...

Volatility by Period


GMEDNBIXDifference

Volatility (1M)

Calculated over the trailing 1-month period

13.69%

8.08%

+5.61%

Volatility (6M)

Calculated over the trailing 6-month period

25.33%

23.42%

+1.91%

Volatility (1Y)

Calculated over the trailing 1-year period

49.46%

31.73%

+17.73%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

38.27%

32.83%

+5.44%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

35.68%

39.03%

-3.35%

Dividends

GMED vs. NBIX - Dividend Comparison

Neither GMED nor NBIX has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

GMED vs. NBIX - Financials Comparison

This section allows you to compare key financial metrics between Globus Medical, Inc. and Neurocrine Biosciences, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


200.00M300.00M400.00M500.00M600.00M700.00M800.00MJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025AprilJulyOctober2026
759.85M
814.50M
(GMED) Total Revenue
(NBIX) Total Revenue
Values in USD except per share items

GMED vs. NBIX - Profitability Comparison

The chart below illustrates the profitability comparison between Globus Medical, Inc. and Neurocrine Biosciences, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

0.0%20.0%40.0%60.0%80.0%100.0%JulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025AprilJulyOctober20260
98.3%
Portfolio components
GMED - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jul 2026, Globus Medical, Inc. reported a gross profit of 0.00 and revenue of 759.85M. Therefore, the gross margin over that period was 0.0%.

NBIX - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported a gross profit of 800.70M and revenue of 814.50M. Therefore, the gross margin over that period was 98.3%.

GMED - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jul 2026, Globus Medical, Inc. reported an operating income of 150.39M and revenue of 759.85M, resulting in an operating margin of 19.8%.

NBIX - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported an operating income of 193.40M and revenue of 814.50M, resulting in an operating margin of 23.7%.

GMED - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jul 2026, Globus Medical, Inc. reported a net income of 124.30M and revenue of 759.85M, resulting in a net margin of 16.4%.

NBIX - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported a net income of 197.90M and revenue of 814.50M, resulting in a net margin of 24.3%.


Frequently Asked Questions


GMED and NBIX have a correlation of 0.19, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

GMED has higher volatility (13.69%) compared to NBIX (8.08%). In terms of maximum drawdown, GMED dropped -47.91% vs NBIX's -97.21%.

NBIX currently has the higher Sharpe Ratio (0.99 vs 0.71), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for GMED and NBIX

Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.

Open Portfolio Optimizer