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DTIL vs. ARWR
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

DTIL vs. ARWR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Precision BioSciences, Inc. (DTIL) and Arrowhead Pharmaceuticals, Inc. (ARWR). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, DTIL achieves a 45.19% return, which is significantly higher than ARWR's 9.28% return.


DTIL

1D
-4.43%
1M
-20.84%
YTD
45.19%
6M
19.37%
1Y
17.28%
3Y*
-35.49%
5Y*
-55.07%
10Y*

ARWR

1D
2.44%
1M
-5.03%
YTD
9.28%
6M
11.49%
1Y
336.79%
3Y*
26.25%
5Y*
-0.96%
10Y*
28.05%
*Multi-year figures are annualized to reflect compound growth (CAGR)

DTIL vs. ARWR - Yearly Performance Comparison


2026 (YTD)2025202420232022202120202019
DTIL
Precision BioSciences, Inc.
45.19%9.19%-65.21%-69.33%-83.92%-11.27%-39.96%-20.36%
ARWR
Arrowhead Pharmaceuticals, Inc.
9.28%253.14%-38.56%-24.56%-38.82%-13.59%20.97%250.64%

Correlation

The correlation between DTIL and ARWR is 0.25, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.25

Correlation (3Y)
Calculated over the trailing 3-year period

0.22

Correlation (5Y)
Calculated over the trailing 5-year period

0.35

Correlation (All Time)
Calculated using the full available price history since Mar 29, 2019

0.36

The correlation between DTIL and ARWR shifts across timeframes, from 0.22 (3 years) to 0.36 (all time), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

DTIL:

$148.79M

ARWR:

$10.33B

EPS

DTIL:

-$2.95

ARWR:

-$2.16

PS Ratio

DTIL:

2.02

ARWR:

16.27

PB Ratio

DTIL:

1.96

ARWR:

17.25

Total Revenue (TTM)

DTIL:

$45.07M

ARWR:

$622.01M

Gross Profit (TTM)

DTIL:

$32.19M

ARWR:

$529.27M

EBITDA (TTM)

DTIL:

-$30.02M

ARWR:

-$168.38M

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Return for Risk

DTIL vs. ARWR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

DTIL
DTIL Risk / Return Rank: 4949
Overall Rank
DTIL Sharpe Ratio Rank: 5050
Sharpe Ratio Rank
DTIL Sortino Ratio Rank: 5151
Sortino Ratio Rank
DTIL Omega Ratio Rank: 4848
Omega Ratio Rank
DTIL Calmar Ratio Rank: 4848
Calmar Ratio Rank
DTIL Martin Ratio Rank: 4747
Martin Ratio Rank

ARWR
ARWR Risk / Return Rank: 9898
Overall Rank
ARWR Sharpe Ratio Rank: 9999
Sharpe Ratio Rank
ARWR Sortino Ratio Rank: 9797
Sortino Ratio Rank
ARWR Omega Ratio Rank: 9595
Omega Ratio Rank
ARWR Calmar Ratio Rank: 9898
Calmar Ratio Rank
ARWR Martin Ratio Rank: 9898
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

DTIL vs. ARWR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Precision BioSciences, Inc. (DTIL) and Arrowhead Pharmaceuticals, Inc. (ARWR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


DTILARWRDifference
Sharpe ratioReturn per unit of total volatility

-4.97

Sortino ratioReturn per unit of downside risk

-3.84

Omega ratioGain probability vs. loss probability

1.10

1.59

-0.49

Calmar ratioReturn relative to maximum drawdown

0.30

13.77

-13.47

Martin ratioReturn relative to average drawdown

0.56

37.74

-37.18

DTIL vs. ARWR - Sharpe Ratio Comparison

The current DTIL Sharpe Ratio is 0.25, which is lower than the ARWR Sharpe Ratio of 5.22. The chart below compares the historical Sharpe Ratios of DTIL and ARWR, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Sharpe Ratios by Period


DTILARWRDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

0.25

5.22

-4.97

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

-0.70

-0.01

-0.68

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

0.38

Sharpe Ratio (All Time)

Calculated using the full available price history

-0.55

-0.01

-0.54

Drawdowns

DTIL vs. ARWR - Drawdown Comparison

The maximum DTIL drawdown since its inception was -99.39%, roughly equal to the maximum ARWR drawdown of -99.24%. Use the drawdown chart below to compare losses from any high point for DTIL and ARWR.


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Drawdown Indicators


DTILARWRDifference

Max Drawdown

Largest peak-to-trough decline

-99.39%

-99.24%

-0.15%

Max Drawdown (1Y)

Largest decline over 1 year

-58.54%

-24.64%

-33.90%

Max Drawdown (3Y)

Largest decline over 3 years

-85.40%

-74.70%

-10.70%

Max Drawdown (5Y)

Largest decline over 5 years

-99.16%

-88.94%

-10.22%

Max Drawdown (10Y)

Largest decline over 10 years

-88.96%

Current Drawdown

Current decline from peak

-98.98%

-55.35%

-43.63%

Average Drawdown

Average peak-to-trough decline

-77.65%

-81.24%

+3.59%

Ulcer Index

Depth and duration of drawdowns from previous peaks

30.78%

8.97%

+21.81%

Volatility

DTIL vs. ARWR - Volatility Comparison

Precision BioSciences, Inc. (DTIL) has a higher volatility of 20.95% compared to Arrowhead Pharmaceuticals, Inc. (ARWR) at 17.17%. This indicates that DTIL's price experiences larger fluctuations and is considered to be riskier than ARWR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


DTILARWRDifference

Volatility (1M)

Calculated over the trailing 1-month period

20.95%

17.17%

+3.78%

Volatility (6M)

Calculated over the trailing 6-month period

49.88%

39.41%

+10.47%

Volatility (1Y)

Calculated over the trailing 1-year period

68.81%

65.03%

+3.78%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

79.38%

65.03%

+14.35%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

84.87%

74.14%

+10.73%

Dividends

DTIL vs. ARWR - Dividend Comparison

Neither DTIL nor ARWR has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

DTIL vs. ARWR - Financials Comparison

This section allows you to compare key financial metrics between Precision BioSciences, Inc. and Arrowhead Pharmaceuticals, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.00100.00M200.00M300.00M400.00M500.00M20222023202420252026
10.84M
73.74M
(DTIL) Total Revenue
(ARWR) Total Revenue
Values in USD except per share items

Frequently Asked Questions


DTIL and ARWR have a correlation of 0.25, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

DTIL has higher volatility (20.95%) compared to ARWR (17.17%). In terms of maximum drawdown, DTIL dropped -99.39% vs ARWR's -99.24%.

ARWR currently has the higher Sharpe Ratio (5.22 vs 0.25), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

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