DTIL vs. ISRG
DTIL (Precision BioSciences, Inc.) and ISRG (Intuitive Surgical, Inc.) are both stocks. Both are in the Healthcare sector — DTIL in Biotechnology, ISRG in Medical Instruments & Supplies. Over the past 5 years, DTIL returned -55.07%/yr vs 8.00%/yr for ISRG. At a 0.23 correlation, their price movements are largely independent.
Performance
DTIL vs. ISRG - Performance Comparison
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Returns By Period
In the year-to-date period, DTIL achieves a 45.19% return, which is significantly higher than ISRG's -28.09% return.
DTIL
- 1D
- -4.43%
- 1M
- -20.84%
- YTD
- 45.19%
- 6M
- 19.37%
- 1Y
- 17.28%
- 3Y*
- -35.49%
- 5Y*
- -55.07%
- 10Y*
- —
ISRG
- 1D
- 1.24%
- 1M
- -9.96%
- YTD
- -28.09%
- 6M
- -28.51%
- 1Y
- -26.20%
- 3Y*
- 9.27%
- 5Y*
- 8.00%
- 10Y*
- 19.13%
DTIL vs. ISRG - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|---|
DTIL Precision BioSciences, Inc. | 45.19% | 9.19% | -65.21% | -69.33% | -83.92% | -11.27% | -39.96% | -20.36% |
ISRG Intuitive Surgical, Inc. | -28.09% | 8.51% | 54.72% | 27.14% | -26.15% | 31.76% | 38.39% | 5.02% |
Correlation
The correlation between DTIL and ISRG is 0.07, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.07 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.09 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.22 |
Correlation (All Time) Calculated using the full available price history since Mar 29, 2019 | 0.23 |
The correlation between DTIL and ISRG shifts across timeframes, from 0.07 (1 year) to 0.23 (all time), reflecting how their relationship changes across market environments.
Fundamentals
DTIL:
$148.79M
ISRG:
$146.54B
DTIL:
-$2.95
ISRG:
$8.24
DTIL:
2.02
ISRG:
13.91
DTIL:
1.96
ISRG:
8.33
DTIL:
$45.07M
ISRG:
$10.58B
DTIL:
$32.19M
ISRG:
$7.02B
DTIL:
-$30.02M
ISRG:
$3.76B
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Return for Risk
DTIL vs. ISRG — Risk / Return Rank
DTIL
ISRG
DTIL vs. ISRG - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Precision BioSciences, Inc. (DTIL) and Intuitive Surgical, Inc. (ISRG). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| DTIL | ISRG | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.11 | ||
| Sortino ratioReturn per unit of downside risk | +2.09 | ||
| Omega ratioGain probability vs. loss probability | 1.10 | 0.86 | +0.24 |
| Calmar ratioReturn relative to maximum drawdown | 0.30 | -0.82 | +1.11 |
| Martin ratioReturn relative to average drawdown | 0.56 | -1.65 | +2.21 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| DTIL | ISRG | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.25 | -0.85 | +1.11 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.70 | 0.24 | -0.94 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.59 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.55 | 0.47 | -1.02 |
Drawdowns
DTIL vs. ISRG - Drawdown Comparison
The maximum DTIL drawdown since its inception was -99.39%, which is greater than ISRG's maximum drawdown of -82.26%. Use the drawdown chart below to compare losses from any high point for DTIL and ISRG.
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Drawdown Indicators
| DTIL | ISRG | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.39% | -82.26% | -17.13% |
Max Drawdown (1Y)Largest decline over 1 year | -58.54% | -32.14% | -26.40% |
Max Drawdown (3Y)Largest decline over 3 years | -85.40% | -34.10% | -51.30% |
Max Drawdown (5Y)Largest decline over 5 years | -99.16% | -49.90% | -49.26% |
Max Drawdown (10Y)Largest decline over 10 years | — | -49.90% | — |
Current DrawdownCurrent decline from peak | -98.98% | -33.28% | -65.70% |
Average DrawdownAverage peak-to-trough decline | -77.65% | -21.27% | -56.38% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 30.78% | 15.91% | +14.87% |
Volatility
DTIL vs. ISRG - Volatility Comparison
Precision BioSciences, Inc. (DTIL) has a higher volatility of 20.95% compared to Intuitive Surgical, Inc. (ISRG) at 11.07%. This indicates that DTIL's price experiences larger fluctuations and is considered to be riskier than ISRG based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| DTIL | ISRG | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 20.95% | 11.07% | +9.88% |
Volatility (6M)Calculated over the trailing 6-month period | 49.88% | 20.23% | +29.65% |
Volatility (1Y)Calculated over the trailing 1-year period | 68.81% | 30.83% | +37.98% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 79.38% | 33.15% | +46.23% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 84.87% | 32.38% | +52.49% |
Dividends
DTIL vs. ISRG - Dividend Comparison
Neither DTIL nor ISRG has paid dividends to shareholders.
Financials
DTIL vs. ISRG - Financials Comparison
This section allows you to compare key financial metrics between Precision BioSciences, Inc. and Intuitive Surgical, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
DTIL and ISRG have a correlation of 0.07, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
DTIL has higher volatility (20.95%) compared to ISRG (11.07%). In terms of maximum drawdown, DTIL dropped -99.39% vs ISRG's -82.26%.
DTIL currently has the higher Sharpe Ratio (0.25 vs -0.85), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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