CNTA vs. KPTI
CNTA (Centessa Pharmaceuticals Limited) and KPTI (Karyopharm Therapeutics Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Their 0.19 correlation means their historical movements had little consistent relationship.
Performance
CNTA vs. KPTI - Performance Comparison
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Returns By Period
CNTA
- 1D
- —
- 1M
- —
- 6M
- —
- YTD
- —
- 1Y
- —
- 3Y*
- —
- 5Y*
- —
- 10Y*
- —
- ALL TIME*
- —
KPTI
- 1D
- -72.61%
- 1M
- -80.00%
- 6M
- -70.55%
- YTD
- -73.91%
- 1Y
- -51.15%
- 3Y*
- -58.57%
- 5Y*
- -56.62%
- 10Y*
- -32.96%
- ALL TIME*
- -32.15%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $12.61M | $7.85M | $5.63M |
CNTA vs. KPTI - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
CNTA Centessa Pharmaceuticals Limited | 61.94% | 49.31% | 110.43% | 156.77% | -72.47% | -44.40% |
KPTI Karyopharm Therapeutics Inc. | -73.91% | -27.45% | -21.82% | -74.56% | -47.12% | -31.08% |
Correlation
The correlation between CNTA and KPTI is 0.12, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.12 |
Correlation (3Y) Balances recent behavior with more history. | 0.20 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.19 |
Correlation (All Time) Calculated using the full available price history since May 28, 2021 | 0.19 |
Fundamentals
CNTA:
-$1.81
KPTI:
-$11.39
CNTA:
362.24
KPTI:
0.22
CNTA:
$15.00M
KPTI:
$151.12M
CNTA:
$15.00M
KPTI:
$145.13M
CNTA:
-$227.27M
KPTI:
-$93.05M
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Return for Risk
CNTA vs. KPTI — Risk / Return Rank
CNTA
Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.
KPTI
CNTA vs. KPTI - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Centessa Pharmaceuticals Limited (CNTA) and Karyopharm Therapeutics Inc. (KPTI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| CNTA | KPTI | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | — | — | |
| Sortino ratioReturn per unit of downside risk | — | — | |
| Omega ratioGain probability vs. loss probability | — | 1.05 | — |
| Calmar ratioReturn relative to maximum drawdown | — | -0.61 | — |
| Martin ratioReturn relative to average drawdown | — | -2.42 | — |
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Drawdowns
CNTA vs. KPTI - Drawdown Comparison
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Drawdown Indicators
| CNTA | KPTI | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | — | -99.73% | — |
Max Drawdown (1Y)Largest decline over 1 year | — | -82.01% | — |
Max Drawdown (3Y)Largest decline over 3 years | — | -92.93% | — |
Max Drawdown (5Y)Largest decline over 5 years | — | -99.11% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -99.54% | — |
Current DrawdownCurrent decline from peak | — | -99.73% | — |
Average DrawdownAverage peak-to-trough decline | — | -75.59% | — |
Ulcer IndexDepth and duration of drawdowns from previous peaks | — | 20.49% | — |
Volatility
CNTA vs. KPTI - Volatility Comparison
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Volatility by Period
| CNTA | KPTI | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | — | 131.26% | — |
Volatility (6M)Calculated over the trailing 6-month period | — | 144.90% | — |
Volatility (1Y)Calculated over the trailing 1-year period | — | 117.57% | — |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | — | 101.03% | — |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | — | 89.78% | — |
Dividends
CNTA vs. KPTI - Dividend Comparison
Neither CNTA nor KPTI has paid dividends to shareholders.
Financials
CNTA vs. KPTI - Financials Comparison
This section allows you to compare key financial metrics between Centessa Pharmaceuticals Limited and Karyopharm Therapeutics Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
CNTA and KPTI have a correlation of 0.12, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
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