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KPTI vs. CD
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

KPTI vs. CD - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Karyopharm Therapeutics Inc. (KPTI) and Chaince Digital Holdings Inc (CD). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, KPTI achieves a 22.28% return, which is significantly lower than CD's 60.97% return. Over the past 10 years, KPTI has underperformed CD with an annualized return of -23.93%, while CD has yielded a comparatively higher -21.69% annualized return.


KPTI

1D
-2.49%
1M
-3.23%
YTD
22.28%
6M
64.84%
1Y
111.76%
3Y*
-35.73%
5Y*
-41.77%
10Y*
-23.93%

CD

1D
-11.41%
1M
48.98%
YTD
60.97%
6M
13.64%
1Y
125.35%
3Y*
50.01%
5Y*
2.32%
10Y*
-21.69%
*Multi-year figures are annualized to reflect compound growth (CAGR)

KPTI vs. CD - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
KPTI
Karyopharm Therapeutics Inc.
22.28%-27.45%-21.82%-74.56%-47.12%-58.46%-19.25%104.59%-2.40%2.13%
CD
Chaince Digital Holdings Inc
60.97%-27.23%162.69%109.41%-64.75%3.93%85.98%17.14%-93.14%-72.87%

Correlation

The correlation between KPTI and CD is 0.08, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.08

Correlation (3Y)
Calculated over the trailing 3-year period

0.11

Correlation (5Y)
Calculated over the trailing 5-year period

0.07

Correlation (10Y)
Calculated over the trailing 10-year period

0.07

Correlation (All Time)
Calculated using the full available price history since Apr 9, 2015

0.07

Fundamentals

EPS

KPTI:

-$13.00

CD:

-$0.23

PS Ratio

KPTI:

0.89

CD:

303.82

Total Revenue (TTM)

KPTI:

$151.12M

CD:

$1.67M

Gross Profit (TTM)

KPTI:

$145.13M

CD:

-$1.10M

EBITDA (TTM)

KPTI:

-$93.05M

CD:

-$10.65M

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Return for Risk

KPTI vs. CD — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

KPTI
KPTI Risk / Return Rank: 7676
Overall Rank
KPTI Sharpe Ratio Rank: 7676
Sharpe Ratio Rank
KPTI Sortino Ratio Rank: 7878
Sortino Ratio Rank
KPTI Omega Ratio Rank: 7373
Omega Ratio Rank
KPTI Calmar Ratio Rank: 7777
Calmar Ratio Rank
KPTI Martin Ratio Rank: 7878
Martin Ratio Rank

CD
CD Risk / Return Rank: 7070
Overall Rank
CD Sharpe Ratio Rank: 6464
Sharpe Ratio Rank
CD Sortino Ratio Rank: 7878
Sortino Ratio Rank
CD Omega Ratio Rank: 7979
Omega Ratio Rank
CD Calmar Ratio Rank: 6868
Calmar Ratio Rank
CD Martin Ratio Rank: 6060
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

KPTI vs. CD - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Karyopharm Therapeutics Inc. (KPTI) and Chaince Digital Holdings Inc (CD). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


KPTICDDifference
Sharpe ratioReturn per unit of total volatility

+0.51

Sortino ratioReturn per unit of downside risk

0.00

Omega ratioGain probability vs. loss probability

1.25

1.29

-0.04

Calmar ratioReturn relative to maximum drawdown

2.32

1.40

+0.92

Martin ratioReturn relative to average drawdown

5.76

1.91

+3.84

KPTI vs. CD - Sharpe Ratio Comparison

The current KPTI Sharpe Ratio is 1.20, which is higher than the CD Sharpe Ratio of 0.68. The chart below compares the historical Sharpe Ratios of KPTI and CD, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Sharpe Ratios by Period


KPTICDDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

1.20

0.68

+0.51

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

-0.44

0.02

-0.46

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

-0.28

-0.15

-0.13

Sharpe Ratio (All Time)

Calculated using the full available price history

-0.26

-0.18

-0.08

Drawdowns

KPTI vs. CD - Drawdown Comparison

The maximum KPTI drawdown since its inception was -99.50%, roughly equal to the maximum CD drawdown of -99.79%. Use the drawdown chart below to compare losses from any high point for KPTI and CD.


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Drawdown Indicators


KPTICDDifference

Max Drawdown

Largest peak-to-trough decline

-99.50%

-99.79%

+0.29%

Max Drawdown (1Y)

Largest decline over 1 year

-48.36%

-89.83%

+41.47%

Max Drawdown (3Y)

Largest decline over 3 years

-90.08%

-89.83%

-0.25%

Max Drawdown (5Y)

Largest decline over 5 years

-98.36%

-93.02%

-5.34%

Max Drawdown (10Y)

Largest decline over 10 years

-99.15%

-99.58%

+0.43%

Current Drawdown

Current decline from peak

-98.73%

-97.00%

-1.73%

Average Drawdown

Average peak-to-trough decline

-75.26%

-89.96%

+14.70%

Ulcer Index

Depth and duration of drawdowns from previous peaks

19.49%

65.74%

-46.25%

Volatility

KPTI vs. CD - Volatility Comparison

The current volatility for Karyopharm Therapeutics Inc. (KPTI) is 24.41%, while Chaince Digital Holdings Inc (CD) has a volatility of 49.09%. This indicates that KPTI experiences smaller price fluctuations and is considered to be less risky than CD based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


KPTICDDifference

Volatility (1M)

Calculated over the trailing 1-month period

24.41%

49.09%

-24.68%

Volatility (6M)

Calculated over the trailing 6-month period

62.85%

107.71%

-44.86%

Volatility (1Y)

Calculated over the trailing 1-year period

94.09%

185.49%

-91.40%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

94.91%

151.47%

-56.56%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

86.48%

145.86%

-59.38%

Dividends

KPTI vs. CD - Dividend Comparison

Neither KPTI nor CD has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

KPTI vs. CD - Financials Comparison

This section allows you to compare key financial metrics between Karyopharm Therapeutics Inc. and Chaince Digital Holdings Inc. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.0020.00M40.00M60.00M80.00M100.00M120.00M20222023202420252026
35.07M
466.58K
(KPTI) Total Revenue
(CD) Total Revenue
Values in USD except per share items

Frequently Asked Questions


KPTI and CD have a correlation of 0.08, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

CD has higher volatility (49.09%) compared to KPTI (24.41%). In terms of maximum drawdown, KPTI dropped -99.50% vs CD's -99.79%.

KPTI currently has the higher Sharpe Ratio (1.20 vs 0.68), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for KPTI and CD

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