CNTA vs. VSTM

Last updated Apr 2, 2026

Compare and contrast key facts about Centessa Pharmaceuticals Limited (CNTA) and Verastem, Inc. (VSTM).

Performance

CNTA vs. VSTM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Centessa Pharmaceuticals Limited (CNTA) and Verastem, Inc. (VSTM). The values are adjusted to include any dividend payments, if applicable.

CNTA vs. VSTM - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
CNTA Centessa Pharmaceuticals Limited	59.38%	49.31%	110.43%	156.77%	-72.47%	-48.23%
VSTM Verastem, Inc.	-28.11%	49.32%	-36.49%	68.53%	-80.37%	-47.03%

Fundamentals

EPS CNTA : -$1.81 VSTM : -$3.28
PS Ratio CNTA : 355.87 VSTM : 30.53
Total Revenue (TTM) CNTA : $15.00M VSTM : $13.38M
Gross Profit (TTM) CNTA : $15.00M VSTM : $11.26M
EBITDA (TTM) CNTA : -$227.27M VSTM : -$238.93M

Returns By Period

In the year-to-date period, CNTA achieves a 59.38% return, which is significantly higher than VSTM's -28.11% return.

CNTA

• 1D: 0.35%
• 1M: 50.36%
• YTD: 59.38%
• 6M: 76.22%
• 1Y: 201.28%
• 3Y*: 117.95%
• 5Y*: —
• 10Y*: —

VSTM

• 1D: 4.72%
• 1M: -4.64%
• YTD: -28.11%
• 6M: -36.93%
• 1Y: -4.64%
• 3Y*: 3.66%
• 5Y*: -29.42%
• 10Y*: -11.56%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

CNTA vs. VSTM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CNTA

CNTA Risk / Return Rank: 95
CNTA Sharpe Ratio Rank: 95
CNTA Sortino Ratio Rank: 97
CNTA Omega Ratio Rank: 94
CNTA Calmar Ratio Rank: 96
CNTA Martin Ratio Rank: 95

VSTM

VSTM Risk / Return Rank: 39
VSTM Sharpe Ratio Rank: 37
VSTM Sortino Ratio Rank: 43
VSTM Omega Ratio Rank: 42
VSTM Calmar Ratio Rank: 36
VSTM Martin Ratio Rank: 36

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CNTA vs. VSTM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Centessa Pharmaceuticals Limited (CNTA) and Verastem, Inc. (VSTM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	CNTA	VSTM	Difference
Sharpe ratio Return per unit of total volatility	2.82	-0.05	+2.87
Sortino ratio Return per unit of downside risk	3.99	0.56	+3.43
Omega ratio Gain probability vs. loss probability	1.50	1.07	+0.43
Calmar ratio Return relative to maximum drawdown	6.72	-0.14	+6.86
Martin ratio Return relative to average drawdown	16.74	-0.27	+17.01
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

CNTA vs. VSTM - Sharpe Ratio Comparison

The current CNTA Sharpe Ratio is 2.82, which is higher than the VSTM Sharpe Ratio of -0.05. The chart below compares the historical Sharpe Ratios of CNTA and VSTM, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	CNTA	VSTM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	2.82	-0.05	+2.87
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.28	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.12	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.18	-0.22	+0.40

Correlation

The correlation between CNTA and VSTM is 0.24, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

CNTA vs. VSTM - Dividend Comparison

Neither CNTA nor VSTM has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

CNTA vs. VSTM - Drawdown Comparison

The maximum CNTA drawdown since its inception was -88.19%, smaller than the maximum VSTM drawdown of -98.96%. Use the drawdown chart below to compare losses from any high point for CNTA and VSTM.

Drawdown Indicators

	CNTA	VSTM	Difference
Max Drawdown Largest peak-to-trough decline	-88.19%	-98.96%	+10.77%
Max Drawdown (1Y) Largest decline over 1 year	-26.38%	-54.97%	+28.59%
Max Drawdown (5Y) Largest decline over 5 years	—	-96.22%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-98.16%	—
Current Drawdown Current decline from peak	0.00%	-97.37%	+97.37%
Average Drawdown Average peak-to-trough decline	-53.93%	-74.99%	+21.06%
Ulcer Index Depth and duration of drawdowns from previous peaks	10.59%	29.23%	-18.64%

Volatility

CNTA vs. VSTM - Volatility Comparison

Centessa Pharmaceuticals Limited (CNTA) has a higher volatility of 39.77% compared to Verastem, Inc. (VSTM) at 21.39%. This indicates that CNTA's price experiences larger fluctuations and is considered to be riskier than VSTM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CNTA	VSTM	Difference
Volatility (1M) Calculated over the trailing 1-month period	39.77%	21.39%	+18.38%
Volatility (6M) Calculated over the trailing 6-month period	50.29%	55.84%	-5.55%
Volatility (1Y) Calculated over the trailing 1-year period	72.45%	85.82%	-13.37%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	73.65%	105.87%	-32.22%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	73.65%	97.38%	-23.73%

Financials