Amplify Weight Loss Drug & Treatment ETF (THNR) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with THNR. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to THNR
THNR charges 0.59% annually. There are 34 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 2.85B | Oct 2013 | THNR vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 38.66B | Dec 1998 | THNR vs XLV | |
| Vanguard Health Care ETF | 0.10% | 18.50B | Jan 2004 | THNR vs VHT | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 9.98M | Nov 2025 | THNR vs PBPH | |
| Invesco S&P SmallCap Health Care ETF | 0.29% | 131.36M | Apr 2010 | THNR vs PSCH |
Best Risk-Adjusted Alternatives to THNR
THNR has a PortfoliosLab risk / return rank of 16. There are 44 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 90.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 90 | 43.63M | Dec 2014 | THNR vs BBC | |
| SPDR S&P Biotech ETF | 75 | 8.28B | Feb 2006 | THNR vs XBI | |
| ALPS Medical Breakthroughs ETF | 74 | 161.79M | Dec 2014 | THNR vs SBIO | |
| iShares U.S. Pharmaceuticals ETF | 72 | 912.87M | May 2006 | THNR vs IHE | |
| Tema Oncology ETF | 70 | 142.24M | Aug 2023 | THNR vs CANC |
Top Performing THNR Alternatives (YTD)
THNR is at -5.20% YTD. There are 45 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 23.33%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| AdvisorShares Psychedelics ETF | 23.33% | 35.56M | Sep 2021 | THNR vs PSIL | |
| ARK Genomic Revolution Multi-Sector ETF | 17.36% | 1.24B | Oct 2014 | THNR vs ARKG | |
| Roundhill UNH WeeklyPay ETF | 15.01% | 4.48M | Dec 2025 | THNR vs UNHW | |
| iShares Genomics Immunology and Healthcare ETF Gen... | 9.51% | 163.14M | Jun 2019 | THNR vs IDNA | |
| Virtus LifeSci Biotech Clinical Trials ETF | 8.17% | 43.63M | Dec 2014 | THNR vs BBC |
Lowest Volatility Alternatives to THNR
THNR has 19.15% 1-year volatility. There are 31 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Principal Healthcare Innovators Index ETF | 0.00% | 16.16M | Aug 2016 | THNR vs BTEC | |
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | THNR vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | THNR vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.80% | 10.01M | Jun 2007 | THNR vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 10.94% | 14.25M | Jul 2025 | THNR vs XLVI |
Lowest Drawdown Alternatives to THNR
THNR has a 1-year max drawdown of -12.06%. There are 30 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | THNR vs GERM | |
| Horizon Kinetics SPAC Active ETF | -5.30% | 10.01M | Jun 2007 | THNR vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 35.04M | Sep 2016 | THNR vs FTXH | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 67.37M | Jun 2021 | THNR vs IBBQ | |
| iShares U.S. Pharmaceuticals ETF | -8.47% | 912.87M | May 2006 | THNR vs IHE |
Other ETFs from Amplify
The 10 most viewed Amplify ETFs shown here include DIVO, QDVO, IDVO and span 10 categories. AUM among these funds goes as high as $7B.
Often Compared With THNR
Investors most often compare THNR with VOO, XHE, BBH. These 19 comparison targets span 8 categories, based on PortfoliosLab usage data.
Compare THNR with Any Fund or Stock
Compare THNR with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair THNR with funds that move differently
Amplify Weight Loss Drug & Treatment ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to THNR.
Explore THNR Diversifiers