Amplify Weight Loss Drug & Treatment ETF (THNR) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with THNR. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to THNR
THNR charges 0.59% annually. There are 37 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 3.22B | Oct 2013 | THNR vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 42.10B | Dec 1998 | THNR vs XLV | |
| Vanguard Health Care ETF | 0.09% | 20.40B | Jan 2004 | THNR vs VHT | |
| VanEck Healthcare TruSector ETF | 0.10% | 850.50K | Apr 2026 | THNR vs TRUH | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 933.15M | Nov 2025 | THNR vs PBPH |
Best Risk-Adjusted Alternatives to THNR
THNR has a PortfoliosLab risk / return rank of 29. There are 51 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 96 | 47.80M | Dec 2014 | THNR vs BBC | |
| iShares U.S. Pharmaceuticals ETF | 95 | 1.65B | May 2006 | THNR vs IHE | |
| First Trust Nasdaq Pharmaceuticals ETF | 95 | 911.09M | Sep 2016 | THNR vs FTXH | |
| ALPS Medical Breakthroughs ETF | 95 | 201.57M | Dec 2014 | THNR vs SBIO | |
| Invesco Dynamic Pharmaceuticals ETF | 94 | 472.10M | Jun 2005 | THNR vs PJP |
Top Performing THNR Alternatives (YTD)
THNR is at 0.29% YTD. There are 55 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 36.76%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| ARK Genomic Revolution Multi-Sector ETF | 36.76% | 1.73B | Oct 2014 | THNR vs ARKG | |
| AdvisorShares Psychedelics ETF | 36.69% | 48.53M | Sep 2021 | THNR vs PSIL | |
| Roundhill UNH WeeklyPay ETF | 28.89% | 7.27M | Dec 2025 | THNR vs UNHW | |
| Virtus LifeSci Biotech Clinical Trials ETF | 27.03% | 47.80M | Dec 2014 | THNR vs BBC | |
| SPDR S&P Health Care Services ETF | 25.67% | 206.72M | Sep 2011 | THNR vs XHS |
Lowest Volatility Alternatives to THNR
THNR has 18.92% 1-year volatility. There are 30 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | THNR vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | THNR vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.66% | 10.09M | Jun 2007 | THNR vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 10.75% | 21.55M | Jul 2025 | THNR vs XLVI | |
| Milliman Healthcare Inflation Plus ETF | 10.92% | 982.35K | Apr 2026 | THNR vs MHIP |
Lowest Drawdown Alternatives to THNR
THNR has a 1-year max drawdown of -12.06%. There are 32 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | THNR vs GERM | |
| Horizon Kinetics SPAC Active ETF | -4.20% | 10.09M | Jun 2007 | THNR vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 911.09M | Sep 2016 | THNR vs FTXH | |
| State Street Health Care Select Sector SPDR Premiu... | -8.14% | 21.55M | Jul 2025 | THNR vs XLVI | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 75.06M | Jun 2021 | THNR vs IBBQ |
Other ETFs from Amplify
The 10 most viewed Amplify ETFs shown here include DIVO, QDVO, IDVO and span 12 categories. AUM among these funds goes as high as $8B.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| Amplify CWP Enhanced Dividend Income ETF | Derivative Income | 84 | 8.84% | 7.58B | Dec 2016 | THNR vs DIVO | |
| Amplify CWP Growth & Income ETF | Derivative Income | 52 | 7.82% | 723.80M | Aug 2024 | THNR vs QDVO | |
| Amplify CWP International Enhanced Dividend Income... | Derivative Income, Dividend, Foreign Large Cap Equities | 86 | 15.22% | 1.35B | Sep 2022 | THNR vs IDVO | |
| Amplify Junior Silver Miners ETF | Silver, Precious Metals | 47 | -10.26% | 3.28B | Nov 2012 | THNR vs SILJ | |
| Amplify Blockchain Technology ETF | Blockchain, Technology Equities | 17 | 7.85% | 1.06B | Jan 2018 | THNR vs BLOK | |
| Amplify Cybersecurity ETF | Technology Equities, Cybersecurity | 43 | 36.43% | 2.69B | Nov 2014 | THNR vs HACK | |
| Amplify AI Powered Equity ETF | Large Cap Growth Equities | 60 | 11.16% | 119.27M | Oct 2017 | THNR vs AIEQ | |
| Breakwave Tanker Shipping ETF | Commodities | 99 | 1,246.34% | 35.89M | May 2023 | THNR vs BWET | |
| Amplify CEF High Income ETF | Diversified Portfolio | 44 | 5.58% | 727.74M | Jun 2012 | THNR vs YYY | |
| Amplify Lithium & Battery Technology ETF | Lithium & Battery Metals | 58 | 4.71% | 116.20M | Jun 2018 | THNR vs BATT |
Often Compared With THNR
Investors most often compare THNR with BAGY, IBRN, CANC. These 20 comparison targets span 9 categories, based on PortfoliosLab usage data.
Compare THNR with Any Fund or Stock
Compare THNR with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair THNR with funds that move differently
Amplify Weight Loss Drug & Treatment ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to THNR.
Explore THNR Diversifiers