THNR vs. PBPH

Last updated Jun 3, 2026

THNR (Amplify Weight Loss Drug & Treatment ETF) and PBPH (Portfolio Building Block World Pharma and Biotech Index ETF) are both Health & Biotech Equities funds - THNR tracks the VettaFi Weight Loss Drug & Treatment Index while PBPH tracks the BITA Global Pharma and Biotech Select Index. Both are passively managed. Their correlation of 0.87 suggests significant overlap in exposure. THNR charges 0.59%/yr vs 0.13%/yr for PBPH.

Performance

THNR vs. PBPH - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Amplify Weight Loss Drug & Treatment ETF (THNR) and Portfolio Building Block World Pharma and Biotech Index ETF (PBPH). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, THNR achieves a -5.20% return, which is significantly lower than PBPH's -1.70% return.

THNR

• 1D: -1.47%
• 1M: -2.91%
• YTD: -5.20%
• 6M: -3.73%
• 1Y: 9.10%
• 3Y*: —
• 5Y*: —
• 10Y*: —

PBPH

• 1D: -1.15%
• 1M: -0.61%
• YTD: -1.70%
• 6M: 0.14%
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

THNR vs. PBPH - Yearly Performance Comparison

	2026 (YTD)	2025
THNR Amplify Weight Loss Drug & Treatment ETF	-5.20%	-1.35%
PBPH Portfolio Building Block World Pharma and Biotech Index ETF	-1.70%	0.76%

Correlation

The correlation between THNR and PBPH is 0.87, indicating a strong positive relationship between their price movements. Combining them offers limited diversification - they tend to fall together during downturns.

	Correlation
Correlation (All Time) Calculated using the full available price history since Nov 26, 2025	0.87

Return for Risk

THNR vs. PBPH — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

THNR

THNR Risk / Return Rank: 16
THNR Sharpe Ratio Rank: 15
THNR Sortino Ratio Rank: 16
THNR Omega Ratio Rank: 15
THNR Calmar Ratio Rank: 18
THNR Martin Ratio Rank: 17

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

THNR vs. PBPH - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Amplify Weight Loss Drug & Treatment ETF (THNR) and Portfolio Building Block World Pharma and Biotech Index ETF (PBPH). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	THNR	PBPH	Difference
Sharpe ratio Return per unit of total volatility	0.48	—	—
Sortino ratio Return per unit of downside risk	0.81	—	—
Omega ratio Gain probability vs. loss probability	1.10	—	—
Calmar ratio Return relative to maximum drawdown	0.76	—	—
Martin ratio Return relative to average drawdown	1.75	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	THNR	PBPH	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.48	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.09	-0.11	+0.02

Drawdowns

THNR vs. PBPH - Drawdown Comparison

The maximum THNR drawdown since its inception was -32.51%, which is greater than PBPH's maximum drawdown of -11.10%. Use the drawdown chart below to compare losses from any high point for THNR and PBPH.

Drawdown Indicators

	THNR	PBPH	Difference
Max Drawdown Largest peak-to-trough decline	-32.51%	-11.10%	-21.41%
Max Drawdown (1Y) Largest decline over 1 year	-12.06%	—	—
Current Drawdown Current decline from peak	-13.00%	-9.22%	-3.78%
Average Drawdown Average peak-to-trough decline	-12.24%	-4.20%	-8.04%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.26%	—	—

Volatility

Volatility by Period

	THNR	PBPH	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.16%	—	—
Volatility (6M) Calculated over the trailing 6-month period	13.55%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	19.15%	16.83%	+2.32%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	19.37%	16.83%	+2.54%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	19.37%	16.83%	+2.54%

THNR vs. PBPH - Expense Ratio Comparison

THNR has a 0.59% expense ratio, which is higher than PBPH's 0.13% expense ratio.

Dividends

THNR vs. PBPH - Dividend Comparison

THNR's dividend yield for the trailing twelve months is around 1.73%, more than PBPH's 0.09% yield.

Position	TTM	2025	2024
PBPH Portfolio Building Block World Pharma and Biotech Index ETF	0.09%	0.09%	0.00%
THNR Amplify Weight Loss Drug & Treatment ETF	1.73%	1.64%	0.98%

Frequently Asked Questions

Can I hold both THNR and PBPH in my portfolio?

THNR and PBPH have a correlation of 0.87, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, THNR or PBPH?

On fees, PBPH is cheaper at 0.13% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, THNR or PBPH?

PBPH is cheaper with a 0.13% expense ratio, compared with 0.59% for THNR.

Which ETF pays a higher dividend yield, THNR or PBPH?

THNR has the higher dividend yield at 1.73%, compared with 0.09% for PBPH.

What is the main difference between THNR and PBPH?

THNR tracks VettaFi Weight Loss Drug & Treatment Index, while PBPH tracks BITA Global Pharma and Biotech Select Index. They also come from different issuers: Amplify and Portfolio Building Block. Their fees differ too: 0.59% for THNR and 0.13% for PBPH.