THNR vs. GSKH

Last updated Jun 21, 2026

THNR (Amplify Weight Loss Drug & Treatment ETF) and GSKH (GSK plc ADRhedged ETF) are both Health & Biotech Equities funds - THNR tracks the VettaFi Weight Loss Drug & Treatment Index while GSKH tracks the GSK plc Local Shares Total Return. Both are passively managed. Over the past year, THNR returned 7.44% vs 39.42% for GSKH. At a 0.45 correlation, their price movements are largely independent. THNR charges 0.59%/yr vs 0.19%/yr for GSKH.

Performance

THNR vs. GSKH - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Amplify Weight Loss Drug & Treatment ETF (THNR) and GSK plc ADRhedged ETF (GSKH). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, THNR achieves a -4.38% return, which is significantly lower than GSKH's 7.33% return.

THNR

• 1D: -0.59%
• 1M: -1.69%
• YTD: -4.38%
• 6M: -3.81%
• 1Y: 7.44%
• 3Y*: —
• 5Y*: —
• 10Y*: —

GSKH

• 1D: -1.73%
• 1M: 0.17%
• YTD: 7.33%
• 6M: 7.39%
• 1Y: 39.42%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

THNR vs. GSKH - Yearly Performance Comparison

	2026 (YTD)	2025
THNR Amplify Weight Loss Drug & Treatment ETF	-4.38%	13.55%
GSKH GSK plc ADRhedged ETF	7.33%	36.51%

Correlation

The correlation between THNR and GSKH is 0.42, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.42
Correlation (All Time) Calculated using the full available price history since Jan 7, 2025	0.45

Return for Risk

THNR vs. GSKH — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

THNR

THNR Risk / Return Rank: 14
THNR Sharpe Ratio Rank: 13
THNR Sortino Ratio Rank: 13
THNR Omega Ratio Rank: 13
THNR Calmar Ratio Rank: 15
THNR Martin Ratio Rank: 14

GSKH

GSKH Risk / Return Rank: 41
GSKH Sharpe Ratio Rank: 41
GSKH Sortino Ratio Rank: 44
GSKH Omega Ratio Rank: 42
GSKH Calmar Ratio Rank: 41
GSKH Martin Ratio Rank: 36

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

THNR vs. GSKH - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Amplify Weight Loss Drug & Treatment ETF (THNR) and GSK plc ADRhedged ETF (GSKH). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	THNR	GSKH	Difference
Sharpe ratio: Return per unit of total volatility	0.35	1.41	-1.06
Sortino ratio: Return per unit of downside risk	0.65	2.14	-1.49
Omega ratio: Gain probability vs. loss probability	1.08	1.27	-0.19
Calmar ratio: Return relative to maximum drawdown	0.56	1.99	-1.43
Martin ratio: Return relative to average drawdown	1.23	5.27	-4.04

THNR vs. GSKH - Sharpe Ratio Comparison

The current THNR Sharpe Ratio is 0.35, which is lower than the GSKH Sharpe Ratio of 1.41. The chart below compares the historical Sharpe Ratios of THNR and GSKH, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

THNR vs. GSKH - Drawdown Comparison

The maximum THNR drawdown since its inception was -32.51%, which is greater than GSKH's maximum drawdown of -18.54%. Use the drawdown chart below to compare losses from any high point for THNR and GSKH.

Drawdown Indicators

	THNR	GSKH	Difference
Max Drawdown Largest peak-to-trough decline	-32.51%	-18.54%	-13.97%
Max Drawdown (1Y) Largest decline over 1 year	-12.06%	-18.54%	+6.48%
Current Drawdown Current decline from peak	-12.25%	-13.70%	+1.45%
Average Drawdown Average peak-to-trough decline	-12.22%	-5.82%	-6.40%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.44%	6.98%	-1.54%

Volatility

THNR vs. GSKH - Volatility Comparison

The current volatility for Amplify Weight Loss Drug & Treatment ETF (THNR) is 5.65%, while GSK plc ADRhedged ETF (GSKH) has a volatility of 6.48%. This indicates that THNR experiences smaller price fluctuations and is considered to be less risky than GSKH based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	THNR	GSKH	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.65%	6.48%	-0.83%
Volatility (6M) Calculated over the trailing 6-month period	13.63%	18.48%	-4.85%
Volatility (1Y) Calculated over the trailing 1-year period	18.99%	26.20%	-7.21%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	19.34%	26.92%	-7.58%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	19.34%	26.92%	-7.58%

THNR vs. GSKH - Expense Ratio Comparison

THNR has a 0.59% expense ratio, which is higher than GSKH's 0.19% expense ratio.

Dividends

THNR vs. GSKH - Dividend Comparison

THNR's dividend yield for the trailing twelve months is around 1.71%, less than GSKH's 2.89% yield.

Position	TTM	2025	2024
GSKH GSK plc ADRhedged ETF	2.89%	1.15%	0.00%
THNR Amplify Weight Loss Drug & Treatment ETF	1.71%	1.64%	0.98%

Frequently Asked Questions

Can I hold both THNR and GSKH in my portfolio?

THNR and GSKH have a correlation of 0.42, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, THNR or GSKH?

GSKH has higher volatility (6.48%) compared to THNR (5.65%). In terms of maximum drawdown, THNR dropped -32.51% vs GSKH's -18.54%.

Which ETF is better, THNR or GSKH?

On 1-year performance, GSKH leads with 39.42% vs 7.44% for THNR. On fees, GSKH is cheaper at 0.19% per year. On volatility, THNR has been the lower-risk option at 5.65%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, THNR or GSKH?

Over the 1-year period, GSKH has performed better with a 39.42% return vs 7.44%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, THNR or GSKH?

GSKH is cheaper with a 0.19% expense ratio, compared with 0.59% for THNR.

Which ETF pays a higher dividend yield, THNR or GSKH?

GSKH has the higher dividend yield at 2.89%, compared with 1.71% for THNR.

What is the main difference between THNR and GSKH?

THNR tracks VettaFi Weight Loss Drug & Treatment Index, while GSKH tracks GSK plc Local Shares Total Return. They also come from different issuers: Amplify and ADRhedged. Their fees differ too: 0.59% for THNR and 0.19% for GSKH.

Which has better risk-adjusted returns?

GSKH currently has the higher Sharpe Ratio (1.41 vs 0.35), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.