IONS vs. VOO

In the year-to-date period, IONS achieves a -4.15% return, which is significantly lower than VOO's 0.90% return. Over the past 10 years, IONS has underperformed VOO with an annualized return of -6.60%, while VOO has yielded a comparatively higher 12.81% annualized return.

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This table presents a comparison of risk-adjusted performance metrics for Ionis Pharmaceuticals, Inc. (IONS) and Vanguard S&P 500 ETF (VOO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

The current IONS Sharpe Ratio is -0.20, which is lower than the VOO Sharpe Ratio of 0.74. The chart below compares the historical Sharpe Ratios of IONS and VOO, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

IONS has not paid dividends to shareholders, while VOO's dividend yield for the trailing twelve months is around 1.29%.

The maximum IONS drawdown since its inception was -91.72%, which is greater than VOO's maximum drawdown of -33.99%. Use the drawdown chart below to compare losses from any high point for IONS and VOO.

Ionis Pharmaceuticals, Inc. (IONS) has a higher volatility of 11.73% compared to Vanguard S&P 500 ETF (VOO) at 4.84%. This indicates that IONS's price experiences larger fluctuations and is considered to be riskier than VOO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.