PortfoliosLab logoPortfoliosLab logo
IONS vs. QBTS
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

IONS vs. QBTS - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Ionis Pharmaceuticals, Inc. (IONS) and D-Wave Quantum Inc (QBTS). The values are adjusted to include any dividend payments, if applicable.

Loading charts...

Returns By Period

In the year-to-date period, IONS achieves a -34.56% return, which is significantly lower than QBTS's -30.86% return.


IONS

1D
-2.83%
1M
-36.71%
6M
-37.38%
YTD
-34.56%
1Y
20.31%
3Y*
7.90%
5Y*
6.87%
10Y*
3.21%
ALL TIME*
5.06%

QBTS

1D
0.56%
1M
-19.75%
6M
-14.80%
YTD
-30.86%
1Y
10.38%
3Y*
88.49%
5Y*
10Y*
ALL TIME*
19.23%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison


PositionAvg. Volume Value (2W)Avg. Volume Value (1M)Avg. Volume Value (3M)
$189.49M$272.86M$184.93M
$359.00M$350.88M$734.73M

IONS vs. QBTS - Yearly Performance Comparison


2026 (YTD)2025202420232022
IONS
Ionis Pharmaceuticals, Inc.
-34.56%126.29%-30.90%33.94%-17.35%
QBTS
D-Wave Quantum Inc
-30.86%211.31%854.44%-38.88%-83.96%

Correlation

The correlation between IONS and QBTS is 0.17, which is low. Their historical price movements had little consistent relationship.


Correlation
Correlation (1Y)
Focuses on recent behavior, but can change the most.

0.17

Correlation (3Y)
Balances recent behavior with more history.

0.15

Correlation (All Time)
Calculated using the full available price history since Aug 8, 2022

0.15

Fundamentals

Market Cap

IONS:

$8.60B

QBTS:

$6.64B

EPS

IONS:

-$3.46

QBTS:

-$1.04

PS Ratio

IONS:

9.67

QBTS:

514.63

PB Ratio

IONS:

19.47

QBTS:

5.91

Total Revenue (TTM)

IONS:

$873.76M

QBTS:

$12.44M

Gross Profit (TTM)

IONS:

$857.70M

QBTS:

$8.25M

EBITDA (TTM)

IONS:

$4.33B

QBTS:

-$399.03M

Compare stocks, funds, or ETFs

Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.


Return for Risk

IONS vs. QBTS — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

IONS
IONS Risk / Return Rank: 6060
Overall Rank
IONS Sharpe Ratio Rank: 5959
Sharpe Ratio Rank
IONS Sortino Ratio Rank: 5858
Sortino Ratio Rank
IONS Omega Ratio Rank: 6464
Omega Ratio Rank
IONS Calmar Ratio Rank: 5858
Calmar Ratio Rank
IONS Martin Ratio Rank: 6262
Martin Ratio Rank

QBTS
QBTS Risk / Return Rank: 5050
Overall Rank
QBTS Sharpe Ratio Rank: 4646
Sharpe Ratio Rank
QBTS Sortino Ratio Rank: 5858
Sortino Ratio Rank
QBTS Omega Ratio Rank: 5353
Omega Ratio Rank
QBTS Calmar Ratio Rank: 4747
Calmar Ratio Rank
QBTS Martin Ratio Rank: 4646
Martin Ratio Rank
The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

IONS vs. QBTS - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Ionis Pharmaceuticals, Inc. (IONS) and D-Wave Quantum Inc (QBTS). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


IONSQBTSDifference
Sharpe ratioReturn per unit of total volatility

+0.34

Sortino ratioReturn per unit of downside risk

+0.02

Omega ratioGain probability vs. loss probability

1.16

1.10

+0.06

Calmar ratioReturn relative to maximum drawdown

0.51

0.07

+0.44

Martin ratioReturn relative to average drawdown

1.64

0.12

+1.52

IONS vs. QBTS - Sharpe Ratio Comparison

The current IONS Sharpe Ratio is 0.39, which is higher than the QBTS Sharpe Ratio of 0.05. The chart below compares the historical Sharpe Ratios of IONS and QBTS, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


Loading charts...

Drawdowns

IONS vs. QBTS - Drawdown Comparison

The maximum IONS drawdown since its inception was -91.42%, smaller than the maximum QBTS drawdown of -96.67%. Use the drawdown chart below to compare losses from any high point for IONS and QBTS.


Loading charts...

Drawdown Indicators


IONSQBTSDifference

Max Drawdown

Largest peak-to-trough decline

-91.42%

-96.67%

+5.25%

Max Drawdown (1Y)

Largest decline over 1 year

-40.15%

-71.01%

+30.86%

Max Drawdown (3Y)

Largest decline over 3 years

-52.36%

-71.01%

+18.65%

Max Drawdown (5Y)

Largest decline over 5 years

-52.36%

Max Drawdown (10Y)

Largest decline over 10 years

-70.39%

Current Drawdown

Current decline from peak

-40.15%

-59.62%

+19.47%

Average Drawdown

Average peak-to-trough decline

-52.26%

-65.27%

+13.01%

Ulcer Index

Depth and duration of drawdowns from previous peaks

12.53%

44.79%

-32.26%

Volatility

IONS vs. QBTS - Volatility Comparison

Ionis Pharmaceuticals, Inc. (IONS) and D-Wave Quantum Inc (QBTS) have volatilities of 29.82% and 30.87%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.


Loading charts...

Volatility by Period


IONSQBTSDifference

Volatility (1M)

Calculated over the trailing 1-month period

29.82%

30.87%

-1.05%

Volatility (6M)

Calculated over the trailing 6-month period

35.47%

77.01%

-41.54%

Volatility (1Y)

Calculated over the trailing 1-year period

52.79%

110.95%

-58.16%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

43.75%

149.71%

-105.96%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

45.64%

149.71%

-104.07%

Dividends

IONS vs. QBTS - Dividend Comparison

Neither IONS nor QBTS has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

IONS vs. QBTS - Financials Comparison

This section allows you to compare key financial metrics between Ionis Pharmaceuticals, Inc. and D-Wave Quantum Inc. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items

Frequently Asked Questions


IONS and QBTS have a correlation of 0.17, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

QBTS has higher volatility (30.87%) compared to IONS (29.82%). In terms of maximum drawdown, IONS dropped -91.42% vs QBTS's -96.67%.

IONS currently has the higher Sharpe Ratio (0.39 vs 0.05), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for IONS and QBTS

Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.

Open Portfolio Optimizer