IGF vs. SBIO

Last updated Jun 9, 2026

IGF (iShares Global Infrastructure ETF) and SBIO (ALPS Medical Breakthroughs ETF) are both exchange-traded funds - IGF is a Industrials Equities fund tracking the S&P Global Infrastructure Index, while SBIO is a Health & Biotech Equities fund tracking the S-Network Medical Breakthroughs Index. Both are passively managed. Over the past 10 years, IGF returned 8.26%/yr vs 8.36%/yr for SBIO. At a 0.36 correlation, their price movements are largely independent. IGF charges 0.39%/yr vs 0.50%/yr for SBIO.

Performance

IGF vs. SBIO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in iShares Global Infrastructure ETF (IGF) and ALPS Medical Breakthroughs ETF (SBIO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, IGF achieves a 7.07% return, which is significantly higher than SBIO's -1.72% return. Both investments have delivered pretty close results over the past 10 years, with IGF having a 8.26% annualized return and SBIO not far ahead at 8.36%.

IGF

• 1D: -0.73%
• 1M: -1.91%
• YTD: 7.07%
• 6M: 8.23%
• 1Y: 13.89%
• 3Y*: 15.43%
• 5Y*: 9.75%
• 10Y*: 8.26%

SBIO

• 1D: -0.36%
• 1M: -9.33%
• YTD: -1.72%
• 6M: -2.48%
• 1Y: 59.38%
• 3Y*: 16.69%
• 5Y*: 1.33%
• 10Y*: 8.36%

*Multi-year figures are annualized to reflect compound growth (CAGR)

IGF vs. SBIO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
IGF iShares Global Infrastructure ETF	7.07%	21.31%	14.81%	6.14%	-1.26%	11.57%	-6.50%	25.82%	-9.95%	19.31%
SBIO ALPS Medical Breakthroughs ETF	-1.72%	55.07%	3.81%	8.68%	-28.08%	-17.55%	21.17%	50.30%	-11.81%	45.67%

Correlation

The correlation between IGF and SBIO is 0.27, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.27
Correlation (3Y) Calculated over the trailing 3-year period	0.32
Correlation (5Y) Calculated over the trailing 5-year period	0.37
Correlation (10Y) Calculated over the trailing 10-year period	0.37
Correlation (All Time) Calculated using the full available price history since Jan 2, 2015	0.36

IGF vs. SBIO - Sectors Allocation Comparison

Sectors	IGF	SBIO
Utilities	41.1%	-
Industrials	38.8%	-
Energy	20.1%	-
Real Estate	0.1%	-
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Financial Services	-	-0.0%
Healthcare	-	100.0%
Technology	-	-

Return for Risk

IGF vs. SBIO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IGF

IGF Risk / Return Rank: 45
IGF Sharpe Ratio Rank: 42
IGF Sortino Ratio Rank: 41
IGF Omega Ratio Rank: 40
IGF Calmar Ratio Rank: 53
IGF Martin Ratio Rank: 47

SBIO

SBIO Risk / Return Rank: 73
SBIO Sharpe Ratio Rank: 69
SBIO Sortino Ratio Rank: 70
SBIO Omega Ratio Rank: 60
SBIO Calmar Ratio Rank: 88
SBIO Martin Ratio Rank: 78

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

IGF vs. SBIO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for iShares Global Infrastructure ETF (IGF) and ALPS Medical Breakthroughs ETF (SBIO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	IGF	SBIO	Difference
Sharpe ratio: Return per unit of total volatility	1.32	2.02	-0.70
Sortino ratio: Return per unit of downside risk	1.91	2.85	-0.93
Omega ratio: Gain probability vs. loss probability	1.23	1.33	-0.09
Calmar ratio: Return relative to maximum drawdown	2.38	4.72	-2.34
Martin ratio: Return relative to average drawdown	7.08	13.54	-6.47
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

IGF vs. SBIO - Sharpe Ratio Comparison

The current IGF Sharpe Ratio is 1.32, which is lower than the SBIO Sharpe Ratio of 2.02. The chart below compares the historical Sharpe Ratios of IGF and SBIO, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	IGF	SBIO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.32	2.02	-0.70
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.70	0.04	+0.66
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.49	0.25	+0.24
Sharpe Ratio (All Time) Calculated using the full available price history	0.23	0.21	+0.02

Drawdowns

IGF vs. SBIO - Drawdown Comparison

The maximum IGF drawdown since its inception was -58.33%, smaller than the maximum SBIO drawdown of -63.06%. Use the drawdown chart below to compare losses from any high point for IGF and SBIO.

Drawdown Indicators

	IGF	SBIO	Difference
Max Drawdown Largest peak-to-trough decline	-58.33%	-63.06%	+4.73%
Max Drawdown (1Y) Largest decline over 1 year	-5.87%	-12.66%	+6.79%
Max Drawdown (3Y) Largest decline over 3 years	-14.28%	-42.44%	+28.16%
Max Drawdown (5Y) Largest decline over 5 years	-20.83%	-53.10%	+32.27%
Max Drawdown (10Y) Largest decline over 10 years	-42.11%	-63.06%	+20.95%
Current Drawdown Current decline from peak	-5.29%	-17.90%	+12.61%
Average Drawdown Average peak-to-trough decline	-11.87%	-28.43%	+16.56%
Ulcer Index Depth and duration of drawdowns from previous peaks	1.97%	4.40%	-2.43%

Volatility

IGF vs. SBIO - Volatility Comparison

The current volatility for iShares Global Infrastructure ETF (IGF) is 3.61%, while ALPS Medical Breakthroughs ETF (SBIO) has a volatility of 9.87%. This indicates that IGF experiences smaller price fluctuations and is considered to be less risky than SBIO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IGF	SBIO	Difference
Volatility (1M) Calculated over the trailing 1-month period	3.61%	9.87%	-6.26%
Volatility (6M) Calculated over the trailing 6-month period	8.68%	22.68%	-14.00%
Volatility (1Y) Calculated over the trailing 1-year period	10.56%	29.62%	-19.06%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	14.00%	33.56%	-19.56%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	16.84%	33.18%	-16.34%

IGF vs. SBIO - Expense Ratio Comparison

IGF has a 0.39% expense ratio, which is lower than SBIO's 0.50% expense ratio.

Dividends

IGF vs. SBIO - Dividend Comparison

IGF's dividend yield for the trailing twelve months is around 3.01%, while SBIO has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
IGF iShares Global Infrastructure ETF	3.01%	3.23%	3.21%	3.36%	2.67%	2.42%	2.33%	3.27%	3.52%	2.95%	2.98%	3.25%
SBIO ALPS Medical Breakthroughs ETF	0.00%	0.00%	3.55%	0.22%	0.00%	0.00%	0.00%	0.04%	2.79%	1.77%	0.00%	0.00%

Frequently Asked Questions

Can I hold both IGF and SBIO in my portfolio?

IGF and SBIO have a correlation of 0.27, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, IGF or SBIO?

SBIO has higher volatility (9.87%) compared to IGF (3.61%). In terms of maximum drawdown, IGF dropped -58.33% vs SBIO's -63.06%.

Which ETF is better, IGF or SBIO?

On 10-year performance, SBIO leads with 8.36% vs 8.26% for IGF. On fees, IGF is cheaper at 0.39% per year. On volatility, IGF has been the lower-risk option at 3.61%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, IGF or SBIO?

Over the 10-year period, SBIO has performed better with a 8.36% return vs 8.26%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, IGF or SBIO?

IGF is cheaper with a 0.39% expense ratio, compared with 0.50% for SBIO.

Which ETF pays a higher dividend yield, IGF or SBIO?

IGF has the higher dividend yield at 3.01%, compared with 0.00% for SBIO.

What is the main difference between IGF and SBIO?

IGF is categorized as Industrials Equities, while SBIO is Health & Biotech Equities. IGF tracks S&P Global Infrastructure Index, while SBIO tracks S-Network Medical Breakthroughs Index. They also come from different issuers: iShares and SS&C. Their fees differ too: 0.39% for IGF and 0.50% for SBIO.

Which has better risk-adjusted returns?

SBIO currently has the higher Sharpe Ratio (2.02 vs 1.32), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.