BBP vs. XLVI

Last updated Jun 24, 2026

BBP (Virtus LifeSci Biotech Products ETF) and XLVI (State Street Health Care Select Sector SPDR Premium Income ETF) are both exchange-traded funds - BBP is a Health & Biotech Equities fund tracking the LifeSci Biotechnology Products Index, while XLVI is a Derivative Income fund actively managed by State Street. BBP is passively managed, while XLVI is actively managed. A 0.53 correlation means they provide meaningful diversification when combined. BBP charges 0.79%/yr vs 0.35%/yr for XLVI.

Performance

BBP vs. XLVI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Virtus LifeSci Biotech Products ETF (BBP) and State Street Health Care Select Sector SPDR Premium Income ETF (XLVI). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, BBP achieves a 16.04% return, which is significantly higher than XLVI's 2.50% return.

BBP

• 1D: 1.20%
• 1M: 7.69%
• YTD: 16.04%
• 6M: 14.38%
• 1Y: 59.95%
• 3Y*: 20.40%
• 5Y*: 11.34%
• 10Y*: 13.69%

XLVI

• 1D: 1.53%
• 1M: 2.15%
• YTD: 2.50%
• 6M: 2.57%
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

BBP vs. XLVI - Yearly Performance Comparison

	2026 (YTD)	2025
BBP Virtus LifeSci Biotech Products ETF	16.04%	29.32%
XLVI State Street Health Care Select Sector SPDR Premium Income ETF	2.50%	12.41%

Correlation

The correlation between BBP and XLVI is 0.53, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (All Time) Calculated using the full available price history since Jul 30, 2025	0.53

BBP vs. XLVI - Sectors Allocation Comparison

Sectors	BBP	XLVI
Healthcare	100.0%	100.0%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	100.2%
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

BBP vs. XLVI — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

BBP

BBP Risk / Return Rank: 85
BBP Sharpe Ratio Rank: 84
BBP Sortino Ratio Rank: 82
BBP Omega Ratio Rank: 73
BBP Calmar Ratio Rank: 94
BBP Martin Ratio Rank: 91

XLVI

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

BBP vs. XLVI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Virtus LifeSci Biotech Products ETF (BBP) and State Street Health Care Select Sector SPDR Premium Income ETF (XLVI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	BBP	XLVI	Difference
Sharpe ratio: Return per unit of total volatility	2.52	—	—
Sortino ratio: Return per unit of downside risk	3.42	—	—
Omega ratio: Gain probability vs. loss probability	1.40	—	—
Calmar ratio: Return relative to maximum drawdown	6.49	—	—
Martin ratio: Return relative to average drawdown	20.18	—	—

Drawdowns

BBP vs. XLVI - Drawdown Comparison

The maximum BBP drawdown since its inception was -44.32%, which is greater than XLVI's maximum drawdown of -8.14%. Use the drawdown chart below to compare losses from any high point for BBP and XLVI.

Drawdown Indicators

	BBP	XLVI	Difference
Max Drawdown Largest peak-to-trough decline	-44.32%	-8.14%	-36.18%
Max Drawdown (1Y) Largest decline over 1 year	-9.28%	—	—
Max Drawdown (3Y) Largest decline over 3 years	-26.09%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-37.89%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-44.32%	—	—
Current Drawdown Current decline from peak	0.00%	-0.97%	+0.97%
Average Drawdown Average peak-to-trough decline	-11.98%	-1.94%	-10.04%
Ulcer Index Depth and duration of drawdowns from previous peaks	2.98%	—	—

Volatility

Volatility by Period

	BBP	XLVI	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.46%	—	—
Volatility (6M) Calculated over the trailing 6-month period	18.88%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	23.96%	11.06%	+12.90%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	26.37%	11.06%	+15.31%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	27.39%	11.06%	+16.33%

BBP vs. XLVI - Expense Ratio Comparison

BBP has a 0.79% expense ratio, which is higher than XLVI's 0.35% expense ratio.

Dividends

BBP vs. XLVI - Dividend Comparison

BBP has not paid dividends to shareholders, while XLVI's dividend yield for the trailing twelve months is around 11.17%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
BBP Virtus LifeSci Biotech Products ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.18%	0.00%	1.29%
XLVI State Street Health Care Select Sector SPDR Premium Income ETF	11.17%	5.73%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both BBP and XLVI in my portfolio?

BBP and XLVI have a correlation of 0.53, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, BBP or XLVI?

On fees, XLVI is cheaper at 0.35% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, BBP or XLVI?

XLVI is cheaper with a 0.35% expense ratio, compared with 0.79% for BBP.

Which ETF pays a higher dividend yield, BBP or XLVI?

XLVI has the higher dividend yield at 11.17%, compared with 0.00% for BBP.

What is the main difference between BBP and XLVI?

BBP is categorized as Health & Biotech Equities, while XLVI is Derivative Income. They also come from different issuers: Virtus Investment Partners and State Street. Their fees differ too: 0.79% for BBP and 0.35% for XLVI.