XLVI vs. TMED

Last updated Aug 2, 2026

XLVI (State Street Health Care Select Sector SPDR Premium Income ETF) and TMED (T. Rowe Price Health Care ETF) are both exchange-traded funds - XLVI is a Derivative Income fund actively managed by State Street, while TMED is a Health & Biotech Equities fund actively managed by T. Rowe Price. Both are actively managed. Over the past year, XLVI returned 23.20% vs 41.29% for TMED. Their correlation of 0.84 means they have usually moved in the same direction. XLVI charges 0.35%/yr vs 0.44%/yr for TMED.

Performance

XLVI vs. TMED - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in State Street Health Care Select Sector SPDR Premium Income ETF (XLVI) and T. Rowe Price Health Care ETF (TMED). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, XLVI achieves a 7.10% return, which is significantly lower than TMED's 13.99% return.

XLVI

• 1D: -0.18%
• 1M: 1.17%
• 6M: 6.83%
• YTD: 7.10%
• 1Y: 23.20%
• 3Y*: —
• 5Y*: —
• 10Y*: —
• ALL TIME*: 20.35%

TMED

• 1D: -0.97%
• 1M: -3.17%
• 6M: 14.67%
• YTD: 13.99%
• 1Y: 41.29%
• 3Y*: —
• 5Y*: —
• 10Y*: —
• ALL TIME*: 31.33%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
TMED T. Rowe Price Health Care ETF	$582.74K	$386.19K	$172.00K
XLVI State Street Health Care Select Sector SPDR Premium Income ETF	$951.77K	$684.72K	$477.94K

XLVI vs. TMED - Yearly Performance Comparison

	2026 (YTD)	2025
XLVI State Street Health Care Select Sector SPDR Premium Income ETF	7.10%	12.41%
TMED T. Rowe Price Health Care ETF	13.99%	21.72%

Correlation

The correlation between XLVI and TMED is 0.84, meaning they have usually moved in the same direction, including during past declines.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.84
Correlation (All Time) Calculated using the full available price history since Jul 30, 2025	0.84

The correlation between XLVI and TMED has been stable across timeframes, ranging from 0.84 to 0.84 - a consistent structural relationship.

Return for Risk

XLVI vs. TMED — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

XLVI

XLVI Risk / Return Rank: 84
XLVI Sharpe Ratio Rank: 90
XLVI Sortino Ratio Rank: 92
XLVI Omega Ratio Rank: 90
XLVI Calmar Ratio Rank: 81
XLVI Martin Ratio Rank: 68

TMED

TMED Risk / Return Rank: 89
TMED Sharpe Ratio Rank: 90
TMED Sortino Ratio Rank: 91
TMED Omega Ratio Rank: 87
TMED Calmar Ratio Rank: 89
TMED Martin Ratio Rank: 87

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

XLVI vs. TMED - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for State Street Health Care Select Sector SPDR Premium Income ETF (XLVI) and T. Rowe Price Health Care ETF (TMED). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	XLVI	TMED	Difference
Sharpe ratio: Return per unit of total volatility	2.25	2.30	-0.05
Sortino ratio: Return per unit of downside risk	3.37	3.32	+0.05
Omega ratio: Gain probability vs. loss probability	1.42	1.39	+0.03
Calmar ratio: Return relative to maximum drawdown	2.96	3.78	-0.81
Martin ratio: Return relative to average drawdown	8.37	12.89	-4.52

XLVI vs. TMED - Sharpe Ratio Comparison

The current XLVI Sharpe Ratio is 2.25, which is comparable to the TMED Sharpe Ratio of 2.30. The chart below compares the historical Sharpe Ratios of XLVI and TMED, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

XLVI vs. TMED - Drawdown Comparison

The maximum XLVI drawdown since its inception was -8.14%, smaller than the maximum TMED drawdown of -11.11%. Use the drawdown chart below to compare losses from any high point for XLVI and TMED.

Drawdown Indicators

	XLVI	TMED	Difference
Max Drawdown Largest peak-to-trough decline	-8.14%	-11.11%	+2.97%
Max Drawdown (1Y) Largest decline over 1 year	-8.14%	-11.11%	+2.97%
Current Drawdown Current decline from peak	-1.46%	-4.25%	+2.79%
Average Drawdown Average peak-to-trough decline	-1.78%	-2.42%	+0.64%
Ulcer Index Depth and duration of drawdowns from previous peaks	2.87%	3.25%	-0.38%

Volatility

XLVI vs. TMED - Volatility Comparison

The current volatility for State Street Health Care Select Sector SPDR Premium Income ETF (XLVI) is 3.38%, while T. Rowe Price Health Care ETF (TMED) has a volatility of 5.29%. This indicates that XLVI experiences smaller price fluctuations and is considered to be less risky than TMED based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	XLVI	TMED	Difference
Volatility (1M) Calculated over the trailing 1-month period	3.38%	5.29%	-1.91%
Volatility (6M) Calculated over the trailing 6-month period	8.73%	14.06%	-5.33%
Volatility (1Y) Calculated over the trailing 1-year period	11.07%	18.41%	-7.34%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	11.05%	18.15%	-7.10%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	11.05%	18.15%	-7.10%

XLVI vs. TMED - Expense Ratio Comparison

XLVI has a 0.35% expense ratio, which is lower than TMED's 0.44% expense ratio.

Dividends

XLVI vs. TMED - Dividend Comparison

XLVI's dividend yield for the trailing twelve months is around 11.80%, more than TMED's 0.48% yield.

Position	TTM	2025
TMED T. Rowe Price Health Care ETF	0.48%	0.54%
XLVI State Street Health Care Select Sector SPDR Premium Income ETF	11.80%	5.73%

Frequently Asked Questions

Can I hold both XLVI and TMED in my portfolio?

XLVI and TMED have a correlation of 0.84, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, XLVI or TMED?

TMED has higher volatility (5.29%) compared to XLVI (3.38%). In terms of maximum drawdown, XLVI dropped -8.14% vs TMED's -11.11%.

Which ETF is better, XLVI or TMED?

On 1-year performance, TMED leads with 41.29% vs 23.20% for XLVI. On fees, XLVI is cheaper at 0.35% per year. On volatility, XLVI has been the lower-risk option at 3.38%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, XLVI or TMED?

Over the 1-year period, TMED has performed better with a 41.29% return vs 23.20%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, XLVI or TMED?

XLVI is cheaper with a 0.35% expense ratio, compared with 0.44% for TMED.

Which ETF pays a higher dividend yield, XLVI or TMED?

XLVI has the higher dividend yield at 11.80%, compared with 0.48% for TMED.

What is the main difference between XLVI and TMED?

XLVI is categorized as Derivative Income, while TMED is Health & Biotech Equities. They also come from different issuers: State Street and T. Rowe Price. Their fees differ too: 0.35% for XLVI and 0.44% for TMED.

Which has better risk-adjusted returns?

TMED currently has the higher Sharpe Ratio (2.30 vs 2.25), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.