BBP vs. WDNA

Last updated Aug 2, 2026

BBP (Virtus LifeSci Biotech Products ETF) and WDNA (WisdomTree BioRevolution Fund) are both Health & Biotech Equities funds - BBP tracks the LifeSci Biotechnology Products Index while WDNA tracks the WisdomTree BioRevolution Index. Both are passively managed. Over the past 5 years, BBP returned 13.17%/yr vs -4.37%/yr for WDNA. Their correlation of 0.85 means they have usually moved in the same direction. BBP charges 0.79%/yr vs 0.45%/yr for WDNA.

Performance

BBP vs. WDNA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Virtus LifeSci Biotech Products ETF (BBP) and WisdomTree BioRevolution Fund (WDNA). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, BBP achieves a 17.46% return, which is significantly higher than WDNA's 15.26% return.

BBP

• 1D: -2.71%
• 1M: -5.26%
• 6M: 15.00%
• YTD: 17.46%
• 1Y: 51.33%
• 3Y*: 19.80%
• 5Y*: 13.17%
• 10Y*: 11.65%
• ALL TIME*: 12.15%

WDNA

• 1D: -2.29%
• 1M: -7.98%
• 6M: 8.18%
• YTD: 15.26%
• 1Y: 47.46%
• 3Y*: 4.46%
• 5Y*: -4.37%
• 10Y*: —
• ALL TIME*: -3.49%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
BBP Virtus LifeSci Biotech Products ETF	$1.01M	$1.06M	$1.01M
WDNA WisdomTree BioRevolution Fund	$25.97K	$30.05K	$24.07K

BBP vs. WDNA - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
BBP Virtus LifeSci Biotech Products ETF	17.46%	33.15%	3.32%	17.88%	0.85%	-4.79%
WDNA WisdomTree BioRevolution Fund	15.26%	22.68%	-14.18%	-2.07%	-26.29%	-4.92%

Correlation

The correlation between BBP and WDNA is 0.82, meaning they have usually moved in the same direction, including during past declines.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.82
Correlation (3Y) Balances recent behavior with more history.	0.84
Correlation (5Y) Shows whether the relationship held over a longer period.	0.85
Correlation (All Time) Calculated using the full available price history since Jun 3, 2021	0.85

The correlation between BBP and WDNA has been stable across timeframes, ranging from 0.82 to 0.85 - a consistent structural relationship.

BBP vs. WDNA - Sectors Allocation Comparison

Sectors	BBP	WDNA
Healthcare	100.0%	90.0%
Basic Materials	-	6.3%
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	3.7%
Energy	-	1.1%
Financial Services	-	-
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

BBP vs. WDNA — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

BBP

BBP Risk / Return Rank: 90
BBP Sharpe Ratio Rank: 89
BBP Sortino Ratio Rank: 88
BBP Omega Ratio Rank: 83
BBP Calmar Ratio Rank: 95
BBP Martin Ratio Rank: 92

WDNA

WDNA Risk / Return Rank: 80
WDNA Sharpe Ratio Rank: 80
WDNA Sortino Ratio Rank: 80
WDNA Omega Ratio Rank: 72
WDNA Calmar Ratio Rank: 91
WDNA Martin Ratio Rank: 74

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

BBP vs. WDNA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Virtus LifeSci Biotech Products ETF (BBP) and WisdomTree BioRevolution Fund (WDNA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	BBP	WDNA	Difference
Sharpe ratio: Return per unit of total volatility	2.20	1.84	+0.35
Sortino ratio: Return per unit of downside risk	3.02	2.61	+0.41
Omega ratio: Gain probability vs. loss probability	1.36	1.30	+0.06
Calmar ratio: Return relative to maximum drawdown	5.61	4.00	+1.61
Martin ratio: Return relative to average drawdown	15.91	9.29	+6.62

BBP vs. WDNA - Sharpe Ratio Comparison

The current BBP Sharpe Ratio is 2.20, which is comparable to the WDNA Sharpe Ratio of 1.84. The chart below compares the historical Sharpe Ratios of BBP and WDNA, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

BBP vs. WDNA - Drawdown Comparison

The maximum BBP drawdown since its inception was -44.32%, smaller than the maximum WDNA drawdown of -58.87%. Use the drawdown chart below to compare losses from any high point for BBP and WDNA.

Drawdown Indicators

	BBP	WDNA	Difference
Max Drawdown Largest peak-to-trough decline	-44.32%	-58.87%	+14.55%
Max Drawdown (1Y) Largest decline over 1 year	-9.41%	-11.70%	+2.29%
Max Drawdown (3Y) Largest decline over 3 years	-26.09%	-36.65%	+10.56%
Max Drawdown (5Y) Largest decline over 5 years	-37.77%	-58.87%	+21.10%
Max Drawdown (10Y) Largest decline over 10 years	-44.32%	—	—
Current Drawdown Current decline from peak	-9.41%	-25.81%	+16.40%
Average Drawdown Average peak-to-trough decline	-11.90%	-35.30%	+23.40%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.31%	5.03%	-1.72%

Volatility

BBP vs. WDNA - Volatility Comparison

Virtus LifeSci Biotech Products ETF (BBP) has a higher volatility of 8.02% compared to WisdomTree BioRevolution Fund (WDNA) at 7.04%. This indicates that BBP's price experiences larger fluctuations and is considered to be riskier than WDNA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	BBP	WDNA	Difference
Volatility (1M) Calculated over the trailing 1-month period	8.02%	7.04%	+0.98%
Volatility (6M) Calculated over the trailing 6-month period	19.16%	17.23%	+1.93%
Volatility (1Y) Calculated over the trailing 1-year period	24.07%	25.54%	-1.47%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	26.42%	25.26%	+1.16%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	27.34%	25.04%	+2.30%

BBP vs. WDNA - Expense Ratio Comparison

BBP has a 0.79% expense ratio, which is higher than WDNA's 0.45% expense ratio.

Dividends

BBP vs. WDNA - Dividend Comparison

BBP has not paid dividends to shareholders, while WDNA's dividend yield for the trailing twelve months is around 3.96%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
BBP Virtus LifeSci Biotech Products ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.18%	0.00%	1.29%
WDNA WisdomTree BioRevolution Fund	3.96%	4.57%	0.75%	0.80%	0.38%	0.10%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both BBP and WDNA in my portfolio?

BBP and WDNA have a correlation of 0.82, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, BBP or WDNA?

BBP has higher volatility (8.02%) compared to WDNA (7.04%). In terms of maximum drawdown, BBP dropped -44.32% vs WDNA's -58.87%.

Which ETF is better, BBP or WDNA?

On 5-year performance, BBP leads with 13.17% vs -4.37% for WDNA. On fees, WDNA is cheaper at 0.45% per year. On volatility, WDNA has been the lower-risk option at 7.04%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, BBP or WDNA?

Over the 5-year period, BBP has performed better with a 13.17% return vs -4.37%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, BBP or WDNA?

WDNA is cheaper with a 0.45% expense ratio, compared with 0.79% for BBP.

Which ETF pays a higher dividend yield, BBP or WDNA?

WDNA has the higher dividend yield at 3.96%, compared with 0.00% for BBP.

What is the main difference between BBP and WDNA?

BBP tracks LifeSci Biotechnology Products Index, while WDNA tracks WisdomTree BioRevolution Index. They also come from different issuers: Virtus and WisdomTree. Their fees differ too: 0.79% for BBP and 0.45% for WDNA.

Which has better risk-adjusted returns?

BBP currently has the higher Sharpe Ratio (2.19 vs 1.84), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.