AMAT vs. VRTX
AMAT (Applied Materials, Inc.) and VRTX (Vertex Pharmaceuticals Incorporated) are both stocks. AMAT operates in Semiconductor Equipment & Materials (Technology), while VRTX operates in Biotechnology (Healthcare). Over the past 10 years, AMAT returned 38.86%/yr vs 17.15%/yr for VRTX. At a 0.26 correlation, their price movements are largely independent.
Performance
AMAT vs. VRTX - Performance Comparison
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Returns By Period
In the year-to-date period, AMAT achieves a 121.28% return, which is significantly higher than VRTX's -1.86% return. Over the past 10 years, AMAT has outperformed VRTX with an annualized return of 38.86%, while VRTX has yielded a comparatively lower 17.15% annualized return.
AMAT
- 1D
- 2.64%
- 1M
- 28.92%
- YTD
- 121.28%
- 6M
- 119.38%
- 1Y
- 234.96%
- 3Y*
- 60.05%
- 5Y*
- 34.02%
- 10Y*
- 38.86%
VRTX
- 1D
- -0.03%
- 1M
- -1.22%
- YTD
- -1.86%
- 6M
- -1.57%
- 1Y
- -2.31%
- 3Y*
- 9.16%
- 5Y*
- 18.18%
- 10Y*
- 17.15%
AMAT vs. VRTX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
AMAT Applied Materials, Inc. | 121.28% | 59.60% | 1.13% | 67.97% | -37.54% | 83.64% | 43.29% | 89.86% | -34.92% | 59.86% |
VRTX Vertex Pharmaceuticals Incorporated | -1.86% | 12.58% | -1.03% | 40.90% | 31.50% | -7.08% | 7.94% | 32.13% | 10.58% | 103.42% |
Correlation
The correlation between AMAT and VRTX is 0.10, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.10 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.15 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.19 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.26 |
Correlation (All Time) Calculated using the full available price history since Jul 24, 1991 | 0.26 |
The correlation between AMAT and VRTX shifts across timeframes, from 0.10 (1 year) to 0.26 (10 years), reflecting how their relationship changes across market environments.
Fundamentals
AMAT:
$453.23B
VRTX:
$114.03B
AMAT:
$10.61
VRTX:
$16.87
AMAT:
53.45
VRTX:
26.38
AMAT:
6.80
VRTX:
2.19
AMAT:
15.67
VRTX:
9.34
AMAT:
18.96
VRTX:
4.31
AMAT:
$29.02B
VRTX:
$12.26B
AMAT:
$14.21B
VRTX:
$10.57B
AMAT:
$9.92B
VRTX:
$5.19B
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Return for Risk
AMAT vs. VRTX — Risk / Return Rank
AMAT
VRTX
AMAT vs. VRTX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Applied Materials, Inc. (AMAT) and Vertex Pharmaceuticals Incorporated (VRTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| AMAT | VRTX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +4.75 | ||
| Sortino ratioReturn per unit of downside risk | +4.02 | ||
| Omega ratioGain probability vs. loss probability | 1.59 | 1.02 | +0.58 |
| Calmar ratioReturn relative to maximum drawdown | 10.67 | -0.14 | +10.81 |
| Martin ratioReturn relative to average drawdown | 30.41 | -0.29 | +30.70 |
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Drawdowns
AMAT vs. VRTX - Drawdown Comparison
The maximum AMAT drawdown since its inception was -85.22%, smaller than the maximum VRTX drawdown of -91.77%. Use the drawdown chart below to compare losses from any high point for AMAT and VRTX.
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Drawdown Indicators
| AMAT | VRTX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -85.22% | -91.77% | +6.55% |
Max Drawdown (1Y)Largest decline over 1 year | -21.37% | -23.56% | +2.19% |
Max Drawdown (3Y)Largest decline over 3 years | -49.88% | -29.07% | -20.81% |
Max Drawdown (5Y)Largest decline over 5 years | -55.14% | -29.07% | -26.07% |
Max Drawdown (10Y)Largest decline over 10 years | -55.14% | -41.60% | -13.54% |
Current DrawdownCurrent decline from peak | 0.00% | -13.90% | +13.90% |
Average DrawdownAverage peak-to-trough decline | -38.78% | -37.73% | -1.05% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 7.49% | 11.30% | -3.81% |
Volatility
AMAT vs. VRTX - Volatility Comparison
Applied Materials, Inc. (AMAT) has a higher volatility of 20.52% compared to Vertex Pharmaceuticals Incorporated (VRTX) at 7.47%. This indicates that AMAT's price experiences larger fluctuations and is considered to be riskier than VRTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| AMAT | VRTX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 20.52% | 7.47% | +13.05% |
Volatility (6M)Calculated over the trailing 6-month period | 38.83% | 20.71% | +18.12% |
Volatility (1Y)Calculated over the trailing 1-year period | 49.03% | 34.13% | +14.90% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 44.20% | 28.53% | +15.67% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 42.94% | 32.82% | +10.12% |
Dividends
AMAT vs. VRTX - Dividend Comparison
AMAT's dividend yield for the trailing twelve months is around 0.34%, while VRTX has not paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
AMAT Applied Materials, Inc. | 0.34% | 0.69% | 0.93% | 0.75% | 1.05% | 0.60% | 1.01% | 1.36% | 2.14% | 0.78% | 1.24% | 2.14% |
VRTX Vertex Pharmaceuticals Incorporated | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Financials
AMAT vs. VRTX - Financials Comparison
This section allows you to compare key financial metrics between Applied Materials, Inc. and Vertex Pharmaceuticals Incorporated. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
AMAT vs. VRTX - Profitability Comparison
AMAT - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Applied Materials, Inc. reported a gross profit of 3.95B and revenue of 7.91B. Therefore, the gross margin over that period was 49.9%.
VRTX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported a gross profit of 2.59B and revenue of 2.99B. Therefore, the gross margin over that period was 86.9%.
AMAT - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Applied Materials, Inc. reported an operating income of 2.52B and revenue of 7.91B, resulting in an operating margin of 31.9%.
VRTX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported an operating income of 1.14B and revenue of 2.99B, resulting in an operating margin of 38.1%.
AMAT - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Applied Materials, Inc. reported a net income of 2.81B and revenue of 7.91B, resulting in a net margin of 35.5%.
VRTX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported a net income of 1.03B and revenue of 2.99B, resulting in a net margin of 34.5%.
Frequently Asked Questions
AMAT and VRTX have a correlation of 0.10, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
AMAT has higher volatility (20.52%) compared to VRTX (7.47%). In terms of maximum drawdown, AMAT dropped -85.22% vs VRTX's -91.77%.
AMAT currently has the higher Sharpe Ratio (4.65 vs -0.10), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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