Invesco Dynamic Biotechnology & Genome ETF (PBE) Alternatives
Invesco Dynamic Biotechnology & Genome ETF (PBE) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with PBE. Use the tables to find lower-cost options, better risk-adjusted returns, or funds that fit a different role in your portfolio.
Cheapest Alternatives to PBE
PBE charges 0.59% annually. Among ETFs in the Health & Biotech Equities category, these options have the lowest expense ratios among PBE alternatives.
| Symbol | Name | Expense Ratio | Inception | |
|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | Oct 21, 2013 | PBE vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | Dec 16, 1998 | PBE vs XLV | |
| Vanguard Health Care ETF | 0.10% | Jan 26, 2004 | PBE vs VHT | |
| Invesco S&P SmallCap Health Care ETF | 0.29% | Apr 7, 2010 | PBE vs PSCH | |
| SPDR S&P Pharmaceuticals ETF | 0.35% | Jun 19, 2006 | PBE vs XPH |
Best Risk-Adjusted Alternatives to PBE
Among ETFs in the Health & Biotech Equities category, these options rank highest on PortfoliosLab's risk-adjusted score, which accounts for volatility, drawdown, and return consistency over a 1-year period.
| Symbol | Name | Risk / Return Rank | Inception | |
|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 97 | Dec 16, 2014 | PBE vs BBC | |
| ALPS Medical Breakthroughs ETF | 95 | Dec 31, 2014 | PBE vs SBIO | |
| SPDR S&P Biotech ETF | 92 | Feb 6, 2006 | PBE vs XBI | |
| Tema Oncology ETF | 90 | Aug 14, 2023 | PBE vs CANC | |
| F/m Emerald Life Sciences Innovation ETF | 86 | Oct 30, 2024 | PBE vs LFSC |
Top Performing PBE Alternatives (YTD)
PBE alternatives from the Health & Biotech Equities category, sorted by year-to-date return.
| Symbol | Name | YTD Return | Inception | |
|---|---|---|---|---|
| iShares Genomics Immunology and Healthcare ETF Gen... | 10.92% | Jun 11, 2019 | PBE vs IDNA | |
| Virtus LifeSci Biotech Clinical Trials ETF | 7.95% | Dec 16, 2014 | PBE vs BBC | |
| Tema Oncology ETF | 5.69% | Aug 14, 2023 | PBE vs CANC | |
| SPDR S&P Biotech ETF | 4.76% | Feb 6, 2006 | PBE vs XBI | |
| First Trust Nasdaq Pharmaceuticals ETF | 4.48% | Sep 20, 2016 | PBE vs FTXH |
Lowest Volatility Alternatives to PBE
PBE alternatives from the Health & Biotech Equities category, sorted by annualized volatility over the past year.
| Symbol | Name | Volatility 1Y | Inception | |
|---|---|---|---|---|
| Principal Healthcare Innovators Index ETF | 0.00% | Aug 19, 2016 | PBE vs BTEC | |
| Loncar Cancer Immunotherapy ETF | 0.00% | Oct 13, 2015 | PBE vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | Jun 17, 2020 | PBE vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.60% | Jun 29, 2007 | PBE vs SPAQ | |
| Global X Aging Population ETF | 15.94% | May 9, 2016 | PBE vs AGNG |
Lowest Drawdown Alternatives to PBE
PBE alternatives from the Health & Biotech Equities category, sorted by maximum drawdown over the past year.
| Symbol | Name | Max Drawdown 1Y | Inception | |
|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | Jun 17, 2020 | PBE vs GERM | |
| Horizon Kinetics SPAC Active ETF | -5.30% | Jun 29, 2007 | PBE vs SPAQ | |
| Jpmorgan Healthcare Leaders ETF | -9.68% | Nov 1, 2023 | PBE vs JDOC | |
| VanEck Vectors Pharmaceutical ETF | -10.02% | Dec 20, 2011 | PBE vs PPH | |
| Global X Aging Population ETF | -10.16% | May 9, 2016 | PBE vs AGNG |
Other ETFs from Invesco
Most popular Invesco ETFs on PortfoliosLab, across asset classes.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | Inception | |
|---|---|---|---|---|---|---|
| Invesco QQQ ETF | Large Cap Growth Equities | 69 | -5.93% | Mar 10, 1999 | PBE vs QQQ | |
| Invesco S&P 500 Momentum ETF | S&P 500 | 66 | -5.78% | Oct 9, 2015 | PBE vs SPMO | |
| Invesco NASDAQ 100 ETF | Large Cap Growth Equities | 70 | -5.92% | Oct 13, 2020 | PBE vs QQQM | |
| Invesco S&P 500 Equal Weight ETF | S&P 500 | 47 | 0.62% | Apr 24, 2003 | PBE vs RSP | |
| Invesco S&P 500 Top 50 ETF | S&P 500 | 63 | -7.82% | May 4, 2005 | PBE vs XLG | |
| Invesco S&P 500 Quality ETF | S&P 500, Large Cap Value Equities | 58 | 0.57% | Dec 6, 2005 | PBE vs SPHQ | |
| Invesco S&P 500® High Dividend Low Volatility ETF | S&P 500, Dividend | 20 | 4.64% | Oct 18, 2012 | PBE vs SPHD | |
| Invesco PHLX Semiconductor ETF | Semiconductors, Technology Equities | 93 | 7.17% | Jun 11, 2021 | PBE vs SOXQ | |
| Invesco Aerospace & Defense ETF | Industrials Equities, Aerospace & Defense | 92 | 5.82% | Oct 26, 2005 | PBE vs PPA | |
| Invesco S&P MidCap Momentum ETF | Mid Cap Growth Equities | 80 | 4.93% | Mar 3, 2005 | PBE vs XMMO |
Often Compared With PBE
What investors most often compare with PBE, based on PortfoliosLab usage data.
Compare PBE with Any Fund or Stock
Compare PBE with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.