Jpmorgan Healthcare Leaders ETF (JDOC) belongs to the Health & Biotech Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with JDOC. Use the tables to find lower-cost options, better risk-adjusted returns, or a closer substitute for your current allocation.
Cheapest Alternatives to JDOC
JDOC charges 0.65% annually. There are 43 ETFs in the Health & Biotech Equities category with lower expense ratios, going as low as 0.08%.
| Symbol | Name | Expense Ratio | AUM | Inception | |
|---|---|---|---|---|---|
| Fidelity MSCI Health Care Index ETF | 0.08% | 3.22B | Oct 2013 | JDOC vs FHLC | |
| State Street Health Care Select Sector SPDR ETF | 0.08% | 42.10B | Dec 1998 | JDOC vs XLV | |
| Vanguard Health Care ETF | 0.09% | 20.40B | Jan 2004 | JDOC vs VHT | |
| VanEck Healthcare TruSector ETF | 0.10% | 850.50K | Apr 2026 | JDOC vs TRUH | |
| Portfolio Building Block World Pharma and Biotech ... | 0.13% | 933.15M | Nov 2025 | JDOC vs PBPH |
Best Risk-Adjusted Alternatives to JDOC
JDOC has a PortfoliosLab risk / return rank of 63. There are 37 ETFs in the Health & Biotech Equities category with higher risk-adjusted ranks, going as high as 96.
| Symbol | Name | Risk / Return Rank | AUM | Inception | |
|---|---|---|---|---|---|
| Virtus LifeSci Biotech Clinical Trials ETF | 96 | 47.80M | Dec 2014 | JDOC vs BBC | |
| iShares U.S. Pharmaceuticals ETF | 95 | 1.65B | May 2006 | JDOC vs IHE | |
| First Trust Nasdaq Pharmaceuticals ETF | 95 | 911.09M | Sep 2016 | JDOC vs FTXH | |
| ALPS Medical Breakthroughs ETF | 95 | 201.57M | Dec 2014 | JDOC vs SBIO | |
| Invesco Dynamic Pharmaceuticals ETF | 94 | 472.10M | Jun 2005 | JDOC vs PJP |
Top Performing JDOC Alternatives (YTD)
JDOC is at 4.29% YTD. There are 45 ETFs in the Health & Biotech Equities category with higher YTD returns, going as high as 36.76%.
| Symbol | Name | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|
| ARK Genomic Revolution Multi-Sector ETF | 36.76% | 1.73B | Oct 2014 | JDOC vs ARKG | |
| AdvisorShares Psychedelics ETF | 36.69% | 48.53M | Sep 2021 | JDOC vs PSIL | |
| Roundhill UNH WeeklyPay ETF | 28.89% | 7.27M | Dec 2025 | JDOC vs UNHW | |
| Virtus LifeSci Biotech Clinical Trials ETF | 27.03% | 47.80M | Dec 2014 | JDOC vs BBC | |
| SPDR S&P Health Care Services ETF | 25.67% | 206.72M | Sep 2011 | JDOC vs XHS |
Lowest Volatility Alternatives to JDOC
JDOC has 14.82% 1-year volatility. There are 6 ETFs in the Health & Biotech Equities category with lower 1-year volatility, going as low as 0.00%.
| Symbol | Name | Volatility 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Loncar Cancer Immunotherapy ETF | 0.00% | 12.73M | Oct 2015 | JDOC vs CNCR | |
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | JDOC vs GERM | |
| Horizon Kinetics SPAC Active ETF | 8.66% | 10.09M | Jun 2007 | JDOC vs SPAQ | |
| State Street Health Care Select Sector SPDR Premiu... | 10.75% | 21.55M | Jul 2025 | JDOC vs XLVI | |
| Milliman Healthcare Inflation Plus ETF | 10.92% | 982.35K | Apr 2026 | JDOC vs MHIP |
Lowest Drawdown Alternatives to JDOC
JDOC has a 1-year max drawdown of -9.68%. There are 11 ETFs in the Health & Biotech Equities category with shallower 1-year drawdowns, going as shallow as 0.00%.
| Symbol | Name | Max Drawdown 1Y | AUM | Inception | |
|---|---|---|---|---|---|
| Amplify Treatments, Testing and Advancements ETF | 0.00% | 9.68M | Jun 2020 | JDOC vs GERM | |
| Horizon Kinetics SPAC Active ETF | -4.20% | 10.09M | Jun 2007 | JDOC vs SPAQ | |
| First Trust Nasdaq Pharmaceuticals ETF | -7.47% | 911.09M | Sep 2016 | JDOC vs FTXH | |
| State Street Health Care Select Sector SPDR Premiu... | -8.14% | 21.55M | Jul 2025 | JDOC vs XLVI | |
| Invesco Nasdaq Biotechnology ETF | -8.34% | 75.06M | Jun 2021 | JDOC vs IBBQ |
Other ETFs from JPMorgan
The 10 most viewed JPMorgan ETFs shown here include JEPQ, JEPI, JPST and span 12 categories. AUM among these funds goes as high as $46B.
| Symbol | Name | Category | Risk / Return Rank | YTD Return | AUM | Inception | |
|---|---|---|---|---|---|---|---|
| JPMorgan Nasdaq Equity Premium Income ETF | Nasdaq-100, Derivative Income | 66 | 7.51% | 39.88B | May 2022 | JDOC vs JEPQ | |
| JPMorgan Equity Premium Income ETF | Dividend, Derivative Income | 56 | 5.04% | 45.80B | May 2020 | JDOC vs JEPI | |
| JPMorgan Ultra-Short Income ETF | Ultrashort Bond | 99 | 2.01% | 40.48B | May 2017 | JDOC vs JPST | |
| JPMorgan Income ETF | Multisector Bonds | 95 | 1.92% | 10.22B | Oct 2021 | JDOC vs JPIE | |
| JPMorgan U.S. Quality Factor ETF | Quality Factor, Large Cap Blend Equities | 83 | 15.84% | 8.22B | Nov 2017 | JDOC vs JQUA | |
| JPMorgan Hedged Equity Laddered Overlay ETF | Options Trading | 65 | 4.18% | 4.62B | Sep 2023 | JDOC vs HELO | |
| JPMorgan U.S. Tech Leaders ETF | Technology Equities, Actively Managed | 26 | 7.76% | 4.11B | Oct 2023 | JDOC vs JTEK | |
| JPMorgan U.S. Momentum Factor ETF | Momentum, Large Cap Blend Equities | 80 | 20.54% | 2.50B | Nov 2017 | JDOC vs JMOM | |
| JPMorgan Limited Duration Bond ETF | Short-Term Bond | 93 | 1.59% | 3.95B | Feb 1993 | JDOC vs JPLD | |
| JPMorgan BetaBuilders U.S. Equity ETF | Large Cap Blend Equities | 74 | 11.30% | 8.89B | Mar 2019 | JDOC vs BBUS |
Often Compared With JDOC
Investors most often compare JDOC with IWVL.L, IYH, IXJ. These 20 comparison targets span 4 categories, based on PortfoliosLab usage data.
Compare JDOC with Any Fund or Stock
Compare JDOC with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.
Pair JDOC with funds that move differently
Jpmorgan Healthcare Leaders ETF alternatives help with substitution. Diversifiers are the next step when you want funds with lower historical correlation to JDOC.
Explore JDOC Diversifiers