JDOC vs. PBE

Last updated Apr 1, 2026

Compare and contrast key facts about Jpmorgan Healthcare Leaders ETF (JDOC) and Invesco Dynamic Biotechnology & Genome ETF (PBE).

JDOC and PBE are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. JDOC is an actively managed fund by JPMorgan. It was launched on Nov 1, 2023. PBE is a passively managed fund by Invesco that tracks the performance of the Dynamic Biotech & Genome Intellidex Index (AMEX). It was launched on Jun 23, 2005.

Performance

JDOC vs. PBE - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Jpmorgan Healthcare Leaders ETF (JDOC) and Invesco Dynamic Biotechnology & Genome ETF (PBE). The values are adjusted to include any dividend payments, if applicable.

JDOC vs. PBE - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
JDOC Jpmorgan Healthcare Leaders ETF	-3.96%	15.36%	-1.04%	10.71%
PBE Invesco Dynamic Biotechnology & Genome ETF	-3.51%	24.84%	1.10%	20.84%

Returns By Period

In the year-to-date period, JDOC achieves a -3.96% return, which is significantly lower than PBE's -3.51% return.

JDOC

• 1D: 2.32%
• 1M: -6.11%
• YTD: -3.96%
• 6M: 6.94%
• 1Y: 5.14%
• 3Y*: —
• 5Y*: —
• 10Y*: —

PBE

• 1D: 3.03%
• 1M: -3.31%
• YTD: -3.51%
• 6M: 14.03%
• 1Y: 26.26%
• 3Y*: 8.51%
• 5Y*: 1.51%
• 10Y*: 7.52%

*Multi-year figures are annualized to reflect compound growth (CAGR)

JDOC vs. PBE - Expense Ratio Comparison

JDOC has a 0.65% expense ratio, which is higher than PBE's 0.59% expense ratio.

JDOC

Jpmorgan Healthcare Leaders ETF

PBE

Invesco Dynamic Biotechnology & Genome ETF

Return for Risk

JDOC vs. PBE — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

JDOC

JDOC Risk / Return Rank: 21
JDOC Sharpe Ratio Rank: 20
JDOC Sortino Ratio Rank: 20
JDOC Omega Ratio Rank: 19
JDOC Calmar Ratio Rank: 24
JDOC Martin Ratio Rank: 20

PBE

PBE Risk / Return Rank: 68
PBE Sharpe Ratio Rank: 68
PBE Sortino Ratio Rank: 70
PBE Omega Ratio Rank: 60
PBE Calmar Ratio Rank: 79
PBE Martin Ratio Rank: 63

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

JDOC vs. PBE - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Jpmorgan Healthcare Leaders ETF (JDOC) and Invesco Dynamic Biotechnology & Genome ETF (PBE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	JDOC	PBE	Difference
Sharpe ratio Return per unit of total volatility	0.30	1.16	-0.86
Sortino ratio Return per unit of downside risk	0.54	1.73	-1.20
Omega ratio Gain probability vs. loss probability	1.07	1.22	-0.15
Calmar ratio Return relative to maximum drawdown	0.54	2.12	-1.58
Martin ratio Return relative to average drawdown	1.24	6.21	-4.97
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

JDOC vs. PBE - Sharpe Ratio Comparison

The current JDOC Sharpe Ratio is 0.30, which is lower than the PBE Sharpe Ratio of 1.16. The chart below compares the historical Sharpe Ratios of JDOC and PBE, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	JDOC	PBE	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.30	1.16	-0.86
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.07	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.30	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.59	0.32	+0.27

Correlation

The correlation between JDOC and PBE is 0.73, which is considered to be high. That indicates a strong positive relationship between their price movements. Having highly-correlated positions in a portfolio may signal a lack of diversification, potentially leading to increased risk during market downturns.

Dividends

JDOC vs. PBE - Dividend Comparison

JDOC's dividend yield for the trailing twelve months is around 0.92%, less than PBE's 1.09% yield.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
JDOC Jpmorgan Healthcare Leaders ETF	0.92%	0.89%	5.57%	0.15%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
PBE Invesco Dynamic Biotechnology & Genome ETF	1.09%	1.00%	0.05%	0.02%	0.00%	0.00%	0.04%	0.00%	0.00%	0.57%	0.38%	1.12%

Drawdowns

JDOC vs. PBE - Drawdown Comparison

The maximum JDOC drawdown since its inception was -20.87%, smaller than the maximum PBE drawdown of -45.69%. Use the drawdown chart below to compare losses from any high point for JDOC and PBE.

Drawdown Indicators

	JDOC	PBE	Difference
Max Drawdown Largest peak-to-trough decline	-20.87%	-45.69%	+24.82%
Max Drawdown (1Y) Largest decline over 1 year	-9.68%	-11.73%	+2.05%
Max Drawdown (5Y) Largest decline over 5 years	—	-34.71%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-37.84%	—
Current Drawdown Current decline from peak	-6.96%	-7.54%	+0.58%
Average Drawdown Average peak-to-trough decline	-7.01%	-16.33%	+9.32%
Ulcer Index Depth and duration of drawdowns from previous peaks	4.61%	4.01%	+0.60%

Volatility

JDOC vs. PBE - Volatility Comparison

The current volatility for Jpmorgan Healthcare Leaders ETF (JDOC) is 5.67%, while Invesco Dynamic Biotechnology & Genome ETF (PBE) has a volatility of 7.57%. This indicates that JDOC experiences smaller price fluctuations and is considered to be less risky than PBE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	JDOC	PBE	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.67%	7.57%	-1.90%
Volatility (6M) Calculated over the trailing 6-month period	10.15%	13.75%	-3.60%
Volatility (1Y) Calculated over the trailing 1-year period	17.04%	22.72%	-5.68%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	14.33%	22.70%	-8.37%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	14.33%	25.15%	-10.82%