VRTX vs. ROST
VRTX (Vertex Pharmaceuticals Incorporated) and ROST (Ross Stores, Inc.) are both stocks. VRTX operates in Biotechnology (Healthcare), while ROST operates in Apparel Retail (Consumer Cyclical). Over the past 10 years, VRTX returned 17.15%/yr vs 17.29%/yr for ROST. At a 0.20 correlation, their price movements are largely independent.
Performance
VRTX vs. ROST - Performance Comparison
Loading charts...
Returns By Period
In the year-to-date period, VRTX achieves a -1.86% return, which is significantly lower than ROST's 33.85% return. Both investments have delivered pretty close results over the past 10 years, with VRTX having a 17.15% annualized return and ROST not far ahead at 17.29%.
VRTX
- 1D
- -0.03%
- 1M
- -1.22%
- YTD
- -1.86%
- 6M
- -1.57%
- 1Y
- -2.31%
- 3Y*
- 9.16%
- 5Y*
- 18.18%
- 10Y*
- 17.15%
ROST
- 1D
- 0.43%
- 1M
- 12.82%
- YTD
- 33.85%
- 6M
- 32.41%
- 1Y
- 83.78%
- 3Y*
- 32.49%
- 5Y*
- 16.14%
- 10Y*
- 17.29%
VRTX vs. ROST - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
VRTX Vertex Pharmaceuticals Incorporated | -1.86% | 12.58% | -1.03% | 40.90% | 31.50% | -7.08% | 7.94% | 32.13% | 10.58% | 103.42% |
ROST Ross Stores, Inc. | 33.85% | 20.41% | 10.39% | 20.64% | 2.94% | -6.03% | 5.81% | 41.72% | 4.78% | 23.53% |
Correlation
The correlation between VRTX and ROST is 0.24, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.24 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.24 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.26 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.22 |
Correlation (All Time) Calculated using the full available price history since Jul 24, 1991 | 0.20 |
Fundamentals
VRTX:
$114.03B
ROST:
$77.14B
VRTX:
$16.87
ROST:
$7.15
VRTX:
26.38
ROST:
33.57
VRTX:
2.19
ROST:
3.80
VRTX:
9.34
ROST:
3.27
VRTX:
4.31
ROST:
11.69
VRTX:
$12.26B
ROST:
$23.78B
VRTX:
$10.57B
ROST:
$4.95B
VRTX:
$5.19B
ROST:
$3.62B
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
Return for Risk
VRTX vs. ROST — Risk / Return Rank
VRTX
ROST
VRTX vs. ROST - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Vertex Pharmaceuticals Incorporated (VRTX) and Ross Stores, Inc. (ROST). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| VRTX | ROST | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -3.44 | ||
| Sortino ratioReturn per unit of downside risk | -4.84 | ||
| Omega ratioGain probability vs. loss probability | 1.02 | 1.63 | -0.62 |
| Calmar ratioReturn relative to maximum drawdown | -0.14 | 10.52 | -10.66 |
| Martin ratioReturn relative to average drawdown | -0.29 | 38.37 | -38.66 |
Loading charts...
Drawdowns
VRTX vs. ROST - Drawdown Comparison
The maximum VRTX drawdown since its inception was -91.77%, which is greater than ROST's maximum drawdown of -82.23%. Use the drawdown chart below to compare losses from any high point for VRTX and ROST.
Loading charts...
Drawdown Indicators
| VRTX | ROST | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -91.77% | -82.23% | -9.54% |
Max Drawdown (1Y)Largest decline over 1 year | -23.56% | -7.79% | -15.77% |
Max Drawdown (3Y)Largest decline over 3 years | -29.07% | -21.08% | -7.99% |
Max Drawdown (5Y)Largest decline over 5 years | -29.07% | -44.13% | +15.06% |
Max Drawdown (10Y)Largest decline over 10 years | -41.60% | -51.41% | +9.81% |
Current DrawdownCurrent decline from peak | -13.90% | 0.00% | -13.90% |
Average DrawdownAverage peak-to-trough decline | -37.73% | -17.93% | -19.80% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 11.30% | 2.25% | +9.05% |
Volatility
VRTX vs. ROST - Volatility Comparison
The current volatility for Vertex Pharmaceuticals Incorporated (VRTX) is 7.47%, while Ross Stores, Inc. (ROST) has a volatility of 10.90%. This indicates that VRTX experiences smaller price fluctuations and is considered to be less risky than ROST based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading charts...
Volatility by Period
| VRTX | ROST | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 7.47% | 10.90% | -3.43% |
Volatility (6M)Calculated over the trailing 6-month period | 20.71% | 18.51% | +2.20% |
Volatility (1Y)Calculated over the trailing 1-year period | 34.13% | 24.63% | +9.50% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 28.53% | 29.55% | -1.02% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 32.82% | 31.62% | +1.20% |
Dividends
VRTX vs. ROST - Dividend Comparison
VRTX has not paid dividends to shareholders, while ROST's dividend yield for the trailing twelve months is around 0.71%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
ROST Ross Stores, Inc. | 0.71% | 0.90% | 0.97% | 0.97% | 1.07% | 1.00% | 0.23% | 1.10% | 1.08% | 0.80% | 0.82% | 4.59% |
VRTX Vertex Pharmaceuticals Incorporated | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Financials
VRTX vs. ROST - Financials Comparison
This section allows you to compare key financial metrics between Vertex Pharmaceuticals Incorporated and Ross Stores, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
VRTX vs. ROST - Profitability Comparison
VRTX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported a gross profit of 2.59B and revenue of 2.99B. Therefore, the gross margin over that period was 86.9%.
ROST - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Ross Stores, Inc. reported a gross profit of 0.00 and revenue of 6.01B. Therefore, the gross margin over that period was 0.0%.
VRTX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported an operating income of 1.14B and revenue of 2.99B, resulting in an operating margin of 38.1%.
ROST - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Ross Stores, Inc. reported an operating income of 804.03M and revenue of 6.01B, resulting in an operating margin of 13.4%.
VRTX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported a net income of 1.03B and revenue of 2.99B, resulting in a net margin of 34.5%.
ROST - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Ross Stores, Inc. reported a net income of 649.96M and revenue of 6.01B, resulting in a net margin of 10.8%.
Frequently Asked Questions
VRTX and ROST have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
ROST has higher volatility (10.90%) compared to VRTX (7.47%). In terms of maximum drawdown, VRTX dropped -91.77% vs ROST's -82.23%.
ROST currently has the higher Sharpe Ratio (3.34 vs -0.10), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
Find the right allocation for VRTX and ROST
Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.
Open Portfolio Optimizer