VRTX vs. PDBC

Last updated Jun 4, 2026

VRTX (Vertex Pharmaceuticals Incorporated) is a stock, while PDBC (Invesco Optimum Yield Diversified Commodity Strategy No K-1 ETF) is Commodities fund actively managed by Invesco. Over the past 10 years, VRTX returned 16.38%/yr vs 8.79%/yr for PDBC. At a 0.09 correlation, their price movements are largely independent.

Performance

VRTX vs. PDBC - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Vertex Pharmaceuticals Incorporated (VRTX) and Invesco Optimum Yield Diversified Commodity Strategy No K-1 ETF (PDBC). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, VRTX achieves a -5.52% return, which is significantly lower than PDBC's 36.23% return. Over the past 10 years, VRTX has outperformed PDBC with an annualized return of 16.38%, while PDBC has yielded a comparatively lower 8.79% annualized return.

VRTX

• 1D: 0.76%
• 1M: -0.35%
• YTD: -5.52%
• 6M: -7.51%
• 1Y: -4.06%
• 3Y*: 8.67%
• 5Y*: 15.33%
• 10Y*: 16.38%

PDBC

• 1D: 0.39%
• 1M: -3.37%
• YTD: 36.23%
• 6M: 36.27%
• 1Y: 45.46%
• 3Y*: 14.42%
• 5Y*: 12.39%
• 10Y*: 8.79%

*Multi-year figures are annualized to reflect compound growth (CAGR)

VRTX vs. PDBC - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
VRTX Vertex Pharmaceuticals Incorporated	-5.52%	12.58%	-1.03%	40.90%	31.50%	-7.08%	7.94%	32.13%	10.58%	103.42%
PDBC Invesco Optimum Yield Diversified Commodity Strategy No K-1 ETF	36.23%	5.96%	2.09%	-6.25%	19.23%	41.72%	-7.84%	11.44%	-12.78%	5.06%

Correlation

The correlation between VRTX and PDBC is -0.09, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	-0.09
Correlation (3Y) Calculated over the trailing 3-year period	-0.02
Correlation (5Y) Calculated over the trailing 5-year period	0.02
Correlation (10Y) Calculated over the trailing 10-year period	0.09
Correlation (All Time) Calculated using the full available price history since Nov 10, 2014	0.09

The correlation between VRTX and PDBC shifts across timeframes, from -0.09 (1 year) to 0.09 (10 years), reflecting how their relationship changes across market environments.

Return for Risk

VRTX vs. PDBC — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

VRTX

VRTX Risk / Return Rank: 33
VRTX Sharpe Ratio Rank: 36
VRTX Sortino Ratio Rank: 31
VRTX Omega Ratio Rank: 31
VRTX Calmar Ratio Rank: 34
VRTX Martin Ratio Rank: 33

PDBC

PDBC Risk / Return Rank: 74
PDBC Sharpe Ratio Rank: 73
PDBC Sortino Ratio Rank: 67
PDBC Omega Ratio Rank: 70
PDBC Calmar Ratio Rank: 92
PDBC Martin Ratio Rank: 70

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

VRTX vs. PDBC - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Vertex Pharmaceuticals Incorporated (VRTX) and Invesco Optimum Yield Diversified Commodity Strategy No K-1 ETF (PDBC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	VRTX	PDBC	Difference
Sharpe ratio: Return per unit of total volatility	-0.12	2.46	-2.58
Sortino ratio: Return per unit of downside risk	0.07	3.14	-3.07
Omega ratio: Gain probability vs. loss probability	1.01	1.43	-0.42
Calmar ratio: Return relative to maximum drawdown	-0.17	6.35	-6.52
Martin ratio: Return relative to average drawdown	-0.37	13.39	-13.75
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

VRTX vs. PDBC - Sharpe Ratio Comparison

The current VRTX Sharpe Ratio is -0.12, which is lower than the PDBC Sharpe Ratio of 2.46. The chart below compares the historical Sharpe Ratios of VRTX and PDBC, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	VRTX	PDBC	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.12	2.46	-2.58
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.53	0.65	-0.12
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.50	0.50	0.00
Sharpe Ratio (All Time) Calculated using the full available price history	0.25	0.23	+0.02

Drawdowns

VRTX vs. PDBC - Drawdown Comparison

The maximum VRTX drawdown since its inception was -91.77%, which is greater than PDBC's maximum drawdown of -49.52%. Use the drawdown chart below to compare losses from any high point for VRTX and PDBC.

Drawdown Indicators

	VRTX	PDBC	Difference
Max Drawdown Largest peak-to-trough decline	-91.77%	-49.52%	-42.25%
Max Drawdown (1Y) Largest decline over 1 year	-23.56%	-7.19%	-16.37%
Max Drawdown (3Y) Largest decline over 3 years	-29.07%	-13.95%	-15.12%
Max Drawdown (5Y) Largest decline over 5 years	-29.07%	-27.63%	-1.44%
Max Drawdown (10Y) Largest decline over 10 years	-41.60%	-40.73%	-0.87%
Current Drawdown Current decline from peak	-17.11%	-4.55%	-12.56%
Average Drawdown Average peak-to-trough decline	-37.70%	-23.21%	-14.49%
Ulcer Index Depth and duration of drawdowns from previous peaks	11.14%	3.41%	+7.73%

Volatility

VRTX vs. PDBC - Volatility Comparison

Vertex Pharmaceuticals Incorporated (VRTX) has a higher volatility of 7.03% compared to Invesco Optimum Yield Diversified Commodity Strategy No K-1 ETF (PDBC) at 6.20%. This indicates that VRTX's price experiences larger fluctuations and is considered to be riskier than PDBC based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	VRTX	PDBC	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.03%	6.20%	+0.83%
Volatility (6M) Calculated over the trailing 6-month period	21.69%	15.78%	+5.91%
Volatility (1Y) Calculated over the trailing 1-year period	33.88%	18.61%	+15.27%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	28.90%	19.12%	+9.78%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	32.82%	17.78%	+15.04%

Dividends

VRTX vs. PDBC - Dividend Comparison

VRTX has not paid dividends to shareholders, while PDBC's dividend yield for the trailing twelve months is around 2.82%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016
PDBC Invesco Optimum Yield Diversified Commodity Strategy No K-1 ETF	2.82%	3.84%	4.42%	4.21%	13.05%	50.83%	0.01%	1.40%	1.00%	3.83%	6.51%
VRTX Vertex Pharmaceuticals Incorporated	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both VRTX and PDBC in my portfolio?

VRTX and PDBC have a correlation of -0.09, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, VRTX or PDBC?

VRTX has higher volatility (7.03%) compared to PDBC (6.20%). In terms of maximum drawdown, VRTX dropped -91.77% vs PDBC's -49.52%.

Which has better risk-adjusted returns?

PDBC currently has the higher Sharpe Ratio (2.46 vs -0.12), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.