NUVB vs. XERS
NUVB (Nuvation Bio Inc.) and XERS (Xeris Biopharma Holdings, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, NUVB returned -15.85%/yr vs 8.71%/yr for XERS. At a 0.25 correlation, their price movements are largely independent.
Performance
NUVB vs. XERS - Performance Comparison
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Returns By Period
In the year-to-date period, NUVB achieves a -42.30% return, which is significantly lower than XERS's -21.66% return.
NUVB
- 1D
- 9.53%
- 1M
- 7.04%
- YTD
- -42.30%
- 6M
- -37.79%
- 1Y
- 111.02%
- 3Y*
- 45.17%
- 5Y*
- -15.85%
- 10Y*
- —
XERS
- 1D
- 4.41%
- 1M
- -1.28%
- YTD
- -21.66%
- 6M
- -8.48%
- 1Y
- 38.83%
- 3Y*
- 29.38%
- 5Y*
- 8.71%
- 10Y*
- —
NUVB vs. XERS - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|---|
NUVB Nuvation Bio Inc. | -42.30% | 236.84% | 76.16% | -21.35% | -77.41% | -27.35% | 17.00% |
XERS Xeris Biopharma Holdings, Inc. | -21.66% | 131.56% | 44.26% | 76.69% | -54.61% | -40.45% | 31.55% |
Correlation
The correlation between NUVB and XERS is 0.21, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.21 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.28 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.28 |
Correlation (All Time) Calculated using the full available price history since Aug 25, 2020 | 0.25 |
Fundamentals
NUVB:
$1.95B
XERS:
$1.09B
NUVB:
-$0.42
XERS:
$0.07
NUVB:
12.69
XERS:
3.38
NUVB:
6.11
XERS:
83.96
NUVB:
$143.05M
XERS:
$314.85M
NUVB:
$131.08M
XERS:
$187.04M
NUVB:
-$139.03M
XERS:
$41.72M
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Return for Risk
NUVB vs. XERS — Risk / Return Rank
NUVB
XERS
NUVB vs. XERS - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Nuvation Bio Inc. (NUVB) and Xeris Biopharma Holdings, Inc. (XERS). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| NUVB | XERS | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.52 | ||
| Sortino ratioReturn per unit of downside risk | +0.79 | ||
| Omega ratioGain probability vs. loss probability | 1.29 | 1.18 | +0.11 |
| Calmar ratioReturn relative to maximum drawdown | 1.94 | 0.84 | +1.10 |
| Martin ratioReturn relative to average drawdown | 3.54 | 1.52 | +2.03 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| NUVB | XERS | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.22 | 0.70 | +0.52 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.21 | 0.13 | -0.34 |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.15 | -0.18 | +0.03 |
Drawdowns
NUVB vs. XERS - Drawdown Comparison
The maximum NUVB drawdown since its inception was -93.39%, roughly equal to the maximum XERS drawdown of -96.22%. Use the drawdown chart below to compare losses from any high point for NUVB and XERS.
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Drawdown Indicators
| NUVB | XERS | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -93.39% | -96.22% | +2.83% |
Max Drawdown (1Y)Largest decline over 1 year | -57.55% | -46.57% | -10.98% |
Max Drawdown (3Y)Largest decline over 3 years | -58.19% | -50.67% | -7.52% |
Max Drawdown (5Y)Largest decline over 5 years | -92.88% | -78.59% | -14.29% |
Current DrawdownCurrent decline from peak | -64.52% | -77.41% | +12.89% |
Average DrawdownAverage peak-to-trough decline | -65.50% | -79.05% | +13.55% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 31.46% | 25.69% | +5.77% |
Volatility
NUVB vs. XERS - Volatility Comparison
Nuvation Bio Inc. (NUVB) has a higher volatility of 18.34% compared to Xeris Biopharma Holdings, Inc. (XERS) at 13.38%. This indicates that NUVB's price experiences larger fluctuations and is considered to be riskier than XERS based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| NUVB | XERS | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 18.34% | 13.38% | +4.96% |
Volatility (6M)Calculated over the trailing 6-month period | 53.53% | 33.84% | +19.69% |
Volatility (1Y)Calculated over the trailing 1-year period | 91.74% | 55.78% | +35.96% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 75.58% | 68.53% | +7.05% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 73.11% | 79.18% | -6.07% |
Dividends
NUVB vs. XERS - Dividend Comparison
Neither NUVB nor XERS has paid dividends to shareholders.
Financials
NUVB vs. XERS - Financials Comparison
This section allows you to compare key financial metrics between Nuvation Bio Inc. and Xeris Biopharma Holdings, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
NUVB vs. XERS - Profitability Comparison
NUVB - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Nuvation Bio Inc. reported a gross profit of 77.61M and revenue of 83.23M. Therefore, the gross margin over that period was 93.3%.
XERS - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Xeris Biopharma Holdings, Inc. reported a gross profit of 0.00 and revenue of 83.13M. Therefore, the gross margin over that period was 0.0%.
NUVB - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Nuvation Bio Inc. reported an operating income of 3.88M and revenue of 83.23M, resulting in an operating margin of 4.7%.
XERS - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Xeris Biopharma Holdings, Inc. reported an operating income of 7.92M and revenue of 83.13M, resulting in an operating margin of 9.5%.
NUVB - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Nuvation Bio Inc. reported a net income of 5.40M and revenue of 83.23M, resulting in a net margin of 6.5%.
XERS - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Xeris Biopharma Holdings, Inc. reported a net income of 2.23M and revenue of 83.13M, resulting in a net margin of 2.7%.
Frequently Asked Questions
NUVB and XERS have a correlation of 0.21, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
NUVB has higher volatility (18.34%) compared to XERS (13.38%). In terms of maximum drawdown, NUVB dropped -93.39% vs XERS's -96.22%.
NUVB currently has the higher Sharpe Ratio (1.22 vs 0.70), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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