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NUVB vs. URGN
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

NUVB vs. URGN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Nuvation Bio Inc. (NUVB) and UroGen Pharma Ltd. (URGN). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, NUVB achieves a -47.32% return, which is significantly lower than URGN's 13.58% return.


NUVB

1D
-3.67%
1M
7.03%
YTD
-47.32%
6M
-43.61%
1Y
92.65%
3Y*
40.28%
5Y*
-17.37%
10Y*

URGN

1D
0.23%
1M
14.21%
YTD
13.58%
6M
9.24%
1Y
432.00%
3Y*
39.78%
5Y*
8.15%
10Y*
*Multi-year figures are annualized to reflect compound growth (CAGR)

NUVB vs. URGN - Yearly Performance Comparison


2026 (YTD)202520242023202220212020
NUVB
Nuvation Bio Inc.
-47.32%236.84%76.16%-21.35%-77.41%-27.35%17.00%
URGN
UroGen Pharma Ltd.
13.58%119.91%-29.00%69.11%-6.73%-47.23%-21.48%

Correlation

The correlation between NUVB and URGN is 0.28, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.28

Correlation (3Y)
Calculated over the trailing 3-year period

0.24

Correlation (5Y)
Calculated over the trailing 5-year period

0.28

Correlation (All Time)
Calculated using the full available price history since Aug 25, 2020

0.27

Fundamentals

Market Cap

NUVB:

$1.78B

URGN:

$1.33B

EPS

NUVB:

-$0.42

URGN:

-$2.73

PS Ratio

NUVB:

11.59

URGN:

9.24

Total Revenue (TTM)

NUVB:

$143.05M

URGN:

$140.49M

Gross Profit (TTM)

NUVB:

$131.08M

URGN:

$126.24M

EBITDA (TTM)

NUVB:

-$139.03M

URGN:

-$117.04M

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Return for Risk

NUVB vs. URGN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

NUVB
NUVB Risk / Return Rank: 7171
Overall Rank
NUVB Sharpe Ratio Rank: 7272
Sharpe Ratio Rank
NUVB Sortino Ratio Rank: 7474
Sortino Ratio Rank
NUVB Omega Ratio Rank: 7575
Omega Ratio Rank
NUVB Calmar Ratio Rank: 7070
Calmar Ratio Rank
NUVB Martin Ratio Rank: 6565
Martin Ratio Rank

URGN
URGN Risk / Return Rank: 9797
Overall Rank
URGN Sharpe Ratio Rank: 9898
Sharpe Ratio Rank
URGN Sortino Ratio Rank: 9898
Sortino Ratio Rank
URGN Omega Ratio Rank: 9595
Omega Ratio Rank
URGN Calmar Ratio Rank: 9797
Calmar Ratio Rank
URGN Martin Ratio Rank: 9696
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

NUVB vs. URGN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Nuvation Bio Inc. (NUVB) and UroGen Pharma Ltd. (URGN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


NUVBURGNDifference

Sharpe ratio

Return per unit of total volatility

1.02

4.45

-3.43

Sortino ratio

Return per unit of downside risk

1.95

5.06

-3.10

Omega ratio

Gain probability vs. loss probability

1.27

1.59

-0.32

Calmar ratio

Return relative to maximum drawdown

1.62

10.32

-8.70

Martin ratio

Return relative to average drawdown

2.97

21.43

-18.46

NUVB vs. URGN - Sharpe Ratio Comparison

The current NUVB Sharpe Ratio is 1.02, which is lower than the URGN Sharpe Ratio of 4.45. The chart below compares the historical Sharpe Ratios of NUVB and URGN, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Sharpe Ratios by Period


NUVBURGNDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

1.02

4.45

-3.43

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

-0.23

0.09

-0.32

Sharpe Ratio (All Time)

Calculated using the full available price history

-0.17

0.09

-0.26

Drawdowns

NUVB vs. URGN - Drawdown Comparison

The maximum NUVB drawdown since its inception was -93.39%, roughly equal to the maximum URGN drawdown of -93.98%. Use the drawdown chart below to compare losses from any high point for NUVB and URGN.


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Drawdown Indicators


NUVBURGNDifference

Max Drawdown

Largest peak-to-trough decline

-93.39%

-93.98%

+0.59%

Max Drawdown (1Y)

Largest decline over 1 year

-57.55%

-42.22%

-15.33%

Max Drawdown (3Y)

Largest decline over 3 years

-58.19%

-82.64%

+24.45%

Max Drawdown (5Y)

Largest decline over 5 years

-92.88%

-82.64%

-10.24%

Current Drawdown

Current decline from peak

-67.60%

-59.28%

-8.32%

Average Drawdown

Average peak-to-trough decline

-65.50%

-61.55%

-3.95%

Ulcer Index

Depth and duration of drawdowns from previous peaks

31.33%

20.28%

+11.05%

Volatility

NUVB vs. URGN - Volatility Comparison

The current volatility for Nuvation Bio Inc. (NUVB) is 18.34%, while UroGen Pharma Ltd. (URGN) has a volatility of 20.26%. This indicates that NUVB experiences smaller price fluctuations and is considered to be less risky than URGN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


NUVBURGNDifference

Volatility (1M)

Calculated over the trailing 1-month period

18.34%

20.26%

-1.92%

Volatility (6M)

Calculated over the trailing 6-month period

52.92%

46.53%

+6.39%

Volatility (1Y)

Calculated over the trailing 1-year period

91.39%

97.85%

-6.46%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

75.57%

91.53%

-15.96%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

73.03%

79.56%

-6.53%

Dividends

NUVB vs. URGN - Dividend Comparison

Neither NUVB nor URGN has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

NUVB vs. URGN - Financials Comparison

This section allows you to compare key financial metrics between Nuvation Bio Inc. and UroGen Pharma Ltd.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.0020.00M40.00M60.00M80.00M20222023202420252026
83.23M
50.96M
(NUVB) Total Revenue
(URGN) Total Revenue
Values in USD except per share items

NUVB vs. URGN - Profitability Comparison

The chart below illustrates the profitability comparison between Nuvation Bio Inc. and UroGen Pharma Ltd. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

0.0%20.0%40.0%60.0%80.0%100.0%20222023202420252026
93.3%
91.9%
Portfolio components
NUVB - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Nuvation Bio Inc. reported a gross profit of 77.61M and revenue of 83.23M. Therefore, the gross margin over that period was 93.3%.

URGN - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, UroGen Pharma Ltd. reported a gross profit of 46.82M and revenue of 50.96M. Therefore, the gross margin over that period was 91.9%.

NUVB - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Nuvation Bio Inc. reported an operating income of 3.88M and revenue of 83.23M, resulting in an operating margin of 4.7%.

URGN - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, UroGen Pharma Ltd. reported an operating income of -20.26M and revenue of 50.96M, resulting in an operating margin of -39.8%.

NUVB - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Nuvation Bio Inc. reported a net income of 5.40M and revenue of 83.23M, resulting in a net margin of 6.5%.

URGN - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, UroGen Pharma Ltd. reported a net income of -23.57M and revenue of 50.96M, resulting in a net margin of -46.3%.


Frequently Asked Questions


NUVB and URGN have a correlation of 0.28, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

URGN has higher volatility (20.26%) compared to NUVB (18.34%). In terms of maximum drawdown, NUVB dropped -93.39% vs URGN's -93.98%.

URGN currently has the higher Sharpe Ratio (4.45 vs 1.02), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

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