XERS vs. BTC-USD

Last updated Apr 2, 2026

Compare and contrast key facts about Xeris Biopharma Holdings, Inc. (XERS) and Bitcoin (BTC-USD).

Performance

XERS vs. BTC-USD - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Xeris Biopharma Holdings, Inc. (XERS) and Bitcoin (BTC-USD). The values are adjusted to include any dividend payments, if applicable.

XERS vs. BTC-USD - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
XERS Xeris Biopharma Holdings, Inc.	-23.06%	131.56%	44.26%	76.69%	-54.61%	-40.45%	-30.21%	-58.53%	-15.92%
BTC-USD Bitcoin	-21.63%	-6.27%	120.76%	155.82%	-64.23%	59.40%	304.57%	94.10%	-45.05%

Returns By Period

In the year-to-date period, XERS achieves a -23.06% return, which is significantly lower than BTC-USD's -21.63% return.

XERS

• 1D: 4.14%
• 1M: 0.33%
• YTD: -23.06%
• 6M: -24.59%
• 1Y: 18.90%
• 3Y*: 54.74%
• 5Y*: 6.02%
• 10Y*: —

BTC-USD

• 1D: 0.51%
• 1M: -0.38%
• YTD: -21.63%
• 6M: -42.21%
• 1Y: -19.49%
• 3Y*: 34.49%
• 5Y*: 3.06%
• 10Y*: 66.45%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

XERS vs. BTC-USD — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

XERS

XERS Risk / Return Rank: 49
XERS Sharpe Ratio Rank: 52
XERS Sortino Ratio Rank: 52
XERS Omega Ratio Rank: 51
XERS Calmar Ratio Rank: 46
XERS Martin Ratio Rank: 46

BTC-USD

BTC-USD Risk / Return Rank: 43
BTC-USD Sharpe Ratio Rank: 61
BTC-USD Sortino Ratio Rank: 55
BTC-USD Omega Ratio Rank: 51
BTC-USD Calmar Ratio Rank: 43
BTC-USD Martin Ratio Rank: 4

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

XERS vs. BTC-USD - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Xeris Biopharma Holdings, Inc. (XERS) and Bitcoin (BTC-USD). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	XERS	BTC-USD	Difference
Sharpe ratio Return per unit of total volatility	0.31	-0.44	+0.75
Sortino ratio Return per unit of downside risk	0.89	-0.38	+1.27
Omega ratio Gain probability vs. loss probability	1.12	0.96	+0.16
Calmar ratio Return relative to maximum drawdown	0.22	-1.11	+1.32
Martin ratio Return relative to average drawdown	0.47	-1.99	+2.46
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

XERS vs. BTC-USD - Sharpe Ratio Comparison

The current XERS Sharpe Ratio is 0.31, which is higher than the BTC-USD Sharpe Ratio of -0.44. The chart below compares the historical Sharpe Ratios of XERS and BTC-USD, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	XERS	BTC-USD	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.31	-0.44	+0.75
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.09	0.05	+0.03
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.97	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.18	1.19	-1.37

Correlation

The correlation between XERS and BTC-USD is 0.13, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Drawdowns

XERS vs. BTC-USD - Drawdown Comparison

The maximum XERS drawdown since its inception was -96.22%, which is greater than BTC-USD's maximum drawdown of -85.30%. Use the drawdown chart below to compare losses from any high point for XERS and BTC-USD.

Drawdown Indicators

	XERS	BTC-USD	Difference
Max Drawdown Largest peak-to-trough decline	-96.22%	-85.30%	-10.92%
Max Drawdown (1Y) Largest decline over 1 year	-46.57%	-49.65%	+3.08%
Max Drawdown (5Y) Largest decline over 5 years	-78.59%	-76.67%	-1.92%
Max Drawdown (10Y) Largest decline over 10 years	—	-83.80%	—
Current Drawdown Current decline from peak	-77.82%	-45.02%	-32.80%
Average Drawdown Average peak-to-trough decline	-79.09%	-41.99%	-37.10%
Ulcer Index Depth and duration of drawdowns from previous peaks	21.19%	27.60%	-6.41%

Volatility

XERS vs. BTC-USD - Volatility Comparison

Xeris Biopharma Holdings, Inc. (XERS) has a higher volatility of 15.22% compared to Bitcoin (BTC-USD) at 13.58%. This indicates that XERS's price experiences larger fluctuations and is considered to be riskier than BTC-USD based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	XERS	BTC-USD	Difference
Volatility (1M) Calculated over the trailing 1-month period	15.22%	13.58%	+1.64%
Volatility (6M) Calculated over the trailing 6-month period	43.33%	35.98%	+7.35%
Volatility (1Y) Calculated over the trailing 1-year period	61.79%	36.76%	+25.03%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	69.47%	46.90%	+22.57%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	79.84%	56.70%	+23.14%