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NUVB vs. ESPR
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Performance

NUVB vs. ESPR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Nuvation Bio Inc. (NUVB) and Esperion Therapeutics, Inc. (ESPR). The values are adjusted to include any dividend payments, if applicable.

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NUVB vs. ESPR - Yearly Performance Comparison


2026 (YTD)202520242023202220212020
NUVB
Nuvation Bio Inc.
-52.12%236.84%76.16%-21.35%-77.41%-27.35%17.00%
ESPR
Esperion Therapeutics, Inc.
-25.95%68.18%-26.42%-52.01%24.60%-80.77%-16.61%

Fundamentals

Market Cap

NUVB:

$1.48B

ESPR:

$779.73M

EPS

NUVB:

-$0.60

ESPR:

-$0.10

PS Ratio

NUVB:

23.36

ESPR:

1.54

Total Revenue (TTM)

NUVB:

$62.90M

ESPR:

$403.14M

Gross Profit (TTM)

NUVB:

$54.46M

ESPR:

$119.19M

EBITDA (TTM)

NUVB:

-$199.90M

ESPR:

$62.77M

Returns By Period

In the year-to-date period, NUVB achieves a -52.12% return, which is significantly lower than ESPR's -25.95% return.


NUVB

1D
5.93%
1M
-27.41%
YTD
-52.12%
6M
15.95%
1Y
143.75%
3Y*
37.23%
5Y*
-15.90%
10Y*

ESPR

1D
4.18%
1M
-18.21%
YTD
-25.95%
6M
3.40%
1Y
90.28%
3Y*
19.89%
5Y*
-37.49%
10Y*
-16.92%
*Multi-year figures are annualized to reflect compound growth (CAGR)

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Nuvation Bio Inc.

Esperion Therapeutics, Inc.

Return for Risk

NUVB vs. ESPR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

NUVB
NUVB Risk / Return Rank: 8383
Overall Rank
NUVB Sharpe Ratio Rank: 8585
Sharpe Ratio Rank
NUVB Sortino Ratio Rank: 8484
Sortino Ratio Rank
NUVB Omega Ratio Rank: 8484
Omega Ratio Rank
NUVB Calmar Ratio Rank: 8181
Calmar Ratio Rank
NUVB Martin Ratio Rank: 8080
Martin Ratio Rank

ESPR
ESPR Risk / Return Rank: 7474
Overall Rank
ESPR Sharpe Ratio Rank: 7777
Sharpe Ratio Rank
ESPR Sortino Ratio Rank: 7676
Sortino Ratio Rank
ESPR Omega Ratio Rank: 7171
Omega Ratio Rank
ESPR Calmar Ratio Rank: 7474
Calmar Ratio Rank
ESPR Martin Ratio Rank: 7272
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

NUVB vs. ESPR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Nuvation Bio Inc. (NUVB) and Esperion Therapeutics, Inc. (ESPR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


NUVBESPRDifference

Sharpe ratio

Return per unit of total volatility

1.52

1.09

+0.43

Sortino ratio

Return per unit of downside risk

2.35

1.85

+0.51

Omega ratio

Gain probability vs. loss probability

1.32

1.22

+0.11

Calmar ratio

Return relative to maximum drawdown

2.36

1.68

+0.68

Martin ratio

Return relative to average drawdown

5.83

3.82

+2.00

NUVB vs. ESPR - Sharpe Ratio Comparison

The current NUVB Sharpe Ratio is 1.52, which is higher than the ESPR Sharpe Ratio of 1.09. The chart below compares the historical Sharpe Ratios of NUVB and ESPR, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


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Sharpe Ratios by Period


NUVBESPRDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

1.52

1.09

+0.43

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

-0.21

-0.42

+0.21

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

-0.20

Sharpe Ratio (All Time)

Calculated using the full available price history

-0.19

-0.15

-0.04

Correlation

The correlation between NUVB and ESPR is 0.30, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


Dividends

NUVB vs. ESPR - Dividend Comparison

Neither NUVB nor ESPR has paid dividends to shareholders.


Tickers have no history of dividend payments

Drawdowns

NUVB vs. ESPR - Drawdown Comparison

The maximum NUVB drawdown since its inception was -93.39%, smaller than the maximum ESPR drawdown of -99.37%. Use the drawdown chart below to compare losses from any high point for NUVB and ESPR.


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Drawdown Indicators


NUVBESPRDifference

Max Drawdown

Largest peak-to-trough decline

-93.39%

-99.37%

+5.98%

Max Drawdown (1Y)

Largest decline over 1 year

-57.55%

-48.23%

-9.32%

Max Drawdown (5Y)

Largest decline over 5 years

-93.35%

-97.46%

+4.11%

Max Drawdown (10Y)

Largest decline over 10 years

-99.10%

Current Drawdown

Current decline from peak

-70.56%

-97.62%

+27.06%

Average Drawdown

Average peak-to-trough decline

-65.43%

-69.54%

+4.11%

Ulcer Index

Depth and duration of drawdowns from previous peaks

23.29%

21.62%

+1.67%

Volatility

NUVB vs. ESPR - Volatility Comparison

Nuvation Bio Inc. (NUVB) has a higher volatility of 33.02% compared to Esperion Therapeutics, Inc. (ESPR) at 27.56%. This indicates that NUVB's price experiences larger fluctuations and is considered to be riskier than ESPR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


NUVBESPRDifference

Volatility (1M)

Calculated over the trailing 1-month period

33.02%

27.56%

+5.46%

Volatility (6M)

Calculated over the trailing 6-month period

70.37%

57.36%

+13.01%

Volatility (1Y)

Calculated over the trailing 1-year period

95.01%

83.33%

+11.68%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

75.97%

89.13%

-13.16%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

73.55%

83.10%

-9.55%

Financials

NUVB vs. ESPR - Financials Comparison

This section allows you to compare key financial metrics between Nuvation Bio Inc. and Esperion Therapeutics, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.0050.00M100.00M150.00MAprilJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025AprilJulyOctober
41.87M
168.45M
(NUVB) Total Revenue
(ESPR) Total Revenue
Values in USD except per share items

NUVB vs. ESPR - Profitability Comparison

The chart below illustrates the profitability comparison between Nuvation Bio Inc. and Esperion Therapeutics, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

0.0%20.0%40.0%60.0%80.0%100.0%AprilJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025AprilJulyOctober
99.0%
0
Portfolio components
NUVB - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Nuvation Bio Inc. reported a gross profit of 41.44M and revenue of 41.87M. Therefore, the gross margin over that period was 99.0%.

ESPR - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Esperion Therapeutics, Inc. reported a gross profit of 0.00 and revenue of 168.45M. Therefore, the gross margin over that period was 0.0%.

NUVB - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Nuvation Bio Inc. reported an operating income of -34.04M and revenue of 41.87M, resulting in an operating margin of -81.3%.

ESPR - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Esperion Therapeutics, Inc. reported an operating income of 85.23M and revenue of 168.45M, resulting in an operating margin of 50.6%.

NUVB - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Nuvation Bio Inc. reported a net income of -36.59M and revenue of 41.87M, resulting in a net margin of -87.4%.

ESPR - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Esperion Therapeutics, Inc. reported a net income of 61.83M and revenue of 168.45M, resulting in a net margin of 36.7%.