NICE vs. NBIX
NICE (NICE Ltd.) and NBIX (Neurocrine Biosciences, Inc.) are both stocks. NICE operates in Software - Application (Technology), while NBIX operates in Drug Manufacturers - Specialty & Generic (Healthcare). Over the past 10 years, NICE returned 4.49%/yr vs 13.85%/yr for NBIX. At a 0.22 correlation, their price movements are largely independent.
Performance
NICE vs. NBIX - Performance Comparison
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Returns By Period
In the year-to-date period, NICE achieves a -11.77% return, which is significantly lower than NBIX's 24.87% return. Over the past 10 years, NICE has underperformed NBIX with an annualized return of 4.49%, while NBIX has yielded a comparatively higher 13.85% annualized return.
NICE
- 1D
- 1.92%
- 1M
- 13.24%
- 6M
- -14.80%
- YTD
- -11.77%
- 1Y
- -35.59%
- 3Y*
- -21.22%
- 5Y*
- -17.19%
- 10Y*
- 4.49%
NBIX
- 1D
- -1.91%
- 1M
- 8.85%
- 6M
- 30.43%
- YTD
- 24.87%
- 1Y
- 32.71%
- 3Y*
- 21.73%
- 5Y*
- 12.33%
- 10Y*
- 13.85%
NICE vs. NBIX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
NICE NICE Ltd. | -11.77% | -33.44% | -14.87% | 3.75% | -36.66% | 7.07% | 82.75% | 43.38% | 17.73% | 33.92% |
NBIX Neurocrine Biosciences, Inc. | 24.87% | 3.90% | 3.60% | 10.31% | 40.24% | -11.14% | -10.83% | 50.53% | -7.96% | 100.49% |
Correlation
The correlation between NICE and NBIX is 0.06, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.06 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.11 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.16 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.21 |
Correlation (All Time) Calculated using the full available price history since May 23, 1996 | 0.22 |
The correlation between NICE and NBIX shifts across timeframes, from 0.06 (1 year) to 0.22 (all time), reflecting how their relationship changes across market environments.
Fundamentals
NICE:
$5.84B
NBIX:
$17.81B
NICE:
$8.52
NBIX:
$6.50
NICE:
11.70
NBIX:
27.23
NICE:
0.35
NBIX:
0.54
NICE:
2.06
NBIX:
5.87
NICE:
1.64
NBIX:
5.37
NICE:
$3.01B
NBIX:
$3.10B
NICE:
$1.98B
NBIX:
$3.05B
NICE:
$841.27M
NBIX:
$881.20M
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Return for Risk
NICE vs. NBIX — Risk / Return Rank
NICE
NBIX
NICE vs. NBIX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for NICE Ltd. (NICE) and Neurocrine Biosciences, Inc. (NBIX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| NICE | NBIX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.75 | ||
| Sortino ratioReturn per unit of downside risk | -2.38 | ||
| Omega ratioGain probability vs. loss probability | 0.87 | 1.20 | -0.33 |
| Calmar ratioReturn relative to maximum drawdown | -0.76 | 1.50 | -2.26 |
| Martin ratioReturn relative to average drawdown | -1.20 | 3.29 | -4.49 |
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Drawdowns
NICE vs. NBIX - Drawdown Comparison
The maximum NICE drawdown since its inception was -93.23%, roughly equal to the maximum NBIX drawdown of -97.21%. Use the drawdown chart below to compare losses from any high point for NICE and NBIX.
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Drawdown Indicators
| NICE | NBIX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -93.23% | -97.21% | +3.98% |
Max Drawdown (1Y)Largest decline over 1 year | -51.19% | -20.90% | -30.29% |
Max Drawdown (3Y)Largest decline over 3 years | -68.21% | -42.89% | -25.32% |
Max Drawdown (5Y)Largest decline over 5 years | -73.60% | -42.89% | -30.71% |
Max Drawdown (10Y)Largest decline over 10 years | -73.60% | -46.39% | -27.21% |
Current DrawdownCurrent decline from peak | -68.34% | -1.91% | -66.43% |
Average DrawdownAverage peak-to-trough decline | -35.27% | -43.74% | +8.47% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 32.47% | 9.52% | +22.95% |
Volatility
NICE vs. NBIX - Volatility Comparison
NICE Ltd. (NICE) has a higher volatility of 10.16% compared to Neurocrine Biosciences, Inc. (NBIX) at 8.08%. This indicates that NICE's price experiences larger fluctuations and is considered to be riskier than NBIX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| NICE | NBIX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 10.16% | 8.08% | +2.08% |
Volatility (6M)Calculated over the trailing 6-month period | 42.52% | 23.42% | +19.10% |
Volatility (1Y)Calculated over the trailing 1-year period | 51.48% | 31.73% | +19.75% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 39.92% | 32.83% | +7.09% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 33.27% | 39.03% | -5.76% |
Dividends
NICE vs. NBIX - Dividend Comparison
Neither NICE nor NBIX has paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
NBIX Neurocrine Biosciences, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
NICE NICE Ltd. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.14% | 0.76% | 0.91% |
Financials
NICE vs. NBIX - Financials Comparison
This section allows you to compare key financial metrics between NICE Ltd. and Neurocrine Biosciences, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
NICE vs. NBIX - Profitability Comparison
NICE - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jul 2026, NICE Ltd. reported a gross profit of 493.46M and revenue of 766.53M. Therefore, the gross margin over that period was 64.4%.
NBIX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported a gross profit of 800.70M and revenue of 814.50M. Therefore, the gross margin over that period was 98.3%.
NICE - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jul 2026, NICE Ltd. reported an operating income of 126.41M and revenue of 766.53M, resulting in an operating margin of 16.5%.
NBIX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported an operating income of 193.40M and revenue of 814.50M, resulting in an operating margin of 23.7%.
NICE - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jul 2026, NICE Ltd. reported a net income of 46.69M and revenue of 766.53M, resulting in a net margin of 6.1%.
NBIX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported a net income of 197.90M and revenue of 814.50M, resulting in a net margin of 24.3%.
Frequently Asked Questions
NICE and NBIX have a correlation of 0.06, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
NICE has higher volatility (10.16%) compared to NBIX (8.08%). In terms of maximum drawdown, NICE dropped -93.23% vs NBIX's -97.21%.
NBIX currently has the higher Sharpe Ratio (0.99 vs -0.76), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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