NBIX vs. TCOM
NBIX (Neurocrine Biosciences, Inc.) and TCOM (Trip.com Group Limited) are both stocks. NBIX operates in Drug Manufacturers - Specialty & Generic (Healthcare), while TCOM operates in Travel Services (Consumer Cyclical). Over the past 10 years, NBIX returned 13.85%/yr vs 0.25%/yr for TCOM. At a 0.23 correlation, their price movements are largely independent.
Performance
NBIX vs. TCOM - Performance Comparison
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Returns By Period
In the year-to-date period, NBIX achieves a 24.87% return, which is significantly higher than TCOM's -40.48% return. Over the past 10 years, NBIX has outperformed TCOM with an annualized return of 13.85%, while TCOM has yielded a comparatively lower 0.25% annualized return.
NBIX
- 1D
- -1.91%
- 1M
- 8.85%
- 6M
- 30.43%
- YTD
- 24.87%
- 1Y
- 32.71%
- 3Y*
- 21.73%
- 5Y*
- 12.33%
- 10Y*
- 13.85%
TCOM
- 1D
- 3.31%
- 1M
- -9.69%
- 6M
- -43.43%
- YTD
- -40.48%
- 1Y
- -30.88%
- 3Y*
- 6.23%
- 5Y*
- 5.97%
- 10Y*
- 0.25%
NBIX vs. TCOM - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
NBIX Neurocrine Biosciences, Inc. | 24.87% | 3.90% | 3.60% | 10.31% | 40.24% | -11.14% | -10.83% | 50.53% | -7.96% | 100.49% |
TCOM Trip.com Group Limited | -40.48% | 5.24% | 90.67% | 4.68% | 39.72% | -27.01% | 0.57% | 23.95% | -38.64% | 10.25% |
Correlation
The correlation between NBIX and TCOM is 0.06, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.06 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.12 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.17 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.21 |
Correlation (All Time) Calculated using the full available price history since Dec 9, 2003 | 0.23 |
The correlation between NBIX and TCOM shifts across timeframes, from 0.06 (1 year) to 0.23 (all time), reflecting how their relationship changes across market environments.
Fundamentals
NBIX:
$17.81B
TCOM:
$26.95B
NBIX:
$6.50
TCOM:
CN¥45.41
NBIX:
27.23
TCOM:
6.39
NBIX:
0.54
TCOM:
0.04
NBIX:
5.87
TCOM:
3.12
NBIX:
5.37
TCOM:
1.20
NBIX:
$3.10B
TCOM:
CN¥64.48B
NBIX:
$3.05B
TCOM:
CN¥51.79B
NBIX:
$881.20M
TCOM:
CN¥39.20B
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Return for Risk
NBIX vs. TCOM — Risk / Return Rank
NBIX
TCOM
NBIX vs. TCOM - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Neurocrine Biosciences, Inc. (NBIX) and Trip.com Group Limited (TCOM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| NBIX | TCOM | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.80 | ||
| Sortino ratioReturn per unit of downside risk | +2.50 | ||
| Omega ratioGain probability vs. loss probability | 1.20 | 0.85 | +0.35 |
| Calmar ratioReturn relative to maximum drawdown | 1.50 | -0.62 | +2.13 |
| Martin ratioReturn relative to average drawdown | 3.29 | -1.24 | +4.53 |
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Drawdowns
NBIX vs. TCOM - Drawdown Comparison
The maximum NBIX drawdown since its inception was -97.21%, which is greater than TCOM's maximum drawdown of -76.34%. Use the drawdown chart below to compare losses from any high point for NBIX and TCOM.
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Drawdown Indicators
| NBIX | TCOM | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -97.21% | -76.34% | -20.87% |
Max Drawdown (1Y)Largest decline over 1 year | -20.90% | -49.54% | +28.64% |
Max Drawdown (3Y)Largest decline over 3 years | -42.89% | -49.54% | +6.65% |
Max Drawdown (5Y)Largest decline over 5 years | -42.89% | -49.54% | +6.65% |
Max Drawdown (10Y)Largest decline over 10 years | -46.39% | -71.96% | +25.57% |
Current DrawdownCurrent decline from peak | -1.91% | -45.80% | +43.89% |
Average DrawdownAverage peak-to-trough decline | -43.74% | -27.89% | -15.85% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 9.52% | 24.98% | -15.46% |
Volatility
NBIX vs. TCOM - Volatility Comparison
The current volatility for Neurocrine Biosciences, Inc. (NBIX) is 8.08%, while Trip.com Group Limited (TCOM) has a volatility of 16.28%. This indicates that NBIX experiences smaller price fluctuations and is considered to be less risky than TCOM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| NBIX | TCOM | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 8.08% | 16.28% | -8.20% |
Volatility (6M)Calculated over the trailing 6-month period | 23.42% | 31.02% | -7.60% |
Volatility (1Y)Calculated over the trailing 1-year period | 31.73% | 38.00% | -6.27% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 32.83% | 49.47% | -16.64% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 39.03% | 44.42% | -5.39% |
Dividends
NBIX vs. TCOM - Dividend Comparison
Neither NBIX nor TCOM has paid dividends to shareholders.
| Position | TTM | 2025 |
|---|---|---|
NBIX Neurocrine Biosciences, Inc. | 0.00% | 0.00% |
TCOM Trip.com Group Limited | 0.00% | 0.42% |
Financials
NBIX vs. TCOM - Financials Comparison
This section allows you to compare key financial metrics between Neurocrine Biosciences, Inc. and Trip.com Group Limited. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
NBIX vs. TCOM - Profitability Comparison
NBIX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported a gross profit of 800.70M and revenue of 814.50M. Therefore, the gross margin over that period was 98.3%.
TCOM - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jul 2026, Trip.com Group Limited reported a gross profit of 12.80B and revenue of 16.11B. Therefore, the gross margin over that period was 79.5%.
NBIX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported an operating income of 193.40M and revenue of 814.50M, resulting in an operating margin of 23.7%.
TCOM - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jul 2026, Trip.com Group Limited reported an operating income of 3.92B and revenue of 16.11B, resulting in an operating margin of 24.3%.
NBIX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jul 2026, Neurocrine Biosciences, Inc. reported a net income of 197.90M and revenue of 814.50M, resulting in a net margin of 24.3%.
TCOM - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jul 2026, Trip.com Group Limited reported a net income of 2.48B and revenue of 16.11B, resulting in a net margin of 15.4%.
Frequently Asked Questions
NBIX and TCOM have a correlation of 0.06, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
TCOM has higher volatility (16.28%) compared to NBIX (8.08%). In terms of maximum drawdown, NBIX dropped -97.21% vs TCOM's -76.34%.
NBIX currently has the higher Sharpe Ratio (0.99 vs -0.81), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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