NBIX vs. TCOM
NBIX (Neurocrine Biosciences, Inc.) and TCOM (Trip.com Group Limited) are both stocks. NBIX operates in Drug Manufacturers - Specialty & Generic (Healthcare), while TCOM operates in Travel Services (Consumer Cyclical). Over the past 10 years, NBIX returned 12.71%/yr vs 1.05%/yr for TCOM. Their 0.23 correlation means their historical movements had little consistent relationship.
Performance
NBIX vs. TCOM - Performance Comparison
Loading charts...
Returns By Period
In the year-to-date period, NBIX achieves a 17.61% return, which is significantly higher than TCOM's -34.63% return. Over the past 10 years, NBIX has outperformed TCOM with an annualized return of 12.71%, while TCOM has yielded a comparatively lower 1.05% annualized return.
NBIX
- 1D
- -10.08%
- 1M
- -0.58%
- 6M
- 22.59%
- YTD
- 17.61%
- 1Y
- 30.08%
- 3Y*
- 17.27%
- 5Y*
- 12.34%
- 10Y*
- 12.71%
- ALL TIME*
- 9.11%
TCOM
- 1D
- 1.14%
- 1M
- 14.44%
- 6M
- -23.40%
- YTD
- -34.63%
- 1Y
- -24.12%
- 3Y*
- 5.39%
- 5Y*
- 12.75%
- 10Y*
- 1.05%
- ALL TIME*
- 16.55%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $278.93M | $232.17M | $211.02M | |
| $161.73M | $136.85M | $152.49M |
NBIX vs. TCOM - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
NBIX Neurocrine Biosciences, Inc. | 17.61% | 3.90% | 3.60% | 10.31% | 40.24% | -11.14% | -10.83% | 50.53% | -7.96% | 100.49% |
TCOM Trip.com Group Limited | -34.63% | 5.24% | 90.67% | 4.68% | 39.72% | -27.01% | 0.57% | 23.95% | -38.64% | 10.25% |
Correlation
The correlation between NBIX and TCOM is 0.11, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.11 |
Correlation (3Y) Balances recent behavior with more history. | 0.13 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.17 |
Correlation (10Y) Provides a long-term view across more market conditions. | 0.21 |
Correlation (All Time) Calculated using the full available price history since Dec 9, 2003 | 0.23 |
The correlation between NBIX and TCOM shifts across timeframes, from 0.11 (1 year) to 0.23 (all time), reflecting how their relationship changes across market environments.
Fundamentals
NBIX:
$16.77B
TCOM:
$29.60B
NBIX:
$6.84
TCOM:
CN¥45.41
NBIX:
24.39
TCOM:
6.99
NBIX:
0.48
TCOM:
0.04
NBIX:
5.10
TCOM:
3.41
NBIX:
4.35
TCOM:
1.32
NBIX:
$3.37B
TCOM:
CN¥64.48B
NBIX:
$3.31B
TCOM:
CN¥51.79B
NBIX:
$940.50M
TCOM:
CN¥39.20B
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
Return for Risk
NBIX vs. TCOM — Risk / Return Rank
NBIX
TCOM
NBIX vs. TCOM - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Neurocrine Biosciences, Inc. (NBIX) and Trip.com Group Limited (TCOM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| NBIX | TCOM | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.54 | ||
| Sortino ratioReturn per unit of downside risk | +2.06 | ||
| Omega ratioGain probability vs. loss probability | 1.19 | 0.90 | +0.29 |
| Calmar ratioReturn relative to maximum drawdown | 1.45 | -0.49 | +1.93 |
| Martin ratioReturn relative to average drawdown | 3.18 | -0.89 | +4.07 |
Loading charts...
Drawdowns
NBIX vs. TCOM - Drawdown Comparison
The maximum NBIX drawdown since its inception was -97.21%, which is greater than TCOM's maximum drawdown of -76.34%. Use the drawdown chart below to compare losses from any high point for NBIX and TCOM.
Loading charts...
Drawdown Indicators
| NBIX | TCOM | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -97.21% | -76.34% | -20.87% |
Max Drawdown (1Y)Largest decline over 1 year | -20.90% | -49.54% | +28.64% |
Max Drawdown (3Y)Largest decline over 3 years | -42.89% | -49.54% | +6.65% |
Max Drawdown (5Y)Largest decline over 5 years | -42.89% | -49.54% | +6.65% |
Max Drawdown (10Y)Largest decline over 10 years | -46.39% | -71.96% | +25.57% |
Current DrawdownCurrent decline from peak | -10.08% | -40.46% | +30.38% |
Average DrawdownAverage peak-to-trough decline | -43.66% | -27.93% | -15.73% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 9.47% | 27.19% | -17.72% |
Volatility
NBIX vs. TCOM - Volatility Comparison
Neurocrine Biosciences, Inc. (NBIX) has a higher volatility of 14.12% compared to Trip.com Group Limited (TCOM) at 7.88%. This indicates that NBIX's price experiences larger fluctuations and is considered to be riskier than TCOM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading charts...
Volatility by Period
| NBIX | TCOM | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 14.12% | 7.88% | +6.24% |
Volatility (6M)Calculated over the trailing 6-month period | 26.01% | 24.85% | +1.16% |
Volatility (1Y)Calculated over the trailing 1-year period | 33.74% | 38.45% | -4.71% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 33.17% | 49.11% | -15.94% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 39.18% | 44.47% | -5.29% |
Dividends
NBIX vs. TCOM - Dividend Comparison
Neither NBIX nor TCOM has paid dividends to shareholders.
| Position | TTM | 2025 |
|---|---|---|
NBIX Neurocrine Biosciences, Inc. | 0.00% | 0.00% |
TCOM Trip.com Group Limited | 0.00% | 0.42% |
Financials
NBIX vs. TCOM - Financials Comparison
This section allows you to compare key financial metrics between Neurocrine Biosciences, Inc. and Trip.com Group Limited. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
NBIX vs. TCOM - Profitability Comparison
NBIX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Neurocrine Biosciences, Inc. reported a gross profit of 935.80M and revenue of 959.00M. Therefore, the gross margin over that period was 97.6%.
TCOM - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Trip.com Group Limited reported a gross profit of 12.80B and revenue of 16.11B. Therefore, the gross margin over that period was 79.5%.
NBIX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Neurocrine Biosciences, Inc. reported an operating income of 151.50M and revenue of 959.00M, resulting in an operating margin of 15.8%.
TCOM - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Trip.com Group Limited reported an operating income of 3.92B and revenue of 16.11B, resulting in an operating margin of 24.3%.
NBIX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Neurocrine Biosciences, Inc. reported a net income of 144.40M and revenue of 959.00M, resulting in a net margin of 15.1%.
TCOM - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Trip.com Group Limited reported a net income of 2.48B and revenue of 16.11B, resulting in a net margin of 15.4%.
Frequently Asked Questions
NBIX and TCOM have a correlation of 0.11, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
NBIX has higher volatility (14.12%) compared to TCOM (7.88%). In terms of maximum drawdown, NBIX dropped -97.21% vs TCOM's -76.34%.
NBIX currently has the higher Sharpe Ratio (0.91 vs -0.63), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
Find the right allocation for NBIX and TCOM
Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.
Open Portfolio Optimizer