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ASML vs. NBIX
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

ASML vs. NBIX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in ASML Holding N.V. (ASML) and Neurocrine Biosciences, Inc. (NBIX). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, ASML achieves a 53.00% return, which is significantly higher than NBIX's 17.61% return. Over the past 10 years, ASML has outperformed NBIX with an annualized return of 32.27%, while NBIX has yielded a comparatively lower 12.71% annualized return.


ASML

1D
-1.36%
1M
-11.50%
6M
15.03%
YTD
53.00%
1Y
136.03%
3Y*
33.26%
5Y*
17.48%
10Y*
32.27%
ALL TIME*
26.74%

NBIX

1D
-10.08%
1M
-0.58%
6M
22.59%
YTD
17.61%
1Y
30.08%
3Y*
17.27%
5Y*
12.34%
10Y*
12.71%
ALL TIME*
9.11%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison


PositionAvg. Volume Value (2W)Avg. Volume Value (1M)Avg. Volume Value (3M)
$3.24B$3.55B$3.45B
$278.93M$232.17M$211.02M

ASML vs. NBIX - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
ASML
ASML Holding N.V.
53.00%56.51%-7.70%39.91%-30.49%64.13%66.06%93.56%-9.80%56.23%
NBIX
Neurocrine Biosciences, Inc.
17.61%3.90%3.60%10.31%40.24%-11.14%-10.83%50.53%-7.96%100.49%

Correlation

The correlation between ASML and NBIX is 0.17, which is low. Their historical price movements had little consistent relationship.


Correlation
Correlation (1Y)
Focuses on recent behavior, but can change the most.

0.17

Correlation (3Y)
Balances recent behavior with more history.

0.18

Correlation (5Y)
Shows whether the relationship held over a longer period.

0.18

Correlation (10Y)
Provides a long-term view across more market conditions.

0.24

Correlation (All Time)
Calculated using the full available price history since May 23, 1996

0.27

Fundamentals

Market Cap

ASML:

$627.85B

NBIX:

$16.77B

EPS

ASML:

€27.54

NBIX:

$6.84

PE Ratio

ASML:

51.36

NBIX:

24.39

PEG Ratio

ASML:

3.38

NBIX:

0.48

PS Ratio

ASML:

15.47

NBIX:

5.10

PB Ratio

ASML:

24.94

NBIX:

4.35

Total Revenue (TTM)

ASML:

€35.33B

NBIX:

$3.37B

Gross Profit (TTM)

ASML:

€18.63B

NBIX:

$3.31B

EBITDA (TTM)

ASML:

€13.77B

NBIX:

$940.50M

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Return for Risk

ASML vs. NBIX — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

ASML
ASML Risk / Return Rank: 9696
Overall Rank
ASML Sharpe Ratio Rank: 9797
Sharpe Ratio Rank
ASML Sortino Ratio Rank: 9595
Sortino Ratio Rank
ASML Omega Ratio Rank: 9393
Omega Ratio Rank
ASML Calmar Ratio Rank: 9797
Calmar Ratio Rank
ASML Martin Ratio Rank: 9898
Martin Ratio Rank

NBIX
NBIX Risk / Return Rank: 7171
Overall Rank
NBIX Sharpe Ratio Rank: 7474
Sharpe Ratio Rank
NBIX Sortino Ratio Rank: 6868
Sortino Ratio Rank
NBIX Omega Ratio Rank: 7070
Omega Ratio Rank
NBIX Calmar Ratio Rank: 7373
Calmar Ratio Rank
NBIX Martin Ratio Rank: 7171
Martin Ratio Rank
The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

ASML vs. NBIX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for ASML Holding N.V. (ASML) and Neurocrine Biosciences, Inc. (NBIX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


ASMLNBIXDifference
Sharpe ratioReturn per unit of total volatility

+2.07

Sortino ratioReturn per unit of downside risk

+1.99

Omega ratioGain probability vs. loss probability

1.41

1.19

+0.21

Calmar ratioReturn relative to maximum drawdown

6.23

1.45

+4.79

Martin ratioReturn relative to average drawdown

21.34

3.18

+18.15

ASML vs. NBIX - Sharpe Ratio Comparison

The current ASML Sharpe Ratio is 2.98, which is higher than the NBIX Sharpe Ratio of 0.91. The chart below compares the historical Sharpe Ratios of ASML and NBIX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

ASML vs. NBIX - Drawdown Comparison

The maximum ASML drawdown since its inception was -90.00%, smaller than the maximum NBIX drawdown of -97.21%. Use the drawdown chart below to compare losses from any high point for ASML and NBIX.


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Drawdown Indicators


ASMLNBIXDifference

Max Drawdown

Largest peak-to-trough decline

-90.00%

-97.21%

+7.21%

Max Drawdown (1Y)

Largest decline over 1 year

-21.95%

-20.90%

-1.05%

Max Drawdown (3Y)

Largest decline over 3 years

-45.38%

-42.89%

-2.49%

Max Drawdown (5Y)

Largest decline over 5 years

-56.84%

-42.89%

-13.95%

Max Drawdown (10Y)

Largest decline over 10 years

-56.84%

-46.39%

-10.45%

Current Drawdown

Current decline from peak

-18.01%

-10.08%

-7.93%

Average Drawdown

Average peak-to-trough decline

-28.04%

-43.66%

+15.62%

Ulcer Index

Depth and duration of drawdowns from previous peaks

6.40%

9.47%

-3.07%

Volatility

ASML vs. NBIX - Volatility Comparison

ASML Holding N.V. (ASML) and Neurocrine Biosciences, Inc. (NBIX) have volatilities of 14.49% and 14.12%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


ASMLNBIXDifference

Volatility (1M)

Calculated over the trailing 1-month period

14.49%

14.12%

+0.37%

Volatility (6M)

Calculated over the trailing 6-month period

37.32%

26.01%

+11.31%

Volatility (1Y)

Calculated over the trailing 1-year period

46.08%

33.74%

+12.34%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

43.25%

33.17%

+10.08%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

39.13%

39.18%

-0.05%

Dividends

ASML vs. NBIX - Dividend Comparison

ASML's dividend yield for the trailing twelve months is around 0.56%, while NBIX has not paid dividends to shareholders.


PositionTTM20252024202320222021202020192018201720162015
ASML
ASML Holding N.V.
0.56%0.97%0.97%0.86%1.27%0.50%0.50%1.40%0.94%0.64%0.92%0.73%
NBIX
Neurocrine Biosciences, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%

Financials

ASML vs. NBIX - Financials Comparison

This section allows you to compare key financial metrics between ASML Holding N.V. and Neurocrine Biosciences, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items

ASML vs. NBIX - Profitability Comparison

The chart below illustrates the profitability comparison between ASML Holding N.V. and Neurocrine Biosciences, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

ASML - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, ASML Holding N.V. reported a gross profit of 5.04B and revenue of 9.33B. Therefore, the gross margin over that period was 54.0%.

NBIX - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Neurocrine Biosciences, Inc. reported a gross profit of 935.80M and revenue of 959.00M. Therefore, the gross margin over that period was 97.6%.

ASML - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, ASML Holding N.V. reported an operating income of 3.46B and revenue of 9.33B, resulting in an operating margin of 37.1%.

NBIX - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Neurocrine Biosciences, Inc. reported an operating income of 151.50M and revenue of 959.00M, resulting in an operating margin of 15.8%.

ASML - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, ASML Holding N.V. reported a net income of 2.92B and revenue of 9.33B, resulting in a net margin of 31.3%.

NBIX - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Neurocrine Biosciences, Inc. reported a net income of 144.40M and revenue of 959.00M, resulting in a net margin of 15.1%.


Frequently Asked Questions


ASML and NBIX have a correlation of 0.17, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

ASML has higher volatility (14.49%) compared to NBIX (14.12%). In terms of maximum drawdown, ASML dropped -90.00% vs NBIX's -97.21%.

ASML currently has the higher Sharpe Ratio (2.98 vs 0.91), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

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