APH vs. ANAB

Last updated Jun 13, 2026

APH (Amphenol Corporation) and ANAB (AnaptysBio, Inc.) are both stocks. APH operates in Electronic Components (Technology), while ANAB operates in Biotechnology (Healthcare). Over the past 5 years, APH returned 36.37%/yr vs 28.21%/yr for ANAB. At a 0.22 correlation, their price movements are largely independent.

Performance

APH vs. ANAB - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Amphenol Corporation (APH) and AnaptysBio, Inc. (ANAB). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, APH achieves a 14.03% return, which is significantly lower than ANAB's 73.48% return.

APH

• 1D: 0.88%
• 1M: 23.40%
• YTD: 14.03%
• 6M: 19.47%
• 1Y: 63.73%
• 3Y*: 57.45%
• 5Y*: 36.37%
• 10Y*: 27.74%

ANAB

• 1D: 3.37%
• 1M: -10.55%
• YTD: 73.48%
• 6M: 87.15%
• 1Y: 259.27%
• 3Y*: 64.14%
• 5Y*: 28.21%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

APH vs. ANAB - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
APH Amphenol Corporation	14.03%	96.08%	41.30%	31.85%	-11.96%	35.25%	22.09%	34.91%	-6.82%	32.14%
ANAB AnaptysBio, Inc.	73.48%	266.16%	-38.19%	-30.88%	-10.82%	61.63%	32.31%	-74.53%	-36.67%	529.50%

Correlation

The correlation between APH and ANAB is 0.09, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.09
Correlation (3Y) Calculated over the trailing 3-year period	0.15
Correlation (5Y) Calculated over the trailing 5-year period	0.20
Correlation (All Time) Calculated using the full available price history since Jan 26, 2017	0.22

The correlation between APH and ANAB shifts across timeframes, from 0.09 (1 year) to 0.22 (all time), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap APH : $198.36B ANAB : $1.61B
EPS APH : $4.58 ANAB : -$0.91
PS Ratio APH : 7.62 ANAB : 7.11
PB Ratio APH : 14.19 ANAB : 126.20
Total Revenue (TTM) APH : $25.90B ANAB : $232.39M
Gross Profit (TTM) APH : $9.67B ANAB : $245.59M
EBITDA (TTM) APH : $7.45B ANAB : $52.72M

Return for Risk

APH vs. ANAB — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

APH

APH Risk / Return Rank: 80
APH Sharpe Ratio Rank: 84
APH Sortino Ratio Rank: 77
APH Omega Ratio Rank: 79
APH Calmar Ratio Rank: 79
APH Martin Ratio Rank: 80

ANAB

ANAB Risk / Return Rank: 96
ANAB Sharpe Ratio Rank: 98
ANAB Sortino Ratio Rank: 95
ANAB Omega Ratio Rank: 95
ANAB Calmar Ratio Rank: 97
ANAB Martin Ratio Rank: 97

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

APH vs. ANAB - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Amphenol Corporation (APH) and AnaptysBio, Inc. (ANAB). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	APH	ANAB	Difference
Sharpe ratio: Return per unit of total volatility	1.54	3.80	-2.26
Sortino ratio: Return per unit of downside risk	1.98	3.97	-1.99
Omega ratio: Gain probability vs. loss probability	1.28	1.53	-0.26
Calmar ratio: Return relative to maximum drawdown	2.27	9.28	-7.00
Martin ratio: Return relative to average drawdown	5.85	22.38	-16.52

APH vs. ANAB - Sharpe Ratio Comparison

The current APH Sharpe Ratio is 1.54, which is lower than the ANAB Sharpe Ratio of 3.80. The chart below compares the historical Sharpe Ratios of APH and ANAB, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

APH vs. ANAB - Drawdown Comparison

The maximum APH drawdown since its inception was -63.41%, smaller than the maximum ANAB drawdown of -92.08%. Use the drawdown chart below to compare losses from any high point for APH and ANAB.

Drawdown Indicators

	APH	ANAB	Difference
Max Drawdown Largest peak-to-trough decline	-63.41%	-92.08%	+28.67%
Max Drawdown (1Y) Largest decline over 1 year	-28.19%	-28.15%	-0.04%
Max Drawdown (3Y) Largest decline over 3 years	-28.19%	-69.32%	+41.13%
Max Drawdown (5Y) Largest decline over 5 years	-28.73%	-69.32%	+40.59%
Max Drawdown (10Y) Largest decline over 10 years	-37.56%	—	—
Current Drawdown Current decline from peak	-7.31%	-34.57%	+27.26%
Average Drawdown Average peak-to-trough decline	-13.56%	-64.64%	+51.08%
Ulcer Index Depth and duration of drawdowns from previous peaks	10.92%	11.64%	-0.72%

Volatility

APH vs. ANAB - Volatility Comparison

Amphenol Corporation (APH) has a higher volatility of 15.50% compared to AnaptysBio, Inc. (ANAB) at 12.40%. This indicates that APH's price experiences larger fluctuations and is considered to be riskier than ANAB based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	APH	ANAB	Difference
Volatility (1M) Calculated over the trailing 1-month period	15.50%	12.40%	+3.10%
Volatility (6M) Calculated over the trailing 6-month period	37.39%	46.31%	-8.92%
Volatility (1Y) Calculated over the trailing 1-year period	41.68%	68.78%	-27.10%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	30.75%	65.31%	-34.56%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	27.93%	75.44%	-47.51%

Dividends

APH vs. ANAB - Dividend Comparison

APH's dividend yield for the trailing twelve months is around 0.54%, while ANAB has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ANAB AnaptysBio, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
APH Amphenol Corporation	0.54%	0.55%	0.79%	1.07%	1.06%	0.89%	0.80%	0.89%	1.09%	0.80%	0.86%	1.01%

Financials

Frequently Asked Questions

Can I hold both APH and ANAB in my portfolio?

APH and ANAB have a correlation of 0.09, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, APH or ANAB?

APH has higher volatility (15.50%) compared to ANAB (12.40%). In terms of maximum drawdown, APH dropped -63.41% vs ANAB's -92.08%.

Which has better risk-adjusted returns?

ANAB currently has the higher Sharpe Ratio (3.80 vs 1.54), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.