VRTX vs. CRWD
VRTX (Vertex Pharmaceuticals Incorporated) and CRWD (CrowdStrike Holdings, Inc.) are both stocks. VRTX operates in Biotechnology (Healthcare), while CRWD operates in Software - Infrastructure (Technology). Over the past 5 years, VRTX returned 18.80%/yr vs 24.66%/yr for CRWD. Their 0.22 correlation means their historical movements had little consistent relationship.
Performance
VRTX vs. CRWD - Performance Comparison
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Returns By Period
In the year-to-date period, VRTX achieves a 5.24% return, which is significantly lower than CRWD's 62.86% return.
VRTX
- 1D
- -0.95%
- 1M
- -9.65%
- 6M
- 1.53%
- YTD
- 5.24%
- 1Y
- 3.24%
- 3Y*
- 11.12%
- 5Y*
- 18.80%
- 10Y*
- 17.01%
- ALL TIME*
- 14.20%
CRWD
- 1D
- 3.05%
- 1M
- -1.61%
- 6M
- 72.96%
- YTD
- 62.86%
- 1Y
- 70.92%
- 3Y*
- 66.31%
- 5Y*
- 24.66%
- 10Y*
- —
- ALL TIME*
- 41.70%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $1.40B | $1.60B | $2.05B | |
| $626.02M | $723.46M | $724.71M |
VRTX vs. CRWD - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|---|
VRTX Vertex Pharmaceuticals Incorporated | 5.24% | 12.58% | -1.03% | 40.90% | 31.50% | -7.08% | 7.94% | 27.30% |
CRWD CrowdStrike Holdings, Inc. | 62.86% | 37.00% | 34.01% | 142.49% | -48.58% | -3.34% | 324.74% | -21.46% |
Correlation
The correlation between VRTX and CRWD is 0.12, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.12 |
Correlation (3Y) Balances recent behavior with more history. | 0.14 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.19 |
Correlation (All Time) Calculated using the full available price history since Jun 12, 2019 | 0.22 |
Fundamentals
VRTX:
$121.09B
CRWD:
$194.34B
VRTX:
$16.90
CRWD:
-$0.02
VRTX:
9.99
CRWD:
9.58
VRTX:
4.62
CRWD:
10.62
VRTX:
$12.26B
CRWD:
$5.09B
VRTX:
$10.57B
CRWD:
$3.82B
VRTX:
$5.19B
CRWD:
$246.78M
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Return for Risk
VRTX vs. CRWD — Risk / Return Rank
VRTX
CRWD
VRTX vs. CRWD - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Vertex Pharmaceuticals Incorporated (VRTX) and CrowdStrike Holdings, Inc. (CRWD). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| VRTX | CRWD | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.30 | ||
| Sortino ratioReturn per unit of downside risk | -1.65 | ||
| Omega ratioGain probability vs. loss probability | 1.06 | 1.26 | -0.20 |
| Calmar ratioReturn relative to maximum drawdown | 0.20 | 1.84 | -1.64 |
| Martin ratioReturn relative to average drawdown | 0.40 | 4.40 | -3.99 |
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Drawdowns
VRTX vs. CRWD - Drawdown Comparison
The maximum VRTX drawdown since its inception was -91.77%, which is greater than CRWD's maximum drawdown of -67.69%. Use the drawdown chart below to compare losses from any high point for VRTX and CRWD.
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Drawdown Indicators
| VRTX | CRWD | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -91.77% | -67.69% | -24.08% |
Max Drawdown (1Y)Largest decline over 1 year | -22.39% | -37.18% | +14.79% |
Max Drawdown (3Y)Largest decline over 3 years | -29.07% | -44.44% | +15.37% |
Max Drawdown (5Y)Largest decline over 5 years | -29.07% | -67.69% | +38.62% |
Max Drawdown (10Y)Largest decline over 10 years | -41.60% | — | — |
Current DrawdownCurrent decline from peak | -9.91% | -9.43% | -0.48% |
Average DrawdownAverage peak-to-trough decline | -37.62% | -23.33% | -14.29% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 10.97% | 15.49% | -4.52% |
Volatility
VRTX vs. CRWD - Volatility Comparison
The current volatility for Vertex Pharmaceuticals Incorporated (VRTX) is 9.31%, while CrowdStrike Holdings, Inc. (CRWD) has a volatility of 16.39%. This indicates that VRTX experiences smaller price fluctuations and is considered to be less risky than CRWD based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| VRTX | CRWD | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 9.31% | 16.39% | -7.08% |
Volatility (6M)Calculated over the trailing 6-month period | 21.34% | 39.70% | -18.36% |
Volatility (1Y)Calculated over the trailing 1-year period | 34.90% | 47.78% | -12.88% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 28.77% | 51.09% | -22.32% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 32.72% | 55.97% | -23.25% |
Dividends
VRTX vs. CRWD - Dividend Comparison
Neither VRTX nor CRWD has paid dividends to shareholders.
Financials
VRTX vs. CRWD - Financials Comparison
This section allows you to compare key financial metrics between Vertex Pharmaceuticals Incorporated and CrowdStrike Holdings, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
VRTX vs. CRWD - Profitability Comparison
VRTX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Vertex Pharmaceuticals Incorporated reported a gross profit of 2.59B and revenue of 2.99B. Therefore, the gross margin over that period was 86.9%.
CRWD - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, CrowdStrike Holdings, Inc. reported a gross profit of 1.04B and revenue of 1.39B. Therefore, the gross margin over that period was 75.3%.
VRTX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Vertex Pharmaceuticals Incorporated reported an operating income of 1.14B and revenue of 2.99B, resulting in an operating margin of 38.1%.
CRWD - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, CrowdStrike Holdings, Inc. reported an operating income of -30.60M and revenue of 1.39B, resulting in an operating margin of -2.2%.
VRTX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Vertex Pharmaceuticals Incorporated reported a net income of 1.03B and revenue of 2.99B, resulting in a net margin of 34.5%.
CRWD - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, CrowdStrike Holdings, Inc. reported a net income of 45.97M and revenue of 1.39B, resulting in a net margin of 3.3%.
Frequently Asked Questions
VRTX and CRWD have a correlation of 0.12, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
CRWD has higher volatility (16.39%) compared to VRTX (9.31%). In terms of maximum drawdown, VRTX dropped -91.77% vs CRWD's -67.69%.
CRWD currently has the higher Sharpe Ratio (1.43 vs 0.13), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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