Direxion Daily Pharmaceutical & Medical Bull 3X Shares (PILL) Alternatives
Direxion Daily Pharmaceutical & Medical Bull 3X Shares (PILL) belongs to the Leveraged Equities category. Below you'll find alternative ETFs from the same category, ranked by key criteria, plus funds that investors commonly compare with PILL. Use the tables to find lower-cost options, better risk-adjusted returns, or funds that fit a different role in your portfolio.
Cheapest Alternatives to PILL
PILL charges 0.98% annually. Among ETFs in the Leveraged Equities category, these options have the lowest expense ratios among PILL alternatives.
| Symbol | Name | Expense Ratio | Inception | |
|---|---|---|---|---|
| ETRACS IFED Invest with the Fed TR Index ETN | 0.45% | Sep 14, 2021 | PILL vs IFED | |
| Direxion Daily S&P 500 Bull 2x Shares | 0.64% | May 28, 2014 | PILL vs SPUU | |
| Leverage Shares 2X Long NVDA Daily ETF | 0.75% | Dec 12, 2024 | PILL vs NVDG | |
| Leverage Shares 2X Long AMD Daily ETF | 0.75% | Jan 24, 2025 | PILL vs AMDG | |
| Leverage Shares 2X Long TSLA Daily ETF | 0.75% | Dec 12, 2024 | PILL vs TSLG |
Best Risk-Adjusted Alternatives to PILL
Among ETFs in the Leveraged Equities category, these options rank highest on PortfoliosLab's risk-adjusted score, which accounts for volatility, drawdown, and return consistency over a 1-year period.
| Symbol | Name | Risk / Return Rank | Inception | |
|---|---|---|---|---|
| Direxion Daily South Korea Bull 3X Shares | 98 | Apr 10, 2013 | PILL vs KORU | |
| Direxion Daily MU Bull 2X Shares | 98 | Oct 9, 2024 | PILL vs MUU | |
| GraniteShares 2x Long MU Daily ETF | 98 | Nov 11, 2024 | PILL vs MULL | |
| Direxion Daily GOOGL Bull 2X Shares | 96 | Sep 6, 2022 | PILL vs GGLL | |
| Direxion Daily TSM Bull 2X Shares | 96 | Oct 3, 2024 | PILL vs TSMX |
Top Performing PILL Alternatives (YTD)
PILL alternatives from the Leveraged Equities category, sorted by year-to-date return.
| Symbol | Name | YTD Return | Inception | |
|---|---|---|---|---|
| MicroSectors U.S. Big Oil Index 3X Leveraged ETN | 168.34% | Apr 9, 2019 | PILL vs NRGU | |
| MicroSectors Energy 3X Leveraged ETN | 141.86% | Feb 16, 2023 | PILL vs WTIU | |
| Leverage Shares 2X Long TER Daily ETF | 102.79% | Nov 17, 2025 | PILL vs TERG | |
| Direxion Daily S&P Oil & Gas Exploration & Product... | 102.61% | Apr 1, 2020 | PILL vs GUSH | |
| ProShares Ultra Oil & Gas | 85.56% | Jan 30, 2007 | PILL vs DIG |
Lowest Volatility Alternatives to PILL
PILL alternatives from the Leveraged Equities category, sorted by annualized volatility over the past year.
| Symbol | Name | Volatility 1Y | Inception | |
|---|---|---|---|---|
| Innovator U.S. Equity Accelerated Plus ETF | 14.33% | Apr 1, 2021 | PILL vs XTAP | |
| Innovator Growth Accelerated Plus ETF - April | 16.31% | Apr 1, 2021 | PILL vs QTAP | |
| Roundhill BRKB WeeklyPay ETF | 17.95% | Jun 17, 2025 | PILL vs BRKW | |
| Innovator US Equity Accelerated ETF | 17.99% | Apr 1, 2021 | PILL vs XDSQ | |
| Innovator U.S. Equity Accelerated Plus ETF - July | 18.18% | Jul 1, 2021 | PILL vs XTJL |
Lowest Drawdown Alternatives to PILL
PILL alternatives from the Leveraged Equities category, sorted by maximum drawdown over the past year.
| Symbol | Name | Max Drawdown 1Y | Inception | |
|---|---|---|---|---|
| Innovator U.S. Equity Accelerated Plus ETF | -11.83% | Apr 1, 2021 | PILL vs XTAP | |
| Innovator Growth Accelerated Plus ETF - April | -12.04% | Apr 1, 2021 | PILL vs QTAP | |
| Innovator US Equity Accelerated ETF | -12.18% | Apr 1, 2021 | PILL vs XDSQ | |
| Innovator Growth Accelerated ETF - Quarterly | -12.64% | Apr 1, 2021 | PILL vs XDQQ | |
| Innovator U.S. Equity Accelerated Plus ETF - July | -13.81% | Jul 1, 2021 | PILL vs XTJL |
Other ETFs from Direxion
Most popular Direxion ETFs on PortfoliosLab, across asset classes.
Often Compared With PILL
What investors most often compare with PILL, based on PortfoliosLab usage data.
Compare PILL with Any Fund or Stock
Compare PILL with any ETF, mutual fund, or stock using PortfoliosLab's comparison tool.