PILL vs. LABU
Compare and contrast key facts about Direxion Daily Pharmaceutical & Medical Bull 3X Shares (PILL) and Direxion Daily S&P Biotech Bull 3x Shares (LABU).
PILL and LABU are both exchange-traded funds (ETFs), meaning they are traded on stock exchanges and can be bought and sold throughout the day. PILL is a passively managed fund by Direxion that tracks the performance of the Dynamic Pharmaceuticals Intellidex Index. It was launched on Nov 15, 2017. LABU is a passively managed fund by Direxion that tracks the performance of the S&P Biotechnology Select Industry Index (300%). It was launched on May 28, 2015. Both PILL and LABU are passive ETFs, meaning that they are not actively managed but aim to replicate the performance of the underlying index as closely as possible.
Performance
PILL vs. LABU - Performance Comparison
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PILL vs. LABU - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
PILL Direxion Daily Pharmaceutical & Medical Bull 3X Shares | -13.41% | 75.14% | -7.26% | -12.06% | -43.16% | -37.33% | 0.28% | 19.26% | -21.15% | 16.39% |
LABU Direxion Daily S&P Biotech Bull 3x Shares | 6.42% | 79.17% | -26.02% | -13.41% | -80.36% | -64.15% | 74.66% | 75.50% | -57.61% | 16.89% |
Returns By Period
In the year-to-date period, PILL achieves a -13.41% return, which is significantly lower than LABU's 6.42% return.
PILL
- 1D
- 4.11%
- 1M
- -16.66%
- YTD
- -13.41%
- 6M
- 28.03%
- 1Y
- 69.42%
- 3Y*
- 8.95%
- 5Y*
- -12.72%
- 10Y*
- —
LABU
- 1D
- 2.13%
- 1M
- 0.08%
- YTD
- 6.42%
- 6M
- 75.49%
- 1Y
- 215.44%
- 3Y*
- 20.71%
- 5Y*
- -36.11%
- 10Y*
- -11.62%
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PILL vs. LABU - Expense Ratio Comparison
PILL has a 0.98% expense ratio, which is lower than LABU's 1.12% expense ratio.
Return for Risk
PILL vs. LABU — Risk / Return Rank
PILL
LABU
PILL vs. LABU - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Direxion Daily Pharmaceutical & Medical Bull 3X Shares (PILL) and Direxion Daily S&P Biotech Bull 3x Shares (LABU). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| PILL | LABU | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 1.02 | 2.53 | -1.51 |
Sortino ratioReturn per unit of downside risk | 1.63 | 2.77 | -1.14 |
Omega ratioGain probability vs. loss probability | 1.20 | 1.35 | -0.15 |
Calmar ratioReturn relative to maximum drawdown | 1.34 | 4.94 | -3.60 |
Martin ratioReturn relative to average drawdown | 3.67 | 15.35 | -11.68 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| PILL | LABU | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.02 | 2.53 | -1.51 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.21 | -0.38 | +0.16 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | -0.12 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.13 | -0.24 | +0.11 |
Correlation
The correlation between PILL and LABU is 0.77, which is considered to be high. That indicates a strong positive relationship between their price movements. Having highly-correlated positions in a portfolio may signal a lack of diversification, potentially leading to increased risk during market downturns.
Dividends
PILL vs. LABU - Dividend Comparison
PILL's dividend yield for the trailing twelve months is around 0.72%, less than LABU's 0.73% yield.
| TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
PILL Direxion Daily Pharmaceutical & Medical Bull 3X Shares | 0.72% | 0.69% | 1.28% | 1.83% | 0.67% | 0.00% | 0.00% | 0.38% | 0.91% | 0.10% |
LABU Direxion Daily S&P Biotech Bull 3x Shares | 0.73% | 0.84% | 0.35% | 0.35% | 0.00% | 0.00% | 0.00% | 0.28% | 0.64% | 0.17% |
Drawdowns
PILL vs. LABU - Drawdown Comparison
The maximum PILL drawdown since its inception was -88.76%, smaller than the maximum LABU drawdown of -99.18%. Use the drawdown chart below to compare losses from any high point for PILL and LABU.
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Drawdown Indicators
| PILL | LABU | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -88.76% | -99.18% | +10.42% |
Max Drawdown (1Y)Largest decline over 1 year | -36.51% | -36.66% | +0.15% |
Max Drawdown (5Y)Largest decline over 5 years | -83.38% | -97.75% | +14.37% |
Max Drawdown (10Y)Largest decline over 10 years | — | -98.96% | — |
Current DrawdownCurrent decline from peak | -70.33% | -96.25% | +25.92% |
Average DrawdownAverage peak-to-trough decline | -58.39% | -81.45% | +23.06% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 13.31% | 11.80% | +1.51% |
Volatility
PILL vs. LABU - Volatility Comparison
The current volatility for Direxion Daily Pharmaceutical & Medical Bull 3X Shares (PILL) is 26.05%, while Direxion Daily S&P Biotech Bull 3x Shares (LABU) has a volatility of 33.08%. This indicates that PILL experiences smaller price fluctuations and is considered to be less risky than LABU based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| PILL | LABU | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 26.05% | 33.08% | -7.03% |
Volatility (6M)Calculated over the trailing 6-month period | 46.70% | 56.88% | -10.18% |
Volatility (1Y)Calculated over the trailing 1-year period | 69.59% | 86.51% | -16.92% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 59.66% | 95.74% | -36.08% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 63.76% | 95.89% | -32.13% |