XDNA.TO vs. TDOC.TO
XDNA.TO (iShares Genomics Immunology and Healthcare Index ETF) and TDOC.TO (TD Global Healthcare Leaders Index ETF) are both Health & Biotech Equities funds. XDNA.TO is passively managed, while TDOC.TO is actively managed. Over the past 3 years, XDNA.TO returned 14.14%/yr vs 7.42%/yr for TDOC.TO. At a 0.22 correlation, their price movements are largely independent.
Performance
XDNA.TO vs. TDOC.TO - Performance Comparison
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Returns By Period
In the year-to-date period, XDNA.TO achieves a 28.27% return, which is significantly higher than TDOC.TO's 1.90% return.
XDNA.TO
- 1D
- -0.71%
- 1M
- 10.45%
- 6M
- 16.34%
- YTD
- 28.27%
- 1Y
- 59.77%
- 3Y*
- 14.14%
- 5Y*
- —
- 10Y*
- —
TDOC.TO
- 1D
- 1.32%
- 1M
- 5.07%
- 6M
- -1.74%
- YTD
- 1.90%
- 1Y
- 13.79%
- 3Y*
- 7.42%
- 5Y*
- 5.37%
- 10Y*
- —
XDNA.TO vs. TDOC.TO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
XDNA.TO iShares Genomics Immunology and Healthcare Index ETF | 28.27% | 12.10% | 5.54% | -7.84% | -14.85% |
TDOC.TO TD Global Healthcare Leaders Index ETF | 1.90% | 8.36% | 10.24% | 1.71% | 7.65% |
Correlation
The correlation between XDNA.TO and TDOC.TO is 0.29, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.29 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.23 |
Correlation (All Time) Calculated using the full available price history since May 4, 2022 | 0.22 |
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Return for Risk
XDNA.TO vs. TDOC.TO — Risk / Return Rank
XDNA.TO
TDOC.TO
XDNA.TO vs. TDOC.TO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares Genomics Immunology and Healthcare Index ETF (XDNA.TO) and TD Global Healthcare Leaders Index ETF (TDOC.TO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| XDNA.TO | TDOC.TO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.37 | ||
| Sortino ratioReturn per unit of downside risk | +1.68 | ||
| Omega ratioGain probability vs. loss probability | 1.39 | 1.18 | +0.22 |
| Calmar ratioReturn relative to maximum drawdown | 6.95 | 1.18 | +5.78 |
| Martin ratioReturn relative to average drawdown | 15.82 | 2.79 | +13.03 |
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Drawdowns
XDNA.TO vs. TDOC.TO - Drawdown Comparison
The maximum XDNA.TO drawdown since its inception was -45.90%, which is greater than TDOC.TO's maximum drawdown of -17.52%. Use the drawdown chart below to compare losses from any high point for XDNA.TO and TDOC.TO.
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Drawdown Indicators
| XDNA.TO | TDOC.TO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -45.90% | -17.52% | -28.38% |
Max Drawdown (1Y)Largest decline over 1 year | -8.64% | -11.77% | +3.13% |
Max Drawdown (3Y)Largest decline over 3 years | -28.29% | -12.66% | -15.63% |
Max Drawdown (5Y)Largest decline over 5 years | — | -17.52% | — |
Current DrawdownCurrent decline from peak | -7.51% | -3.35% | -4.16% |
Average DrawdownAverage peak-to-trough decline | -22.98% | -4.82% | -18.16% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 3.79% | 4.95% | -1.16% |
Volatility
XDNA.TO vs. TDOC.TO - Volatility Comparison
iShares Genomics Immunology and Healthcare Index ETF (XDNA.TO) has a higher volatility of 7.90% compared to TD Global Healthcare Leaders Index ETF (TDOC.TO) at 5.21%. This indicates that XDNA.TO's price experiences larger fluctuations and is considered to be riskier than TDOC.TO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| XDNA.TO | TDOC.TO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 7.90% | 5.21% | +2.69% |
Volatility (6M)Calculated over the trailing 6-month period | 18.84% | 10.81% | +8.03% |
Volatility (1Y)Calculated over the trailing 1-year period | 25.66% | 14.25% | +11.41% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 25.41% | 13.08% | +12.33% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 25.41% | 12.94% | +12.47% |
Dividends
XDNA.TO vs. TDOC.TO - Dividend Comparison
XDNA.TO's dividend yield for the trailing twelve months is around 0.25%, less than TDOC.TO's 1.17% yield.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
TDOC.TO TD Global Healthcare Leaders Index ETF | 1.17% | 1.09% | 3.68% | 0.98% | 1.16% | 0.60% |
XDNA.TO iShares Genomics Immunology and Healthcare Index ETF | 0.25% | 0.43% | 0.32% | 0.25% | 0.32% | 0.00% |
Frequently Asked Questions
XDNA.TO and TDOC.TO have a correlation of 0.29, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
They also come from different issuers: iShares and TD.
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