XDNA.TO vs. FBTU.L
XDNA.TO (iShares Genomics Immunology and Healthcare Index ETF) and FBTU.L (First Trust NYSE Arca Biotechnology UCITS ETF Class A USD Accumulating) are both Health & Biotech Equities funds. Over the past 3 years, XDNA.TO returned 16.93%/yr vs 20.54%/yr for FBTU.L. At a 0.33 correlation, their price movements are largely independent. XDNA.TO charges 0.44%/yr vs 0.60%/yr for FBTU.L.
Performance
XDNA.TO vs. FBTU.L - Performance Comparison
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Different Trading Currencies
XDNA.TO is traded in CAD, while FBTU.L is traded in USD. To make them comparable, the FBTU.L values have been converted to CAD using the latest available exchange rates.
Returns By Period
In the year-to-date period, XDNA.TO achieves a 33.92% return, which is significantly higher than FBTU.L's 23.16% return.
XDNA.TO
- 1D
- 0.61%
- 1M
- 16.88%
- YTD
- 33.92%
- 6M
- 32.78%
- 1Y
- 71.75%
- 3Y*
- 16.93%
- 5Y*
- —
- 10Y*
- —
FBTU.L
- 1D
- 1.06%
- 1M
- 15.57%
- YTD
- 23.16%
- 6M
- 22.52%
- 1Y
- 60.01%
- 3Y*
- 20.54%
- 5Y*
- 10.64%
- 10Y*
- —
XDNA.TO vs. FBTU.L - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
XDNA.TO iShares Genomics Immunology and Healthcare Index ETF | 33.92% | 12.10% | 5.54% | -7.84% | -14.85% |
FBTU.L First Trust NYSE Arca Biotechnology UCITS ETF Class A USD Accumulating | 23.16% | 20.22% | 13.60% | 1.44% | 15.17% |
Correlation
The correlation between XDNA.TO and FBTU.L is 0.45, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.45 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.36 |
Correlation (All Time) Calculated using the full available price history since May 4, 2022 | 0.33 |
The correlation between XDNA.TO and FBTU.L shifts across timeframes, from 0.33 (all time) to 0.45 (1 year), reflecting how their relationship changes across market environments.
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Return for Risk
XDNA.TO vs. FBTU.L — Risk / Return Rank
XDNA.TO
FBTU.L
XDNA.TO vs. FBTU.L - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares Genomics Immunology and Healthcare Index ETF (XDNA.TO) and First Trust NYSE Arca Biotechnology UCITS ETF Class A USD Accumulating (FBTU.L). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| XDNA.TO | FBTU.L | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.12 | ||
| Sortino ratioReturn per unit of downside risk | -0.06 | ||
| Omega ratioGain probability vs. loss probability | 1.47 | 1.45 | +0.03 |
| Calmar ratioReturn relative to maximum drawdown | 8.35 | 3.89 | +4.46 |
| Martin ratioReturn relative to average drawdown | 19.59 | 10.29 | +9.30 |
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Drawdowns
XDNA.TO vs. FBTU.L - Drawdown Comparison
The maximum XDNA.TO drawdown since its inception was -45.90%, which is greater than FBTU.L's maximum drawdown of -36.00%. Use the drawdown chart below to compare losses from any high point for XDNA.TO and FBTU.L.
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Drawdown Indicators
| XDNA.TO | FBTU.L | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -45.90% | -36.00% | -9.90% |
Max Drawdown (1Y)Largest decline over 1 year | -8.64% | -15.35% | +6.71% |
Max Drawdown (3Y)Largest decline over 3 years | -28.29% | -23.76% | -4.53% |
Max Drawdown (5Y)Largest decline over 5 years | — | -29.17% | — |
Current DrawdownCurrent decline from peak | 0.00% | 0.00% | 0.00% |
Average DrawdownAverage peak-to-trough decline | -23.18% | -13.95% | -9.23% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 3.67% | 5.82% | -2.15% |
Volatility
XDNA.TO vs. FBTU.L - Volatility Comparison
iShares Genomics Immunology and Healthcare Index ETF (XDNA.TO) and First Trust NYSE Arca Biotechnology UCITS ETF Class A USD Accumulating (FBTU.L) have volatilities of 7.64% and 7.64%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| XDNA.TO | FBTU.L | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 7.64% | 7.64% | 0.00% |
Volatility (6M)Calculated over the trailing 6-month period | 18.67% | 17.04% | +1.63% |
Volatility (1Y)Calculated over the trailing 1-year period | 25.18% | 21.76% | +3.42% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 25.36% | 21.06% | +4.30% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 25.36% | 21.46% | +3.90% |
XDNA.TO vs. FBTU.L - Expense Ratio Comparison
XDNA.TO has a 0.44% expense ratio, which is lower than FBTU.L's 0.60% expense ratio.
Dividends
XDNA.TO vs. FBTU.L - Dividend Comparison
XDNA.TO's dividend yield for the trailing twelve months is around 0.24%, while FBTU.L has not paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
FBTU.L First Trust NYSE Arca Biotechnology UCITS ETF Class A USD Accumulating | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
XDNA.TO iShares Genomics Immunology and Healthcare Index ETF | 0.24% | 0.43% | 0.32% | 0.25% | 0.32% |
Frequently Asked Questions
XDNA.TO and FBTU.L have a correlation of 0.45, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, XDNA.TO is cheaper at 0.44% per year. The better choice depends on whether you care most about return, fees, risk, or income.
XDNA.TO is cheaper with a 0.44% expense ratio, compared with 0.60% for FBTU.L.
They also come from different issuers: iShares and First Trust. Their fees differ too: 0.44% for XDNA.TO and 0.60% for FBTU.L.
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