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QURE vs. CNTA
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

QURE vs. CNTA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in uniQure N.V. (QURE) and Centessa Pharmaceuticals Limited (CNTA). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, QURE achieves a 12.83% return, which is significantly lower than CNTA's 58.74% return.


QURE

1D
2.08%
1M
-2.39%
YTD
12.83%
6M
24.02%
1Y
56.34%
3Y*
11.25%
5Y*
-5.87%
10Y*
8.62%

CNTA

1D
0.20%
1M
0.28%
YTD
58.74%
6M
34.58%
1Y
233.05%
3Y*
104.97%
5Y*
12.71%
10Y*
*Multi-year figures are annualized to reflect compound growth (CAGR)

QURE vs. CNTA - Yearly Performance Comparison


2026 (YTD)20252024202320222021
QURE
uniQure N.V.
12.83%35.50%160.86%-70.14%9.31%-40.28%
CNTA
Centessa Pharmaceuticals Limited
58.74%49.31%110.43%156.77%-72.47%-48.23%

Correlation

The correlation between QURE and CNTA is 0.16, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.16

Correlation (3Y)
Calculated over the trailing 3-year period

0.23

Correlation (5Y)
Calculated over the trailing 5-year period

0.25

Correlation (All Time)
Calculated using the full available price history since Jun 1, 2021

0.24

Fundamentals

EPS

QURE:

-$3.58

CNTA:

-$1.81

PS Ratio

QURE:

87.14

CNTA:

354.44

Total Revenue (TTM)

QURE:

$18.09M

CNTA:

$15.00M

Gross Profit (TTM)

QURE:

$13.42M

CNTA:

$15.00M

EBITDA (TTM)

QURE:

-$164.53M

CNTA:

-$227.27M

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Return for Risk

QURE vs. CNTA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

QURE
QURE Risk / Return Rank: 6868
Overall Rank
QURE Sharpe Ratio Rank: 5050
Sharpe Ratio Rank
QURE Sortino Ratio Rank: 8888
Sortino Ratio Rank
QURE Omega Ratio Rank: 9090
Omega Ratio Rank
QURE Calmar Ratio Rank: 5757
Calmar Ratio Rank
QURE Martin Ratio Rank: 5454
Martin Ratio Rank

CNTA
CNTA Risk / Return Rank: 9797
Overall Rank
CNTA Sharpe Ratio Rank: 9797
Sharpe Ratio Rank
CNTA Sortino Ratio Rank: 9898
Sortino Ratio Rank
CNTA Omega Ratio Rank: 9797
Omega Ratio Rank
CNTA Calmar Ratio Rank: 9797
Calmar Ratio Rank
CNTA Martin Ratio Rank: 9797
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

QURE vs. CNTA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for uniQure N.V. (QURE) and Centessa Pharmaceuticals Limited (CNTA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


QURECNTADifference
Sharpe ratioReturn per unit of total volatility

-3.33

Sortino ratioReturn per unit of downside risk

-2.47

Omega ratioGain probability vs. loss probability

1.43

1.69

-0.27

Calmar ratioReturn relative to maximum drawdown

0.65

8.90

-8.25

Martin ratioReturn relative to average drawdown

1.06

24.63

-23.57

QURE vs. CNTA - Sharpe Ratio Comparison

The current QURE Sharpe Ratio is 0.21, which is lower than the CNTA Sharpe Ratio of 3.54. The chart below compares the historical Sharpe Ratios of QURE and CNTA, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Sharpe Ratios by Period


QURECNTADifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

0.21

3.54

-3.33

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

-0.04

0.18

-0.22

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

0.07

Sharpe Ratio (All Time)

Calculated using the full available price history

0.05

0.18

-0.13

Drawdowns

QURE vs. CNTA - Drawdown Comparison

The maximum QURE drawdown since its inception was -95.40%, which is greater than CNTA's maximum drawdown of -88.19%. Use the drawdown chart below to compare losses from any high point for QURE and CNTA.


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Drawdown Indicators


QURECNTADifference

Max Drawdown

Largest peak-to-trough decline

-95.40%

-88.19%

-7.21%

Max Drawdown (1Y)

Largest decline over 1 year

-87.21%

-26.38%

-60.83%

Max Drawdown (3Y)

Largest decline over 3 years

-87.21%

-43.72%

-43.49%

Max Drawdown (5Y)

Largest decline over 5 years

-90.11%

-88.19%

-1.92%

Max Drawdown (10Y)

Largest decline over 10 years

-95.40%

Current Drawdown

Current decline from peak

-67.15%

-0.50%

-66.65%

Average Drawdown

Average peak-to-trough decline

-56.58%

-51.99%

-4.59%

Ulcer Index

Depth and duration of drawdowns from previous peaks

53.50%

9.51%

+43.99%

Volatility

QURE vs. CNTA - Volatility Comparison

uniQure N.V. (QURE) has a higher volatility of 28.01% compared to Centessa Pharmaceuticals Limited (CNTA) at 0.72%. This indicates that QURE's price experiences larger fluctuations and is considered to be riskier than CNTA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


QURECNTADifference

Volatility (1M)

Calculated over the trailing 1-month period

28.01%

0.72%

+27.29%

Volatility (6M)

Calculated over the trailing 6-month period

92.44%

44.27%

+48.17%

Volatility (1Y)

Calculated over the trailing 1-year period

273.61%

66.48%

+207.13%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

154.08%

72.09%

+81.99%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

119.92%

72.30%

+47.62%

Dividends

QURE vs. CNTA - Dividend Comparison

Neither QURE nor CNTA has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

QURE vs. CNTA - Financials Comparison

This section allows you to compare key financial metrics between uniQure N.V. and Centessa Pharmaceuticals Limited. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.00100.00M200.00M300.00M400.00M500.00M20222023202420252026
3.56M
0
(QURE) Total Revenue
(CNTA) Total Revenue
Values in USD except per share items

Frequently Asked Questions


QURE and CNTA have a correlation of 0.16, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

QURE has higher volatility (28.01%) compared to CNTA (0.72%). In terms of maximum drawdown, QURE dropped -95.40% vs CNTA's -88.19%.

CNTA currently has the higher Sharpe Ratio (3.54 vs 0.21), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for QURE and CNTA

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