Highlights
- Market Cap
- $940.16M
- Enterprise Value
- $927.17M
- EPS (TTM)
- -$3.49
- Total Revenue (TTM)
- $16.10M
- Gross Profit (TTM)
- $14.41M
- EBITDA (TTM)
- -$144.25M
- Year Range
- $7.76 - $71.50
- Target Price
- $47.22
- ROA (TTM)
- -24.12%
- ROE (TTM)
- -100.04%
Share Price Chart
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Performance
Performance Chart
The chart shows the growth of an initial investment of $10,000 in uniQure N.V., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.
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Returns By Period
uniQure N.V. (QURE) has returned -31.68% so far this year and 54.25% over the past 12 months. Over the last ten years, QURE has returned 2.52% per year, falling short of the S&P 500 Index benchmark, which averaged 12.16% annually.
uniQure N.V.
- 1D
- 11.00%
- 1M
- 4.61%
- YTD
- -31.68%
- 6M
- -71.99%
- 1Y
- 54.25%
- 3Y*
- -6.71%
- 5Y*
- -13.68%
- 10Y*
- 2.52%
Benchmark (S&P 500 Index)
- 1D
- 2.91%
- 1M
- -5.09%
- YTD
- -4.63%
- 6M
- -2.39%
- 1Y
- 16.33%
- 3Y*
- 16.69%
- 5Y*
- 10.18%
- 10Y*
- 12.16%
Monthly Returns
Based on dividend-adjusted daily data since Feb 5, 2014, QURE's average daily return is +0.19%, while the average monthly return is +3.66%. At this rate, your investment would double in approximately 1.6 years.
Historically, 42% of months were positive and 58% were negative. The best month was Sep 2025 with a return of +257.4%, while the worst month was Nov 2025 at -59.4%. The longest winning streak lasted 8 consecutive months, and the longest losing streak was 11 months.
On a daily basis, QURE closed higher 47% of trading days. The best single day was Sep 24, 2025 with a return of +247.7%, while the worst single day was Nov 3, 2025 at -49.3%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -5.06% | -31.21% | 4.61% | -31.68% | |||||||||
| 2025 | -10.87% | -16.45% | -19.39% | 39.25% | -1.96% | -3.66% | -0.14% | 17.31% | 257.44% | 15.97% | -59.36% | -13.01% | 35.50% |
| 2024 | -17.87% | 3.42% | -9.57% | -15.19% | 12.24% | -9.49% | 70.98% | -23.63% | -15.73% | 16.02% | 4.37% | 195.81% | 160.86% |
| 2023 | -6.26% | -1.36% | -3.91% | -3.62% | -0.62% | -40.59% | -9.51% | -16.01% | -22.96% | -15.05% | 18.95% | -0.15% | -70.14% |
| 2022 | -12.97% | -5.87% | 6.36% | -17.32% | -3.88% | 29.81% | 36.00% | -22.92% | -3.99% | -0.75% | 42.11% | -14.32% | 9.31% |
| 2021 | -1.99% | 3.64% | -8.20% | -4.21% | 7.62% | -11.32% | -5.81% | -0.03% | 10.38% | -4.81% | -8.60% | -25.53% | -42.60% |
Benchmark Metrics
uniQure N.V. has an annualized alpha of 38.46%, beta of 1.17, and R² of 0.03 versus S&P 500 Index. Calculated based on daily prices since February 06, 2014.
- This stock participated in 114.37% of S&P 500 Index downside but only 67.94% of its upside — more exposed to losses than it benefited from rallies.
- R² of 0.03 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- 38.46%
- Beta
- 1.17
- R²
- 0.03
- Upside Capture
- 67.94%
- Downside Capture
- 114.37%
Return for Risk
Risk / Return Rank
QURE ranks 65 for risk / return — better than 65% of stocks on our site. You're getting solid returns for the risk taken. A good sign, especially for investors who want growth without excessive volatility.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for uniQure N.V. (QURE) and compare them to a chosen benchmark (S&P 500 Index).
| QURE | Benchmark | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 0.20 | 0.90 | -0.70 |
Sortino ratioReturn per unit of downside risk | 2.80 | 1.39 | +1.42 |
Omega ratioGain probability vs. loss probability | 1.42 | 1.21 | +0.21 |
Calmar ratioReturn relative to maximum drawdown | 0.36 | 1.40 | -1.04 |
Martin ratioReturn relative to average drawdown | 0.70 | 6.61 | -5.91 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
Explore QURE risk-adjusted metrics in detail
Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the uniQure N.V.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the uniQure N.V. was 95.40%, occurring on Jul 8, 2024. The portfolio has not yet recovered.
The current uniQure N.V. drawdown is 80.11%.
Depth | Start | To Bottom | Bottom | To Recover | End | Total |
|---|---|---|---|---|---|---|
| -95.4% | Jun 24, 2019 | 1268 | Jul 8, 2024 | — | — | — |
| -85.67% | Apr 8, 2015 | 527 | May 9, 2017 | 263 | May 24, 2018 | 790 |
| -52.19% | Feb 27, 2014 | 59 | May 21, 2014 | 161 | Jan 9, 2015 | 220 |
| -47.08% | Sep 5, 2018 | 51 | Nov 14, 2018 | 67 | Feb 25, 2019 | 118 |
| -25.51% | Jun 21, 2018 | 27 | Jul 30, 2018 | 21 | Aug 28, 2018 | 48 |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of uniQure N.V. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how uniQure N.V. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PS Ratio
This chart shows the Price-to-Sales (P/S) ratio for QURE relative to other companies in the Biotechnology industry. Currently, QURE has a P/S ratio of 57.8. This P/S ratio is high relative to other companies in the industry. It could mean the stock is overvalued, or that investors expect strong future growth and profitability.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for QURE in comparison with other companies in the Biotechnology industry. Currently, QURE has a P/B value of 4.7. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.
Income Statement
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