MDGL vs. COST
MDGL (Madrigal Pharmaceuticals, Inc.) and COST (Costco Wholesale Corporation) are both stocks. MDGL operates in Biotechnology (Healthcare), while COST operates in Discount Stores (Consumer Defensive). Over the past 10 years, MDGL returned 52.15%/yr vs 21.10%/yr for COST. Their 0.18 correlation means their historical movements had little consistent relationship.
Performance
MDGL vs. COST - Performance Comparison
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Returns By Period
In the year-to-date period, MDGL achieves a -19.75% return, which is significantly lower than COST's 10.87% return. Over the past 10 years, MDGL has outperformed COST with an annualized return of 52.15%, while COST has yielded a comparatively lower 21.10% annualized return.
MDGL
- 1D
- -5.23%
- 1M
- -11.51%
- 6M
- -4.49%
- YTD
- -19.75%
- 1Y
- 54.65%
- 3Y*
- 32.19%
- 5Y*
- 39.86%
- 10Y*
- 52.15%
- ALL TIME*
- 1.50%
COST
- 1D
- -0.24%
- 1M
- 0.18%
- 6M
- 1.55%
- YTD
- 10.87%
- 1Y
- 0.52%
- 3Y*
- 21.34%
- 5Y*
- 18.51%
- 10Y*
- 21.10%
- ALL TIME*
- 16.98%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $1.83B | $2.11B | $2.34B | |
| $214.24M | $192.42M | $186.26M |
MDGL vs. COST - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
MDGL Madrigal Pharmaceuticals, Inc. | -19.75% | 88.72% | 33.36% | -20.28% | 242.52% | -23.77% | 22.02% | -19.17% | 22.80% | 516.04% |
COST Costco Wholesale Corporation | 10.87% | -5.39% | 39.62% | 49.00% | -19.05% | 51.82% | 32.67% | 45.70% | 10.60% | 22.37% |
Correlation
The correlation between MDGL and COST is -0.08, meaning there was essentially no consistent relationship between their historical price movements. Each responded to its own set of market drivers.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | -0.08 |
Correlation (3Y) Balances recent behavior with more history. | 0.12 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.14 |
Correlation (10Y) Provides a long-term view across more market conditions. | 0.15 |
Correlation (All Time) Calculated using the full available price history since Feb 6, 2007 | 0.18 |
The correlation between MDGL and COST shifts across timeframes, from -0.08 (1 year) to 0.18 (all time), reflecting how their relationship changes across market environments.
Fundamentals
MDGL:
$10.77B
COST:
$422.14B
MDGL:
-$12.61
COST:
$26.51
MDGL:
9.38
COST:
1.08
MDGL:
$1.28B
COST:
$293.59B
MDGL:
$1.17B
COST:
$11.12B
MDGL:
-$298.76M
COST:
$12.48B
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Return for Risk
MDGL vs. COST — Risk / Return Rank
MDGL
COST
MDGL vs. COST - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Madrigal Pharmaceuticals, Inc. (MDGL) and Costco Wholesale Corporation (COST). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| MDGL | COST | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.12 | ||
| Sortino ratioReturn per unit of downside risk | +1.63 | ||
| Omega ratioGain probability vs. loss probability | 1.24 | 1.03 | +0.21 |
| Calmar ratioReturn relative to maximum drawdown | 1.86 | 0.12 | +1.74 |
| Martin ratioReturn relative to average drawdown | 3.94 | 0.26 | +3.68 |
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Drawdowns
MDGL vs. COST - Drawdown Comparison
The maximum MDGL drawdown since its inception was -98.40%, which is greater than COST's maximum drawdown of -53.39%. Use the drawdown chart below to compare losses from any high point for MDGL and COST.
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Drawdown Indicators
| MDGL | COST | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -98.40% | -53.39% | -45.01% |
Max Drawdown (1Y)Largest decline over 1 year | -29.36% | -16.57% | -12.79% |
Max Drawdown (3Y)Largest decline over 3 years | -38.75% | -20.74% | -18.01% |
Max Drawdown (5Y)Largest decline over 5 years | -61.41% | -31.40% | -30.01% |
Max Drawdown (10Y)Largest decline over 10 years | -82.19% | -31.40% | -50.79% |
Current DrawdownCurrent decline from peak | -22.48% | -12.88% | -9.60% |
Average DrawdownAverage peak-to-trough decline | -58.21% | -13.36% | -44.85% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 13.86% | 7.81% | +6.05% |
Volatility
MDGL vs. COST - Volatility Comparison
Madrigal Pharmaceuticals, Inc. (MDGL) has a higher volatility of 15.14% compared to Costco Wholesale Corporation (COST) at 7.34%. This indicates that MDGL's price experiences larger fluctuations and is considered to be riskier than COST based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| MDGL | COST | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 15.14% | 7.34% | +7.80% |
Volatility (6M)Calculated over the trailing 6-month period | 32.24% | 15.13% | +17.11% |
Volatility (1Y)Calculated over the trailing 1-year period | 44.98% | 19.96% | +25.02% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 133.49% | 22.93% | +110.56% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 116.66% | 22.03% | +94.63% |
Dividends
MDGL vs. COST - Dividend Comparison
MDGL has not paid dividends to shareholders, while COST's dividend yield for the trailing twelve months is around 0.72%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
COST Costco Wholesale Corporation | 0.58% | 0.59% | 0.49% | 2.87% | 0.76% | 0.54% | 3.38% | 0.86% | 1.08% | 4.81% | 1.09% | 4.06% |
MDGL Madrigal Pharmaceuticals, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Financials
MDGL vs. COST - Financials Comparison
This section allows you to compare key financial metrics between Madrigal Pharmaceuticals, Inc. and Costco Wholesale Corporation. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
MDGL vs. COST - Profitability Comparison
MDGL - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Madrigal Pharmaceuticals, Inc. reported a gross profit of 324.25M and revenue of 364.25M. Therefore, the gross margin over that period was 89.0%.
COST - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Costco Wholesale Corporation reported a gross profit of -17.68B and revenue of 70.53B. Therefore, the gross margin over that period was -25.1%.
MDGL - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Madrigal Pharmaceuticals, Inc. reported an operating income of -56.31M and revenue of 364.25M, resulting in an operating margin of -15.5%.
COST - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Costco Wholesale Corporation reported an operating income of 2.82B and revenue of 70.53B, resulting in an operating margin of 4.0%.
MDGL - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Madrigal Pharmaceuticals, Inc. reported a net income of -57.94M and revenue of 364.25M, resulting in a net margin of -15.9%.
COST - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Costco Wholesale Corporation reported a net income of 2.19B and revenue of 70.53B, resulting in a net margin of 3.1%.
Frequently Asked Questions
MDGL and COST have a correlation of -0.08, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
MDGL has higher volatility (15.14%) compared to COST (7.34%). In terms of maximum drawdown, MDGL dropped -98.40% vs COST's -53.39%.
MDGL currently has the higher Sharpe Ratio (1.22 vs 0.10), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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