PortfoliosLab logoPortfoliosLab logo
MDGL vs. ABBV
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

MDGL vs. ABBV - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Madrigal Pharmaceuticals, Inc. (MDGL) and AbbVie Inc. (ABBV). The values are adjusted to include any dividend payments, if applicable.

Loading charts...

Returns By Period

In the year-to-date period, MDGL achieves a -16.17% return, which is significantly lower than ABBV's -3.41% return. Over the past 10 years, MDGL has outperformed ABBV with an annualized return of 43.76%, while ABBV has yielded a comparatively lower 17.56% annualized return.


MDGL

1D
7.79%
1M
-5.88%
YTD
-16.17%
6M
-15.82%
1Y
71.64%
3Y*
23.37%
5Y*
37.02%
10Y*
43.76%

ABBV

1D
0.80%
1M
4.31%
YTD
-3.41%
6M
-4.15%
1Y
19.73%
3Y*
20.88%
5Y*
18.44%
10Y*
17.56%
*Multi-year figures are annualized to reflect compound growth (CAGR)

MDGL vs. ABBV - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
MDGL
Madrigal Pharmaceuticals, Inc.
-16.17%88.72%33.36%-20.28%242.52%-23.77%22.02%-19.17%22.80%516.04%
ABBV
AbbVie Inc.
-3.41%33.08%18.86%-0.23%24.01%32.43%27.72%1.47%-0.96%60.07%

Correlation

The correlation between MDGL and ABBV is 0.24, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.24

Correlation (3Y)
Calculated over the trailing 3-year period

0.19

Correlation (5Y)
Calculated over the trailing 5-year period

0.17

Correlation (10Y)
Calculated over the trailing 10-year period

0.22

Correlation (All Time)
Calculated using the full available price history since Jan 3, 2013

0.23

Fundamentals

Market Cap

MDGL:

$14.17B

ABBV:

$385.19B

EPS

MDGL:

-$12.87

ABBV:

$2.05

PS Ratio

MDGL:

10.36

ABBV:

6.13

PB Ratio

MDGL:

26.08

ABBV:

14.01

Total Revenue (TTM)

MDGL:

$1.13B

ABBV:

$62.82B

Gross Profit (TTM)

MDGL:

$1.05B

ABBV:

$46.15B

EBITDA (TTM)

MDGL:

-$287.63M

ABBV:

$17.96B

Compare stocks, funds, or ETFs

Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.


Return for Risk

MDGL vs. ABBV — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

MDGL
MDGL Risk / Return Rank: 7979
Overall Rank
MDGL Sharpe Ratio Rank: 8282
Sharpe Ratio Rank
MDGL Sortino Ratio Rank: 8181
Sortino Ratio Rank
MDGL Omega Ratio Rank: 7878
Omega Ratio Rank
MDGL Calmar Ratio Rank: 7878
Calmar Ratio Rank
MDGL Martin Ratio Rank: 7676
Martin Ratio Rank

ABBV
ABBV Risk / Return Rank: 6262
Overall Rank
ABBV Sharpe Ratio Rank: 6666
Sharpe Ratio Rank
ABBV Sortino Ratio Rank: 6060
Sortino Ratio Rank
ABBV Omega Ratio Rank: 5959
Omega Ratio Rank
ABBV Calmar Ratio Rank: 6363
Calmar Ratio Rank
ABBV Martin Ratio Rank: 6363
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MDGL vs. ABBV - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Madrigal Pharmaceuticals, Inc. (MDGL) and AbbVie Inc. (ABBV). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


MDGLABBVDifference

Sharpe ratio

Return per unit of total volatility

1.57

0.83

+0.74

Sortino ratio

Return per unit of downside risk

2.44

1.30

+1.14

Omega ratio

Gain probability vs. loss probability

1.29

1.16

+0.13

Calmar ratio

Return relative to maximum drawdown

2.45

1.14

+1.31

Martin ratio

Return relative to average drawdown

5.56

2.57

+2.98

MDGL vs. ABBV - Sharpe Ratio Comparison

The current MDGL Sharpe Ratio is 1.57, which is higher than the ABBV Sharpe Ratio of 0.83. The chart below compares the historical Sharpe Ratios of MDGL and ABBV, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


Loading charts...

Sharpe Ratios by Period


MDGLABBVDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

1.57

0.83

+0.74

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

0.28

0.81

-0.53

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

0.37

0.68

-0.31

Sharpe Ratio (All Time)

Calculated using the full available price history

0.02

0.73

-0.71

Drawdowns

MDGL vs. ABBV - Drawdown Comparison

The maximum MDGL drawdown since its inception was -98.40%, which is greater than ABBV's maximum drawdown of -45.09%. Use the drawdown chart below to compare losses from any high point for MDGL and ABBV.


Loading charts...

Drawdown Indicators


MDGLABBVDifference

Max Drawdown

Largest peak-to-trough decline

-98.40%

-45.09%

-53.31%

Max Drawdown (1Y)

Largest decline over 1 year

-29.36%

-17.32%

-12.04%

Max Drawdown (3Y)

Largest decline over 3 years

-56.45%

-20.74%

-35.71%

Max Drawdown (5Y)

Largest decline over 5 years

-61.41%

-21.92%

-39.49%

Max Drawdown (10Y)

Largest decline over 10 years

-82.19%

-45.09%

-37.10%

Current Drawdown

Current decline from peak

-19.02%

-9.04%

-9.98%

Average Drawdown

Average peak-to-trough decline

-58.56%

-10.73%

-47.83%

Ulcer Index

Depth and duration of drawdowns from previous peaks

12.94%

7.69%

+5.25%

Volatility

MDGL vs. ABBV - Volatility Comparison

Madrigal Pharmaceuticals, Inc. (MDGL) has a higher volatility of 16.33% compared to AbbVie Inc. (ABBV) at 5.42%. This indicates that MDGL's price experiences larger fluctuations and is considered to be riskier than ABBV based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


Loading charts...

Volatility by Period


MDGLABBVDifference

Volatility (1M)

Calculated over the trailing 1-month period

16.33%

5.42%

+10.91%

Volatility (6M)

Calculated over the trailing 6-month period

31.56%

17.61%

+13.95%

Volatility (1Y)

Calculated over the trailing 1-year period

46.14%

23.96%

+22.18%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

133.42%

22.84%

+110.58%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

117.52%

25.74%

+91.78%

Dividends

MDGL vs. ABBV - Dividend Comparison

MDGL has not paid dividends to shareholders, while ABBV's dividend yield for the trailing twelve months is around 3.10%.


PositionTTM20252024202320222021202020192018201720162015
ABBV
AbbVie Inc.
3.10%2.87%3.49%3.82%3.49%3.84%4.41%4.83%3.89%2.65%3.64%3.41%
MDGL
Madrigal Pharmaceuticals, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%

Financials

MDGL vs. ABBV - Financials Comparison

This section allows you to compare key financial metrics between Madrigal Pharmaceuticals, Inc. and AbbVie Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.005.00B10.00B15.00B20222023202420252026
311.34M
15.00B
(MDGL) Total Revenue
(ABBV) Total Revenue
Values in USD except per share items

MDGL vs. ABBV - Profitability Comparison

The chart below illustrates the profitability comparison between Madrigal Pharmaceuticals, Inc. and AbbVie Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

50.0%60.0%70.0%80.0%90.0%100.0%20222023202420252026
91.4%
83.5%
Portfolio components
MDGL - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Madrigal Pharmaceuticals, Inc. reported a gross profit of 284.49M and revenue of 311.34M. Therefore, the gross margin over that period was 91.4%.

ABBV - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, AbbVie Inc. reported a gross profit of 12.53B and revenue of 15.00B. Therefore, the gross margin over that period was 83.5%.

MDGL - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Madrigal Pharmaceuticals, Inc. reported an operating income of -92.72M and revenue of 311.34M, resulting in an operating margin of -29.8%.

ABBV - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, AbbVie Inc. reported an operating income of 4.73B and revenue of 15.00B, resulting in an operating margin of 31.6%.

MDGL - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Madrigal Pharmaceuticals, Inc. reported a net income of -94.39M and revenue of 311.34M, resulting in a net margin of -30.3%.

ABBV - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, AbbVie Inc. reported a net income of 699.00M and revenue of 15.00B, resulting in a net margin of 4.7%.


Frequently Asked Questions


MDGL and ABBV have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

MDGL has higher volatility (16.33%) compared to ABBV (5.42%). In terms of maximum drawdown, MDGL dropped -98.40% vs ABBV's -45.09%.

MDGL currently has the higher Sharpe Ratio (1.57 vs 0.83), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for MDGL and ABBV

Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.

Open Portfolio Optimizer