LABD vs. SBIO
LABD (Direxion Daily S&P Biotech Bear 3x Shares) and SBIO (ALPS Medical Breakthroughs ETF) are both exchange-traded funds - LABD is a Leveraged Equities fund tracking the S&P Biotechnology Select Industry Index (-300%), while SBIO is a Health & Biotech Equities fund tracking the S-Network Medical Breakthroughs Index. Both are passively managed. Over the past 10 years, LABD returned -56.11%/yr vs 8.02%/yr for SBIO. At a correlation of -0.95, they often move in opposite directions. LABD charges 1.06%/yr vs 0.50%/yr for SBIO.
Performance
LABD vs. SBIO - Performance Comparison
Loading charts...
Returns By Period
In the year-to-date period, LABD achieves a -29.83% return, which is significantly lower than SBIO's -0.39% return. Over the past 10 years, LABD has underperformed SBIO with an annualized return of -56.11%, while SBIO has yielded a comparatively higher 8.02% annualized return.
LABD
- 1D
- -4.73%
- 1M
- 4.70%
- YTD
- -29.83%
- 6M
- -31.22%
- 1Y
- -80.27%
- 3Y*
- -49.85%
- 5Y*
- -41.45%
- 10Y*
- -56.11%
SBIO
- 1D
- 1.41%
- 1M
- -7.56%
- YTD
- -0.39%
- 6M
- 3.05%
- 1Y
- 65.41%
- 3Y*
- 17.80%
- 5Y*
- 2.68%
- 10Y*
- 8.02%
LABD vs. SBIO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
LABD Direxion Daily S&P Biotech Bear 3x Shares | -29.83% | -70.07% | -21.43% | -41.77% | -32.68% | 1.86% | -89.75% | -70.80% | -6.26% | -75.67% |
SBIO ALPS Medical Breakthroughs ETF | -0.39% | 55.07% | 3.81% | 8.68% | -28.08% | -17.55% | 21.17% | 50.30% | -11.81% | 45.67% |
Correlation
The correlation between LABD and SBIO is -0.95, meaning they tend to move in opposite directions. This is especially valuable for risk management - when one declines, the other has historically tended to hold steady or rise.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | -0.95 |
Correlation (3Y) Calculated over the trailing 3-year period | -0.93 |
Correlation (5Y) Calculated over the trailing 5-year period | -0.95 |
Correlation (10Y) Calculated over the trailing 10-year period | -0.95 |
Correlation (All Time) Calculated using the full available price history since May 29, 2015 | -0.95 |
The correlation between LABD and SBIO has been stable across timeframes, ranging from -0.95 to -0.93 - a consistent structural relationship.
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
Return for Risk
LABD vs. SBIO — Risk / Return Rank
LABD
SBIO
LABD vs. SBIO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Direxion Daily S&P Biotech Bear 3x Shares (LABD) and ALPS Medical Breakthroughs ETF (SBIO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| LABD | SBIO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -3.30 | ||
| Sortino ratioReturn per unit of downside risk | -5.32 | ||
| Omega ratioGain probability vs. loss probability | 0.75 | 1.36 | -0.61 |
| Calmar ratioReturn relative to maximum drawdown | -0.97 | 5.19 | -6.16 |
| Martin ratioReturn relative to average drawdown | -1.31 | 15.57 | -16.87 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
Loading charts...
Sharpe Ratios by Period
| LABD | SBIO | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | -1.06 | 2.24 | -3.30 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.43 | 0.08 | -0.51 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | -0.59 | 0.24 | -0.83 |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.54 | 0.21 | -0.76 |
Drawdowns
LABD vs. SBIO - Drawdown Comparison
The maximum LABD drawdown since its inception was -99.99%, which is greater than SBIO's maximum drawdown of -63.06%. Use the drawdown chart below to compare losses from any high point for LABD and SBIO.
Loading charts...
Drawdown Indicators
| LABD | SBIO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.99% | -63.06% | -36.93% |
Max Drawdown (1Y)Largest decline over 1 year | -83.21% | -12.66% | -70.55% |
Max Drawdown (3Y)Largest decline over 3 years | -95.31% | -42.44% | -52.87% |
Max Drawdown (5Y)Largest decline over 5 years | -98.24% | -53.10% | -45.14% |
Max Drawdown (10Y)Largest decline over 10 years | -99.98% | -63.06% | -36.92% |
Current DrawdownCurrent decline from peak | -99.99% | -16.79% | -83.20% |
Average DrawdownAverage peak-to-trough decline | -90.92% | -28.45% | -62.47% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 61.36% | 4.22% | +57.14% |
Volatility
LABD vs. SBIO - Volatility Comparison
Direxion Daily S&P Biotech Bear 3x Shares (LABD) has a higher volatility of 27.46% compared to ALPS Medical Breakthroughs ETF (SBIO) at 9.48%. This indicates that LABD's price experiences larger fluctuations and is considered to be riskier than SBIO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading charts...
Volatility by Period
| LABD | SBIO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 27.46% | 9.48% | +17.98% |
Volatility (6M)Calculated over the trailing 6-month period | 61.67% | 22.70% | +38.97% |
Volatility (1Y)Calculated over the trailing 1-year period | 75.77% | 29.42% | +46.35% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 96.26% | 33.56% | +62.70% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 95.93% | 33.17% | +62.76% |
LABD vs. SBIO - Expense Ratio Comparison
LABD has a 1.06% expense ratio, which is higher than SBIO's 0.50% expense ratio.
Dividends
LABD vs. SBIO - Dividend Comparison
LABD's dividend yield for the trailing twelve months is around 6.45%, while SBIO has not paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
LABD Direxion Daily S&P Biotech Bear 3x Shares | 6.45% | 6.67% | 4.68% | 6.13% | 0.53% | 0.00% | 3.94% | 1.75% | 0.81% | 0.00% |
SBIO ALPS Medical Breakthroughs ETF | 0.00% | 0.00% | 3.55% | 0.22% | 0.00% | 0.00% | 0.00% | 0.04% | 2.79% | 1.77% |
Frequently Asked Questions
LABD and SBIO have a correlation of -0.95, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
LABD has higher volatility (27.46%) compared to SBIO (9.48%). In terms of maximum drawdown, LABD dropped -99.99% vs SBIO's -63.06%.
On 10-year performance, SBIO leads with 8.02% vs -56.11% for LABD. On fees, SBIO is cheaper at 0.50% per year. On volatility, SBIO has been the lower-risk option at 9.48%. The better choice depends on whether you care most about return, fees, risk, or income.
Over the 10-year period, SBIO has performed better with a 8.02% return vs -56.11%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.
SBIO is cheaper with a 0.50% expense ratio, compared with 1.06% for LABD.
LABD has the higher dividend yield at 6.45%, compared with 0.00% for SBIO.
LABD is categorized as Leveraged Equities, while SBIO is Health & Biotech Equities. LABD tracks S&P Biotechnology Select Industry Index (-300%), while SBIO tracks S-Network Medical Breakthroughs Index. They also come from different issuers: Direxion and SS&C. Their fees differ too: 1.06% for LABD and 0.50% for SBIO.
SBIO currently has the higher Sharpe Ratio (2.24 vs -1.06), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
Find the right allocation for LABD and SBIO
Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.
Open Portfolio Optimizer