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KPTI vs. QVCGA
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

KPTI vs. QVCGA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Karyopharm Therapeutics Inc. (KPTI) and QVC Group Inc (QVCGA). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period


KPTI

1D
-6.39%
1M
-1.62%
YTD
15.49%
6M
44.31%
1Y
89.31%
3Y*
-36.47%
5Y*
-43.70%
10Y*
-23.75%

QVCGA

1D
0.00%
1M
YTD
6M
1Y
3Y*
5Y*
10Y*
*Multi-year figures are annualized to reflect compound growth (CAGR)

KPTI vs. QVCGA - Yearly Performance Comparison


2026 (YTD)
KPTI
Karyopharm Therapeutics Inc.
-6.70%
QVCGA
QVC Group Inc
0.00%

Fundamentals

Market Cap

KPTI:

$210.08M

QVCGA:

$2.75M

EPS

KPTI:

-$13.00

QVCGA:

-$302.09

PS Ratio

KPTI:

0.84

QVCGA:

0.00

Total Revenue (TTM)

KPTI:

$151.12M

QVCGA:

$9.23B

Gross Profit (TTM)

KPTI:

$145.13M

QVCGA:

$2.89B

EBITDA (TTM)

KPTI:

-$93.05M

QVCGA:

$789.00M

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Return for Risk

KPTI vs. QVCGA — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

KPTI
KPTI Risk / Return Rank: 7373
Overall Rank
KPTI Sharpe Ratio Rank: 7272
Sharpe Ratio Rank
KPTI Sortino Ratio Rank: 7676
Sortino Ratio Rank
KPTI Omega Ratio Rank: 7171
Omega Ratio Rank
KPTI Calmar Ratio Rank: 7474
Calmar Ratio Rank
KPTI Martin Ratio Rank: 7575
Martin Ratio Rank

QVCGA
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

KPTI vs. QVCGA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Karyopharm Therapeutics Inc. (KPTI) and QVC Group Inc (QVCGA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


KPTIQVCGADifference
Sharpe ratioReturn per unit of total volatility

Sortino ratioReturn per unit of downside risk

Omega ratioGain probability vs. loss probability

1.22

Calmar ratioReturn relative to maximum drawdown

1.86

Martin ratioReturn relative to average drawdown

4.59

KPTI vs. QVCGA - Sharpe Ratio Comparison


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Sharpe Ratios by Period


KPTIQVCGADifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

0.95

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

-0.46

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

-0.28

Sharpe Ratio (All Time)

Calculated using the full available price history

-0.27

Drawdowns

KPTI vs. QVCGA - Drawdown Comparison

The maximum KPTI drawdown since its inception was -99.50%, which is greater than QVCGA's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for KPTI and QVCGA.


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Drawdown Indicators


KPTIQVCGADifference

Max Drawdown

Largest peak-to-trough decline

-99.50%

0.00%

-99.50%

Max Drawdown (1Y)

Largest decline over 1 year

-48.36%

Max Drawdown (3Y)

Largest decline over 3 years

-89.32%

Max Drawdown (5Y)

Largest decline over 5 years

-98.36%

Max Drawdown (10Y)

Largest decline over 10 years

-99.15%

Current Drawdown

Current decline from peak

-98.80%

0.00%

-98.80%

Average Drawdown

Average peak-to-trough decline

-75.28%

0.00%

-75.28%

Ulcer Index

Depth and duration of drawdowns from previous peaks

19.53%

Volatility

KPTI vs. QVCGA - Volatility Comparison


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Volatility by Period


KPTIQVCGADifference

Volatility (1M)

Calculated over the trailing 1-month period

24.86%

Volatility (6M)

Calculated over the trailing 6-month period

62.32%

Volatility (1Y)

Calculated over the trailing 1-year period

94.32%

0.00%

+94.32%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

94.91%

0.00%

+94.91%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

86.51%

0.00%

+86.51%

Dividends

KPTI vs. QVCGA - Dividend Comparison

Neither KPTI nor QVCGA has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

KPTI vs. QVCGA - Financials Comparison

This section allows you to compare key financial metrics between Karyopharm Therapeutics Inc. and QVC Group Inc. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.001.00B2.00B3.00B4.00B20222023202420252026
35.07M
2.68B
(KPTI) Total Revenue
(QVCGA) Total Revenue
Values in USD except per share items

KPTI vs. QVCGA - Profitability Comparison

The chart below illustrates the profitability comparison between Karyopharm Therapeutics Inc. and QVC Group Inc over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

20.0%40.0%60.0%80.0%100.0%20222023202420252026
96.2%
22.7%
Portfolio components
KPTI - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Karyopharm Therapeutics Inc. reported a gross profit of 33.72M and revenue of 35.07M. Therefore, the gross margin over that period was 96.2%.

QVCGA - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, QVC Group Inc reported a gross profit of 608.00M and revenue of 2.68B. Therefore, the gross margin over that period was 22.7%.

KPTI - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Karyopharm Therapeutics Inc. reported an operating income of -26.76M and revenue of 35.07M, resulting in an operating margin of -76.3%.

QVCGA - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, QVC Group Inc reported an operating income of 106.00M and revenue of 2.68B, resulting in an operating margin of 4.0%.

KPTI - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Karyopharm Therapeutics Inc. reported a net income of -22.39M and revenue of 35.07M, resulting in a net margin of -63.9%.

QVCGA - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, QVC Group Inc reported a net income of -37.00M and revenue of 2.68B, resulting in a net margin of -1.4%.


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