JFNAX vs. LYFIX
Compare and contrast key facts about Janus Henderson Global Life Sciences Fund Class A (JFNAX) and AlphaCentric LifeSci Healthcare Fund (LYFIX).
JFNAX is managed by Janus Henderson. It was launched on Dec 31, 1998. LYFIX is managed by AlphaCentric Funds. It was launched on Nov 28, 2019.
Performance
JFNAX vs. LYFIX - Performance Comparison
Loading graphics...
JFNAX vs. LYFIX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|---|
JFNAX Janus Henderson Global Life Sciences Fund Class A | -3.77% | 24.61% | 3.41% | 7.35% | -2.86% | 6.59% | 25.42% | 4.07% |
LYFIX AlphaCentric LifeSci Healthcare Fund | -0.31% | 28.22% | -0.27% | 7.19% | -0.92% | -3.42% | 54.83% | 1.20% |
Returns By Period
In the year-to-date period, JFNAX achieves a -3.77% return, which is significantly lower than LYFIX's -0.31% return.
JFNAX
- 1D
- 3.08%
- 1M
- -5.56%
- YTD
- -3.77%
- 6M
- 11.78%
- 1Y
- 21.47%
- 3Y*
- 10.49%
- 5Y*
- 7.15%
- 10Y*
- 10.96%
LYFIX
- 1D
- 4.07%
- 1M
- -3.00%
- YTD
- -0.31%
- 6M
- 16.38%
- 1Y
- 26.02%
- 3Y*
- 8.51%
- 5Y*
- 4.83%
- 10Y*
- —
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
JFNAX vs. LYFIX - Expense Ratio Comparison
JFNAX has a 0.98% expense ratio, which is lower than LYFIX's 1.40% expense ratio.
Return for Risk
JFNAX vs. LYFIX — Risk / Return Rank
JFNAX
LYFIX
JFNAX vs. LYFIX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Janus Henderson Global Life Sciences Fund Class A (JFNAX) and AlphaCentric LifeSci Healthcare Fund (LYFIX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| JFNAX | LYFIX | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 1.06 | 1.25 | -0.19 |
Sortino ratioReturn per unit of downside risk | 1.52 | 1.79 | -0.27 |
Omega ratioGain probability vs. loss probability | 1.20 | 1.22 | -0.02 |
Calmar ratioReturn relative to maximum drawdown | 1.78 | 2.36 | -0.59 |
Martin ratioReturn relative to average drawdown | 4.89 | 5.75 | -0.86 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
Loading graphics...
Sharpe Ratios by Period
| JFNAX | LYFIX | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.06 | 1.25 | -0.19 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.46 | 0.21 | +0.25 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.63 | — | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.83 | 0.51 | +0.32 |
Correlation
The correlation between JFNAX and LYFIX is 0.80, which is considered to be high. That indicates a strong positive relationship between their price movements. Having highly-correlated positions in a portfolio may signal a lack of diversification, potentially leading to increased risk during market downturns.
Dividends
JFNAX vs. LYFIX - Dividend Comparison
JFNAX's dividend yield for the trailing twelve months is around 4.73%, more than LYFIX's 1.79% yield.
| TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
JFNAX Janus Henderson Global Life Sciences Fund Class A | 4.73% | 4.56% | 5.74% | 4.28% | 0.08% | 9.90% | 7.82% | 6.18% | 13.55% | 1.03% | 0.97% | 8.93% |
LYFIX AlphaCentric LifeSci Healthcare Fund | 1.79% | 1.78% | 2.24% | 2.63% | 4.43% | 12.88% | 2.30% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Drawdowns
JFNAX vs. LYFIX - Drawdown Comparison
The maximum JFNAX drawdown since its inception was -31.07%, smaller than the maximum LYFIX drawdown of -35.33%. Use the drawdown chart below to compare losses from any high point for JFNAX and LYFIX.
Loading graphics...
Drawdown Indicators
| JFNAX | LYFIX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -31.07% | -35.33% | +4.26% |
Max Drawdown (1Y)Largest decline over 1 year | -9.71% | -9.47% | -0.24% |
Max Drawdown (5Y)Largest decline over 5 years | -22.29% | -32.45% | +10.16% |
Max Drawdown (10Y)Largest decline over 10 years | -27.39% | — | — |
Current DrawdownCurrent decline from peak | -6.65% | -3.88% | -2.77% |
Average DrawdownAverage peak-to-trough decline | -6.31% | -10.07% | +3.76% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 3.63% | 4.24% | -0.61% |
Volatility
JFNAX vs. LYFIX - Volatility Comparison
The current volatility for Janus Henderson Global Life Sciences Fund Class A (JFNAX) is 6.00%, while AlphaCentric LifeSci Healthcare Fund (LYFIX) has a volatility of 7.96%. This indicates that JFNAX experiences smaller price fluctuations and is considered to be less risky than LYFIX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading graphics...
Volatility by Period
| JFNAX | LYFIX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 6.00% | 7.96% | -1.96% |
Volatility (6M)Calculated over the trailing 6-month period | 10.64% | 13.70% | -3.06% |
Volatility (1Y)Calculated over the trailing 1-year period | 17.86% | 19.38% | -1.52% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 15.70% | 22.93% | -7.23% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 17.41% | 23.50% | -6.09% |