- ISIN
- US4710234810
- Issuer
- Janus Henderson
- Inception Date
- Dec 31, 1998
- Category
- Health & Biotech Equities
- Min. Investment
- $2,500
- Distribution Policy
- Distributing
- Asset Class
- Equity
- Asset Class Size
- Large-Cap
- Asset Class Style
- Growth
Share Price Chart
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Performance
JFNAX Performance Chart
Janus Henderson Global Life Sciences Fund Class A (JFNAX) is up 0.5% since the beginning of the year. JFNAX is currently trading at $79 per share. Investors who bought $1,000 worth of JFNAX shares 5 years ago would now be looking at an investment worth $1,402.
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Returns By Period
Janus Henderson Global Life Sciences Fund Class A (JFNAX) has returned 0.49% so far this year and 30.95% over the past 12 months. Over the last ten years, JFNAX has returned 11.10% per year, falling short of the S&P 500 Index benchmark, which averaged 13.88% annually.
Janus Henderson Global Life Sciences Fund Class A
- 1D
- -0.39%
- 1M
- 0.71%
- YTD
- 0.49%
- 6M
- -0.05%
- 1Y
- 30.95%
- 3Y*
- 10.06%
- 5Y*
- 6.99%
- 10Y*
- 11.10%
Benchmark (S&P 500 Index)
- 1D
- -0.37%
- 1M
- -0.01%
- YTD
- 9.16%
- 6M
- 8.64%
- 1Y
- 25.22%
- 3Y*
- 19.78%
- 5Y*
- 11.99%
- 10Y*
- 13.88%
JFNAX Monthly Returns History
Based on dividend-adjusted daily data since Jul 6, 2009, JFNAX's average daily return is +0.06%, while the average monthly return is +1.24%. At this rate, an investment would double in approximately 4.7 years.
Historically, 66% of months were positive and 34% were negative. The best month was Apr 2020 with a return of +12.6%, while the worst month was Jan 2016 at -13.4%. The longest winning streak lasted 9 consecutive months, and the longest losing streak was 4 months.
On a daily basis, JFNAX closed higher 54% of trading days. The best single day was Mar 24, 2020 with a return of +7.0%, while the worst single day was Mar 16, 2020 at -10.4%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 0.77% | 2.04% | -6.41% | 1.79% | 2.42% | 0.16% | 0.49% | ||||||
| 2025 | 5.92% | -0.23% | -4.47% | -0.31% | -5.70% | 2.31% | -0.87% | 6.12% | 2.87% | 8.69% | 9.25% | -0.12% | 24.61% |
| 2024 | 2.75% | 3.83% | 1.71% | -4.67% | 3.56% | 3.19% | 2.65% | 5.17% | -2.43% | -3.29% | -0.72% | -7.51% | 3.41% |
| 2023 | 0.47% | -4.34% | 2.67% | 4.01% | -2.33% | 2.99% | 1.00% | -1.40% | -3.76% | -6.13% | 7.45% | 7.56% | 7.35% |
| 2022 | -9.06% | 0.57% | 3.58% | -6.73% | -0.92% | -0.78% | 3.65% | -2.56% | -2.89% | 8.54% | 6.00% | -0.90% | -2.86% |
| 2021 | -0.86% | 0.07% | -1.93% | 3.11% | 0.23% | 3.58% | 0.14% | 3.18% | -4.08% | 4.47% | -7.41% | 6.75% | 6.59% |
Benchmark Metrics
Janus Henderson Global Life Sciences Fund Class A has an annualized alpha of 4.00%, beta of 0.81, and R2 of 0.63 versus S&P 500 Index. Calculated based on daily prices since July 06, 2009.
- This fund participates in less of S&P 500 Index's moves in both directions, but captures a larger share of gains (92.13%) than losses (82.72%) - typical of diversified or defensive assets.
- This fund generated an annualized alpha of 4.00% versus S&P 500 Index - delivering returns beyond what market exposure alone would predict.
- Alpha
- 4.00%
- Beta
- 0.81
- R²
- 0.63
- Upside Capture
- 92.13%
- Downside Capture
- 82.72%
Expense Ratio
JFNAX has a high expense ratio of 0.98%, indicating above-average management fees.
Return for Risk
Risk / Return Rank
JFNAX ranks 58 for risk / return — on par with similar mutual funds. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for Janus Henderson Global Life Sciences Fund Class A (JFNAX) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| JFNAX | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.01 | ||
| Sortino ratioReturn per unit of downside risk | +0.21 | ||
| Omega ratioGain probability vs. loss probability | 1.35 | 1.37 | -0.01 |
| Calmar ratioReturn relative to maximum drawdown | 3.15 | 2.78 | +0.37 |
| Martin ratioReturn relative to average drawdown | 10.01 | 12.44 | -2.43 |
Dividends
Dividend History
Janus Henderson Global Life Sciences Fund Class A provided a 4.53% dividend yield over the last twelve months, with an annual payout of $3.59 per share.
| Period | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend | $3.59 | $3.59 | $3.80 | $2.89 | $0.05 | $6.71 | $5.47 | $3.72 | $6.72 | $0.56 | $0.43 | $4.60 |
Dividend yield | 4.53% | 4.56% | 5.74% | 4.28% | 0.08% | 9.90% | 7.82% | 6.18% | 13.55% | 1.03% | 0.97% | 8.93% |
Monthly Dividends
The table displays the monthly dividend distributions for Janus Henderson Global Life Sciences Fund Class A. The dividends shown in the table have been adjusted to account for any splits that may have occurred.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | ||||||
| 2025 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $3.59 | $3.59 |
| 2024 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $3.80 | $3.80 |
| 2023 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.02 | $2.87 | $2.89 |
| 2022 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.05 | $0.05 |
| 2021 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $6.71 | $6.71 |
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Janus Henderson Global Life Sciences Fund Class A. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Janus Henderson Global Life Sciences Fund Class A was 31.07%, occurring on Feb 8, 2016. Recovery took 496 trading sessions.
The current Janus Henderson Global Life Sciences Fund Class A drawdown is 2.52%.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
2016 bear market2016 | -31.07%Feb 2016 | 6mo 22d | 1y 11mo | 2y 6moJul 2015 - Jan 2018 |
COVID crash2020 | -27.39%Mar 2020 | 1mo 2d | 2mo 17d | 3mo 19dFeb 2020 - Jun 2020 |
Bear market2022 | -22.29%Jun 2022 | 7mo 14d | 1y 6mo | 2y 1moNov 2021 - Dec 2023 |
2025 selloff2025 | -21.28%Apr 2025 | 7mo 7d | 7mo 6d | 1y 2moSep 2024 - Nov 2025 |
Rate-hike selloffLate 2018 | -18.67%Dec 2018 | 2mo 24d | 3mo 12d | 6mo 6dOct 2018 - Apr 2019 |
Drawdown Indicators
| JFNAX | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -31.07% | -56.78% | +25.71% |
Max Drawdown (1Y)Largest decline over 1 year | -9.71% | -9.10% | -0.61% |
Max Drawdown (3Y)Largest decline over 3 years | -21.28% | -18.90% | -2.38% |
Max Drawdown (5Y)Largest decline over 5 years | -22.29% | -25.43% | +3.14% |
Max Drawdown (10Y)Largest decline over 10 years | -27.39% | -33.92% | +6.53% |
Current DrawdownCurrent decline from peak | -2.52% | -1.80% | -0.72% |
Average DrawdownAverage peak-to-trough decline | -6.28% | -10.71% | +4.43% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 3.06% | 2.03% | +1.03% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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