GSKH vs. XLVI

Last updated Aug 6, 2026

GSKH (GSK plc ADRhedged ETF) and XLVI (State Street Health Care Select Sector SPDR Premium Income ETF) are both exchange-traded funds - GSKH is a Health & Biotech Equities fund tracking the GSK plc Local Shares Total Return, while XLVI is a Derivative Income fund actively managed by State Street. GSKH is passively managed, while XLVI is actively managed. Over the past year, GSKH returned 39.31% vs 22.82% for XLVI. Their 0.58 correlation means they have sometimes moved together and sometimes differently. GSKH charges 0.19%/yr vs 0.35%/yr for XLVI.

Performance

GSKH vs. XLVI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in GSK plc ADRhedged ETF (GSKH) and State Street Health Care Select Sector SPDR Premium Income ETF (XLVI). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, GSKH achieves a 6.53% return, which is significantly lower than XLVI's 7.87% return.

GSKH

• 1D: -0.18%
• 1M: -3.69%
• 6M: -7.83%
• YTD: 6.53%
• 1Y: 39.31%
• 3Y*: —
• 5Y*: —
• 10Y*: —
• ALL TIME*: 26.86%

XLVI

• 1D: 1.06%
• 1M: 1.95%
• 6M: 6.75%
• YTD: 7.87%
• 1Y: 22.82%
• 3Y*: —
• 5Y*: —
• 10Y*: —
• ALL TIME*: 20.89%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
GSKH GSK plc ADRhedged ETF	$36.19K	$35.33K	$34.24K
XLVI State Street Health Care Select Sector SPDR Premium Income ETF	$948.55K	$699.60K	$493.15K

GSKH vs. XLVI - Yearly Performance Comparison

	2026 (YTD)	2025
GSKH GSK plc ADRhedged ETF	6.53%	29.95%
XLVI State Street Health Care Select Sector SPDR Premium Income ETF	7.87%	12.41%

Correlation

The correlation between GSKH and XLVI is 0.59, which is moderate. They have sometimes moved together and sometimes differently, sharing some price drivers without tracking each other closely.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.59
Correlation (All Time) Calculated using the full available price history since Jul 30, 2025	0.58

The correlation between GSKH and XLVI has been stable across timeframes, ranging from 0.58 to 0.59 - a consistent structural relationship.

Return for Risk

GSKH vs. XLVI — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

GSKH

GSKH Risk / Return Rank: 52
GSKH Sharpe Ratio Rank: 54
GSKH Sortino Ratio Rank: 61
GSKH Omega Ratio Rank: 55
GSKH Calmar Ratio Rank: 51
GSKH Martin Ratio Rank: 40

XLVI

XLVI Risk / Return Rank: 77
XLVI Sharpe Ratio Rank: 83
XLVI Sortino Ratio Rank: 87
XLVI Omega Ratio Rank: 85
XLVI Calmar Ratio Rank: 71
XLVI Martin Ratio Rank: 59

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

GSKH vs. XLVI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for GSK plc ADRhedged ETF (GSKH) and State Street Health Care Select Sector SPDR Premium Income ETF (XLVI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	GSKH	XLVI	Difference
Sharpe ratio: Return per unit of total volatility	1.52	2.14	-0.63
Sortino ratio: Return per unit of downside risk	2.34	3.22	-0.88
Omega ratio: Gain probability vs. loss probability	1.28	1.41	-0.12
Calmar ratio: Return relative to maximum drawdown	2.13	2.81	-0.68
Martin ratio: Return relative to average drawdown	4.78	7.98	-3.20

GSKH vs. XLVI - Sharpe Ratio Comparison

The current GSKH Sharpe Ratio is 1.52, which is comparable to the XLVI Sharpe Ratio of 2.14. The chart below compares the historical Sharpe Ratios of GSKH and XLVI, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

GSKH vs. XLVI - Drawdown Comparison

The maximum GSKH drawdown since its inception was -18.54%, which is greater than XLVI's maximum drawdown of -8.14%. Use the drawdown chart below to compare losses from any high point for GSKH and XLVI.

Drawdown Indicators

	GSKH	XLVI	Difference
Max Drawdown Largest peak-to-trough decline	-18.54%	-8.14%	-10.40%
Max Drawdown (1Y) Largest decline over 1 year	-18.54%	-8.14%	-10.40%
Current Drawdown Current decline from peak	-14.33%	-0.75%	-13.58%
Average Drawdown Average peak-to-trough decline	-6.39%	-1.77%	-4.62%
Ulcer Index Depth and duration of drawdowns from previous peaks	8.25%	2.88%	+5.37%

Volatility

GSKH vs. XLVI - Volatility Comparison

GSK plc ADRhedged ETF (GSKH) has a higher volatility of 7.99% compared to State Street Health Care Select Sector SPDR Premium Income ETF (XLVI) at 3.52%. This indicates that GSKH's price experiences larger fluctuations and is considered to be riskier than XLVI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	GSKH	XLVI	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.99%	3.52%	+4.47%
Volatility (6M) Calculated over the trailing 6-month period	19.31%	8.72%	+10.59%
Volatility (1Y) Calculated over the trailing 1-year period	26.07%	10.70%	+15.37%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	26.94%	11.04%	+15.90%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	26.94%	11.04%	+15.90%

GSKH vs. XLVI - Expense Ratio Comparison

GSKH has a 0.19% expense ratio, which is lower than XLVI's 0.35% expense ratio.

Dividends

GSKH vs. XLVI - Dividend Comparison

GSKH's dividend yield for the trailing twelve months is around 2.91%, less than XLVI's 12.64% yield.

Position	TTM	2025
GSKH GSK plc ADRhedged ETF	2.91%	1.15%
XLVI State Street Health Care Select Sector SPDR Premium Income ETF	12.64%	5.73%

Frequently Asked Questions

Can I hold both GSKH and XLVI in my portfolio?

GSKH and XLVI have a correlation of 0.59, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, GSKH or XLVI?

GSKH has higher volatility (7.99%) compared to XLVI (3.52%). In terms of maximum drawdown, GSKH dropped -18.54% vs XLVI's -8.14%.

Which ETF is better, GSKH or XLVI?

On 1-year performance, GSKH leads with 39.31% vs 22.82% for XLVI. On fees, GSKH is cheaper at 0.19% per year. On volatility, XLVI has been the lower-risk option at 3.52%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, GSKH or XLVI?

Over the 1-year period, GSKH has performed better with a 39.31% return vs 22.82%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, GSKH or XLVI?

GSKH is cheaper with a 0.19% expense ratio, compared with 0.35% for XLVI.

Which ETF pays a higher dividend yield, GSKH or XLVI?

XLVI has the higher dividend yield at 12.64%, compared with 2.91% for GSKH.

What is the main difference between GSKH and XLVI?

GSKH is categorized as Health & Biotech Equities, while XLVI is Derivative Income. They also come from different issuers: ADRhedged and State Street. Their fees differ too: 0.19% for GSKH and 0.35% for XLVI.

Which has better risk-adjusted returns?

XLVI currently has the higher Sharpe Ratio (2.14 vs 1.52), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.