EDOC vs. XLVI

Last updated Jun 24, 2026

EDOC (Global X Telemedicine & Digital Health ETF) and XLVI (State Street Health Care Select Sector SPDR Premium Income ETF) are both exchange-traded funds - EDOC is a Health & Biotech Equities fund tracking the Solactive Telemedicine & Digital Health Index- TR Net, while XLVI is a Derivative Income fund actively managed by State Street. EDOC is passively managed, while XLVI is actively managed. At a 0.46 correlation, their price movements are largely independent. EDOC charges 0.68%/yr vs 0.35%/yr for XLVI.

Performance

EDOC vs. XLVI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Global X Telemedicine & Digital Health ETF (EDOC) and State Street Health Care Select Sector SPDR Premium Income ETF (XLVI). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, EDOC achieves a -10.37% return, which is significantly lower than XLVI's 2.50% return.

EDOC

• 1D: 1.49%
• 1M: 5.54%
• YTD: -10.37%
• 6M: -12.67%
• 1Y: -16.13%
• 3Y*: -8.12%
• 5Y*: -14.64%
• 10Y*: —

XLVI

• 1D: 1.53%
• 1M: 2.15%
• YTD: 2.50%
• 6M: 2.57%
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

EDOC vs. XLVI - Yearly Performance Comparison

	2026 (YTD)	2025
EDOC Global X Telemedicine & Digital Health ETF	-10.37%	-7.59%
XLVI State Street Health Care Select Sector SPDR Premium Income ETF	2.50%	12.41%

Correlation

The correlation between EDOC and XLVI is 0.46, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (All Time) Calculated using the full available price history since Jul 30, 2025	0.46

Return for Risk

EDOC vs. XLVI — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

EDOC

EDOC Risk / Return Rank: 4
EDOC Sharpe Ratio Rank: 3
EDOC Sortino Ratio Rank: 3
EDOC Omega Ratio Rank: 4
EDOC Calmar Ratio Rank: 5
EDOC Martin Ratio Rank: 4

XLVI

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

EDOC vs. XLVI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Global X Telemedicine & Digital Health ETF (EDOC) and State Street Health Care Select Sector SPDR Premium Income ETF (XLVI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	EDOC	XLVI	Difference
Sharpe ratio: Return per unit of total volatility	-0.73	—	—
Sortino ratio: Return per unit of downside risk	-0.95	—	—
Omega ratio: Gain probability vs. loss probability	0.90	—	—
Calmar ratio: Return relative to maximum drawdown	-0.53	—	—
Martin ratio: Return relative to average drawdown	-1.01	—	—

Drawdowns

EDOC vs. XLVI - Drawdown Comparison

The maximum EDOC drawdown since its inception was -65.76%, which is greater than XLVI's maximum drawdown of -8.14%. Use the drawdown chart below to compare losses from any high point for EDOC and XLVI.

Drawdown Indicators

	EDOC	XLVI	Difference
Max Drawdown Largest peak-to-trough decline	-65.76%	-8.14%	-57.62%
Max Drawdown (1Y) Largest decline over 1 year	-30.71%	—	—
Max Drawdown (3Y) Largest decline over 3 years	-35.78%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-60.36%	—	—
Current Drawdown Current decline from peak	-61.31%	-0.97%	-60.34%
Average Drawdown Average peak-to-trough decline	-43.20%	-1.94%	-41.26%
Ulcer Index Depth and duration of drawdowns from previous peaks	15.98%	—	—

Volatility

Volatility by Period

	EDOC	XLVI	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.26%	—	—
Volatility (6M) Calculated over the trailing 6-month period	16.63%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	22.43%	11.06%	+11.37%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	26.46%	11.06%	+15.40%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	26.28%	11.06%	+15.22%

EDOC vs. XLVI - Expense Ratio Comparison

EDOC has a 0.68% expense ratio, which is higher than XLVI's 0.35% expense ratio.

Dividends

EDOC vs. XLVI - Dividend Comparison

EDOC's dividend yield for the trailing twelve months is around 0.37%, less than XLVI's 11.17% yield.

Position	TTM	2025	2024	2023	2022	2021	2020
EDOC Global X Telemedicine & Digital Health ETF	0.37%	0.33%	0.00%	0.00%	0.00%	0.00%	0.03%
XLVI State Street Health Care Select Sector SPDR Premium Income ETF	11.17%	5.73%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both EDOC and XLVI in my portfolio?

EDOC and XLVI have a correlation of 0.46, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, EDOC or XLVI?

On fees, XLVI is cheaper at 0.35% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, EDOC or XLVI?

XLVI is cheaper with a 0.35% expense ratio, compared with 0.68% for EDOC.

Which ETF pays a higher dividend yield, EDOC or XLVI?

XLVI has the higher dividend yield at 11.17%, compared with 0.37% for EDOC.

What is the main difference between EDOC and XLVI?

EDOC is categorized as Health & Biotech Equities, while XLVI is Derivative Income. They also come from different issuers: Global X and State Street. Their fees differ too: 0.68% for EDOC and 0.35% for XLVI.