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ISRG vs. PFE
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Correlation

The correlation between ISRG and PFE is 0.28, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


-0.50.00.51.00.3

Performance

ISRG vs. PFE - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Intuitive Surgical, Inc. (ISRG) and Pfizer Inc. (PFE). The values are adjusted to include any dividend payments, if applicable.

-10.00%0.00%10.00%20.00%30.00%AugustSeptemberOctoberNovemberDecember2025
23.03%
-7.80%
ISRG
PFE

Key characteristics

Sharpe Ratio

ISRG:

1.97

PFE:

-0.06

Sortino Ratio

ISRG:

3.08

PFE:

0.08

Omega Ratio

ISRG:

1.38

PFE:

1.01

Calmar Ratio

ISRG:

5.70

PFE:

-0.02

Martin Ratio

ISRG:

17.95

PFE:

-0.15

Ulcer Index

ISRG:

2.72%

PFE:

8.59%

Daily Std Dev

ISRG:

24.76%

PFE:

22.99%

Max Drawdown

ISRG:

-82.25%

PFE:

-54.82%

Current Drawdown

ISRG:

-2.13%

PFE:

-50.62%

Fundamentals

Market Cap

ISRG:

$191.94B

PFE:

$149.67B

EPS

ISRG:

$6.20

PFE:

$0.75

PE Ratio

ISRG:

86.92

PFE:

35.21

PEG Ratio

ISRG:

4.00

PFE:

0.20

Total Revenue (TTM)

ISRG:

$5.94B

PFE:

$45.86B

Gross Profit (TTM)

ISRG:

$3.99B

PFE:

$29.87B

EBITDA (TTM)

ISRG:

$1.95B

PFE:

$15.61B

Returns By Period

In the year-to-date period, ISRG achieves a 3.24% return, which is significantly higher than PFE's -0.45% return. Over the past 10 years, ISRG has outperformed PFE with an annualized return of 24.84%, while PFE has yielded a comparatively lower 2.35% annualized return.


ISRG

YTD

3.24%

1M

-0.13%

6M

23.03%

1Y

48.16%

5Y*

22.09%

10Y*

24.84%

PFE

YTD

-0.45%

1M

3.24%

6M

-7.80%

1Y

-2.35%

5Y*

-3.20%

10Y*

2.35%

*Annualized

Compare stocks, funds, or ETFs

Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.


Risk-Adjusted Performance

ISRG vs. PFE — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ISRG
The Risk-Adjusted Performance Rank of ISRG is 9595
Overall Rank
The Sharpe Ratio Rank of ISRG is 9494
Sharpe Ratio Rank
The Sortino Ratio Rank of ISRG is 9393
Sortino Ratio Rank
The Omega Ratio Rank of ISRG is 9191
Omega Ratio Rank
The Calmar Ratio Rank of ISRG is 9999
Calmar Ratio Rank
The Martin Ratio Rank of ISRG is 9797
Martin Ratio Rank

PFE
The Risk-Adjusted Performance Rank of PFE is 4242
Overall Rank
The Sharpe Ratio Rank of PFE is 4646
Sharpe Ratio Rank
The Sortino Ratio Rank of PFE is 3737
Sortino Ratio Rank
The Omega Ratio Rank of PFE is 3737
Omega Ratio Rank
The Calmar Ratio Rank of PFE is 4747
Calmar Ratio Rank
The Martin Ratio Rank of PFE is 4545
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

ISRG vs. PFE - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Intuitive Surgical, Inc. (ISRG) and Pfizer Inc. (PFE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


Sharpe ratio
The chart of Sharpe ratio for ISRG, currently valued at 1.97, compared to the broader market-2.000.002.001.97-0.06
The chart of Sortino ratio for ISRG, currently valued at 3.08, compared to the broader market-4.00-2.000.002.004.003.080.08
The chart of Omega ratio for ISRG, currently valued at 1.38, compared to the broader market0.501.001.502.001.381.01
The chart of Calmar ratio for ISRG, currently valued at 5.70, compared to the broader market0.002.004.006.005.70-0.02
The chart of Martin ratio for ISRG, currently valued at 17.95, compared to the broader market0.0010.0020.0017.95-0.15
ISRG
PFE

The current ISRG Sharpe Ratio is 1.97, which is higher than the PFE Sharpe Ratio of -0.06. The chart below compares the historical Sharpe Ratios of ISRG and PFE, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-1.000.001.002.003.004.00AugustSeptemberOctoberNovemberDecember2025
1.97
-0.06
ISRG
PFE

Dividends

ISRG vs. PFE - Dividend Comparison

ISRG has not paid dividends to shareholders, while PFE's dividend yield for the trailing twelve months is around 6.36%.


TTM20242023202220212020201920182017201620152014
ISRG
Intuitive Surgical, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
PFE
Pfizer Inc.
6.36%6.33%5.70%3.12%2.64%3.91%3.68%3.12%3.54%3.70%3.48%3.34%

Drawdowns

ISRG vs. PFE - Drawdown Comparison

The maximum ISRG drawdown since its inception was -82.25%, which is greater than PFE's maximum drawdown of -54.82%. Use the drawdown chart below to compare losses from any high point for ISRG and PFE. For additional features, visit the drawdowns tool.


-50.00%-40.00%-30.00%-20.00%-10.00%0.00%AugustSeptemberOctoberNovemberDecember2025
-2.13%
-50.62%
ISRG
PFE

Volatility

ISRG vs. PFE - Volatility Comparison

Intuitive Surgical, Inc. (ISRG) and Pfizer Inc. (PFE) have volatilities of 6.41% and 6.54%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.


4.00%6.00%8.00%10.00%12.00%AugustSeptemberOctoberNovemberDecember2025
6.41%
6.54%
ISRG
PFE

Financials

ISRG vs. PFE - Financials Comparison

This section allows you to compare key financial metrics between Intuitive Surgical, Inc. and Pfizer Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items
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Disclaimer

The information contained herein does not constitute investment advice and made available for educational purposes only. Prices and returns on equities are listed without consideration of fees, commissions, taxes, penalties, or interest payable due to purchasing, holding, or selling.

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