ISRG vs. MSFT
ISRG (Intuitive Surgical, Inc.) and MSFT (Microsoft Corporation) are both stocks. ISRG operates in Medical Instruments & Supplies (Healthcare), while MSFT operates in Software - Infrastructure (Technology). Over the past 10 years, ISRG returned 19.13%/yr vs 25.03%/yr for MSFT. At a 0.40 correlation, their price movements are largely independent.
Performance
ISRG vs. MSFT - Performance Comparison
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Returns By Period
In the year-to-date period, ISRG achieves a -28.09% return, which is significantly lower than MSFT's -11.24% return. Over the past 10 years, ISRG has underperformed MSFT with an annualized return of 19.13%, while MSFT has yielded a comparatively higher 25.03% annualized return.
ISRG
- 1D
- 1.24%
- 1M
- -9.96%
- YTD
- -28.09%
- 6M
- -28.51%
- 1Y
- -26.20%
- 3Y*
- 9.27%
- 5Y*
- 8.00%
- 10Y*
- 19.13%
MSFT
- 1D
- -3.17%
- 1M
- 3.54%
- YTD
- -11.24%
- 6M
- -10.15%
- 1Y
- -6.96%
- 3Y*
- 9.26%
- 5Y*
- 12.17%
- 10Y*
- 25.03%
ISRG vs. MSFT - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
ISRG Intuitive Surgical, Inc. | -28.09% | 8.51% | 54.72% | 27.14% | -26.15% | 31.76% | 38.39% | 23.43% | 31.23% | 72.64% |
MSFT Microsoft Corporation | -11.24% | 15.58% | 12.93% | 58.19% | -28.02% | 52.48% | 42.53% | 57.56% | 20.80% | 40.73% |
Correlation
The correlation between ISRG and MSFT is 0.23, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.23 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.43 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.54 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.57 |
Correlation (All Time) Calculated using the full available price history since Jun 19, 2000 | 0.40 |
The correlation between ISRG and MSFT shifts across timeframes, from 0.23 (1 year) to 0.57 (10 years), reflecting how their relationship changes across market environments.
Fundamentals
ISRG:
$146.54B
MSFT:
$3.18T
ISRG:
$8.24
MSFT:
$16.79
ISRG:
49.43
MSFT:
25.45
ISRG:
3.03
MSFT:
1.78
ISRG:
13.91
MSFT:
10.01
ISRG:
8.33
MSFT:
7.68
ISRG:
$10.58B
MSFT:
$318.27B
ISRG:
$7.02B
MSFT:
$217.41B
ISRG:
$3.76B
MSFT:
$200.96B
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Return for Risk
ISRG vs. MSFT — Risk / Return Rank
ISRG
MSFT
ISRG vs. MSFT - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Intuitive Surgical, Inc. (ISRG) and Microsoft Corporation (MSFT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| ISRG | MSFT | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.57 | ||
| Sortino ratioReturn per unit of downside risk | -1.02 | ||
| Omega ratioGain probability vs. loss probability | 0.86 | 0.97 | -0.11 |
| Calmar ratioReturn relative to maximum drawdown | -0.82 | -0.21 | -0.61 |
| Martin ratioReturn relative to average drawdown | -1.65 | -0.44 | -1.21 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| ISRG | MSFT | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | -0.85 | -0.28 | -0.57 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | 0.24 | 0.46 | -0.22 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.59 | 0.93 | -0.34 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.47 | 0.75 | -0.27 |
Drawdowns
ISRG vs. MSFT - Drawdown Comparison
The maximum ISRG drawdown since its inception was -82.26%, which is greater than MSFT's maximum drawdown of -69.38%. Use the drawdown chart below to compare losses from any high point for ISRG and MSFT.
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Drawdown Indicators
| ISRG | MSFT | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -82.26% | -69.38% | -12.88% |
Max Drawdown (1Y)Largest decline over 1 year | -32.14% | -33.91% | +1.77% |
Max Drawdown (3Y)Largest decline over 3 years | -34.10% | -33.91% | -0.19% |
Max Drawdown (5Y)Largest decline over 5 years | -49.90% | -37.15% | -12.75% |
Max Drawdown (10Y)Largest decline over 10 years | -49.90% | -37.15% | -12.75% |
Current DrawdownCurrent decline from peak | -33.28% | -20.67% | -12.61% |
Average DrawdownAverage peak-to-trough decline | -21.27% | -21.78% | +0.51% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 15.91% | 15.95% | -0.04% |
Volatility
ISRG vs. MSFT - Volatility Comparison
Intuitive Surgical, Inc. (ISRG) has a higher volatility of 11.07% compared to Microsoft Corporation (MSFT) at 9.95%. This indicates that ISRG's price experiences larger fluctuations and is considered to be riskier than MSFT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| ISRG | MSFT | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 11.07% | 9.95% | +1.12% |
Volatility (6M)Calculated over the trailing 6-month period | 20.23% | 22.34% | -2.11% |
Volatility (1Y)Calculated over the trailing 1-year period | 30.83% | 25.12% | +5.71% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 33.15% | 26.63% | +6.52% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 32.38% | 27.04% | +5.34% |
Dividends
ISRG vs. MSFT - Dividend Comparison
ISRG has not paid dividends to shareholders, while MSFT's dividend yield for the trailing twelve months is around 0.83%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
ISRG Intuitive Surgical, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
MSFT Microsoft Corporation | 0.83% | 0.70% | 0.73% | 0.74% | 1.06% | 0.68% | 0.94% | 1.20% | 1.69% | 1.86% | 2.37% | 2.33% |
Financials
ISRG vs. MSFT - Financials Comparison
This section allows you to compare key financial metrics between Intuitive Surgical, Inc. and Microsoft Corporation. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
ISRG vs. MSFT - Profitability Comparison
ISRG - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Intuitive Surgical, Inc. reported a gross profit of 1.83B and revenue of 2.77B. Therefore, the gross margin over that period was 66.1%.
MSFT - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Microsoft Corporation reported a gross profit of 56.06B and revenue of 82.89B. Therefore, the gross margin over that period was 67.6%.
ISRG - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Intuitive Surgical, Inc. reported an operating income of 855.30M and revenue of 2.77B, resulting in an operating margin of 30.9%.
MSFT - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Microsoft Corporation reported an operating income of 38.40B and revenue of 82.89B, resulting in an operating margin of 46.3%.
ISRG - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Intuitive Surgical, Inc. reported a net income of 821.50M and revenue of 2.77B, resulting in a net margin of 29.7%.
MSFT - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Microsoft Corporation reported a net income of 31.78B and revenue of 82.89B, resulting in a net margin of 38.3%.
Frequently Asked Questions
ISRG and MSFT have a correlation of 0.23, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
ISRG has higher volatility (11.07%) compared to MSFT (9.95%). In terms of maximum drawdown, ISRG dropped -82.26% vs MSFT's -69.38%.
MSFT currently has the higher Sharpe Ratio (-0.28 vs -0.85), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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